Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling by Chung, Jihyun

“…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …”
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The effect of clopidogrel and aspirin on the severity of traumatic brain injury in a rat model by Firas, Kobeissy

“…TBI increases UCHL-1 and GFAP, but decreases hexokinase expression compared to the non-injured controls. …”
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Optimal virtual network function placement in multi-cloud service function chaining architecture by Bhamare, Deval

“…Greedy approach has already been widely studied in the literature for the VM placement problem. Especially we compare our proposed heuristic with a greedy approach using first-fit decreasing (FFD) method. …”
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Estimation of Mechanical Properties of Copper Powder Filled Linear Low-Density Polyethylene Composites by Singh, S.

“…Conclusion: In line with the experimental data, we found that as we increased the volume fraction of the copper powder, the elongation and stress at break of the composites decreased, while the Young’s modulus increased.…”
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The mitochondria: A target of polyphenols in the treatment of diabetic cardiomyopathy by Bhagani, Humna

“…The most important intermediates by which polyphenols exert their protective effect include Bcl-2, UCP2, SIRT-1, AMPK and JNK1. Bcl-2 acts to attenuate apoptosis, UCP2 decreases oxidative stress, SIRT-1 increases mitochondrial biogenesis and decreases oxidative stress, AMPK increases autophagy, and JNK1 decreases apoptosis and increases autophagy. …”
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Does Securitisation Make Monetary Policy Less Effective? by Qanas, Jalal

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Impact of composition and salinity on swelling and gel strength of poly (acrylamide-co-acrylic acid) preformed particle gel by Ben Ali, Ahmed

“…The effects of various material compositions and reservoir environments on the ultimate strength and swelling kinetics of a commercial preformed particle gel (PPG) have been investigated. …”
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Factors associated with meeting current recommendation for physical activity in scottish adults with diabetes by Salman A.

“…Furthermore, meeting the recommended physical activity levels decreased with age (OR 0.96; 95% CI 0.95–0.97), having a longstanding illness (OR 0.56; 95% CI 0.34–0.93) and body mass index (OR 0.94; 95% CI 0.92–0.97), but increased with higher fruit and vegetable intake (OR 1.16; 95% CI 1.07–1.25) and mental wellbeing (OR 1.04; 95% CI 1.02–1.06). …”
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Mangifera indica L. kernel ethanol extract inhibits cell viability and proliferation with induction of cell cycle arrest and apoptosis in lung cancer cells by Alshwyeh, Hussah Abdullah

“…In this study, we investigated the effects of an ethanolic extract of Mangifera indica L. kernel on the viability and proliferation of human lung cancer cells. …”
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Edge-based compression and classification for smart healthcare systems: concept, implementation and evaluation by Awad Abdellatif A.

“…Our experimental results assess the performance of the proposed system in terms of data reduction, classification accuracy, battery lifetime, and transmission delay. We show the effectiveness of our system and its ability to outperform conventional remote monitoring systems that ignore data processing at the edge by: (i) achieving 98.3% classification accuracy for seizures detection, (ii) extending battery lifetime by 60%, and (iii) decreasing average transmission delay by 90%.…”
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Natural aging of shape stabilized phase change materials based on paraffin wax by Krupa, Igor

“…The addition of 15 wt% of EG to shape stabilized phase change materials (SSPCMs) containing 50 wt% of wax caused a decreasing in the leakage of wax by 50% over 210 days of natural aging. …”
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Effect of the length of silicon nano-dot/wire on band gap by Hassan, Walid M.I.

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EdgeHealth: An Energy-Efficient Edge-based Remote mHealth Monitoring System by Emam A.

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Towards Extended Bit Tracking for Scalable and Robust RFID Tag Identification Systems by Fahim A.

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Predicting academic success in health professions training and education: Insights from a data mining analysis by Bragazzi, Nicola Luigi

“…For the Academic Years 2008-2009 and 2009-2010 results of ad hoc psychological questionnaires investigating, among others, motivation and possible influences from the peer environment were also available. We found that attendance to the so called ‘tirocinio,’ an Italian word describing practical training activities and clinical placements, is the most important variable in terms of variance and that administrative social-demographic variables alone are sufficient to explain school success and achievement (AUC 0.99500 for 2007, AUC 0.98774 for 2008 and AUC 1.00000 for 2009). …”
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Investigating the utilization of healthcare services to manage respiratory tract infections (RTIs) among Qatari patients attended selected primary healthcare centers in Qatar by Islam, Nazmul

“…Highest number of patients with a comorbidity of Diabetes (12.85%), followed by Hypertension (10.54%). We have found no difference in the month-to-month rates of RTI-related GP visits (per 1000 total visits) over the study period (non-significant decreasing trend). …”
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A kernelized sparsity-based approach for best spectral bands selection for face recognition by Bouchech, H.J.

“…We formulate best spectral bands selection as a pursuit optimization problem wherein the vector of weights determining the importance of each visible spectral band is supposed to be sparse, and hence can be determined by minimizing its L1-norm. …”
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Consumption of some food groups is associated with the risk of cardiovascular disease among Jordanians by Tayyem, Reema

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Tandem osmotic engine based on hydrogel particles with antipolyelectrolyte and polyelectrolyte effect fuelled by both salinity gradient modes by Padmanabhan, Anjali Cheeramthodi

“…The swelling of hydrogel with a polyelectrolyte effect and shrinking of hydrogel particles possessing an antipoly-electrolyte effect in desalinated water, and subsequent shrinking of hydrogel with polyelectrolyte and swelling of hydrogel antipolyelectrolyte effect in saline water, generate power in both increasing and decreasing salinity modes. To investigate the energy recovery, we scrutinized osmotic engine assemblies by a setup arrangement of pistons with hydrogel particles, with polyelectrolyte and antipolyelectrolyte effects, in tandem. …”
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Thermally assisted efficient electrochemical lithium extraction from simulated seawater by Yanxi, Yu

“…Based on these understandings, we demonstrated that a thermally assisted electrochemical lithium extraction process could achieve rapid (36.8 mg g-1 day-1) and selective (51.79% purity) lithium extraction from simulated seawater with an ultrahigh Na+/Li+ molar ratio of 20,000. …”
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