Developmental and Neurobehavioral Toxicity of Hexaphenoxycyclotriphosphazene: Implications for Its Safety as a Flame-Retardant Alternative to Triphenyl Phosphate by Ruobing Bai (4860043)

“…Here, using zebrafish larvae with TPhP as a benchmark, we systematically evaluated the developmental and neurobehavioral toxicity of HPCTP at environmentally relevant concentrations (50–5000 ng/L) from 6 to 120 h postfertilization. …”

<i>In Vivo</i> Substrates of the Lens Molecular Chaperones αA-Crystallin and αB-Crystallin by Usha P. Andley (354477)

“…The amount of degraded glutamate dehydrogenase, α-enolase, and cytochrome c increased more than 50-fold in homozygous αA-R49C mutant lenses. In αB-R120G mouse lenses, our analyses identified decreased abundance of phosphoglycerate mutase, several β- and γ-crystallins, and degradation of αA- and αB-crystallin early in cataract development. …”

<i>CDKN3</i> mRNA as a Biomarker for Survival and Therapeutic Target in Cervical Cancer by Eira Valeria Barrón (796117)

“…<i>CDKN3</i> mRNA was on average 6.4-fold higher in tumors than in controls (p = 8 x 10⁻⁶, Mann-Whitney). A total of 68.2% of CC patients over expressing <i>CDKN3</i> gene (fold change ≥ 17) died within two years of diagnosis, independent of the clinical stage and HPV type (Hazard Ratio = 5.0, 95% CI: 2.5–10, p = 3.3 x 10⁻⁶, Cox proportional-hazards regression). …”

Image 1_Distinct brain and neurocognitive transformations after bariatric surgery: a pilot study.jpeg by Bhaswati Roy (2802559)

“…At six months, we observed reversal of brain alterations for most patients and a concomitant rebound of cognitive scores to patient’s baseline status.…”

Transmission of tuberculosis in rural Henan, China: a prospective population-based genomic spatial epidemiological study by Zhuo Quan (17658835)

“…The clustering risk decreased rapidly with increasing distances between patient residences, but 77.6% of clustered patient pairs lived ≥5.0 km apart. …”

Weak Compliance Undermines the Success of No-Take Zones in a Large Government-Controlled Marine Protected Area by Stuart J. Campbell (115219)

“…These declines in fish biomass were not driven by changes in habitat quality; coral cover increased in all zones, possibly as a result of a shift in fishing gears from those which can damage reefs (i.e., nets) to those which cause little direct damage (i.e., handlines and spears). …”

Sensitivity of various GFP insertion constructs (<i>columns A through J</i>) to protein misfolding. by Stéphanie Cabantous (92574)

“…<p>(A) Images of <i>E. coli</i> cells on plates expressing four test fusions proteins with decreasing folding robustness at 37°C. …”

Dynamic profiles of the prototypic integrated system under different conditions, and a comparison to the kinetic-based model. by Jong Min Lee (271984)

“…<p>The concentration of carbon and amount of biomass within the cellular system over a simulation time of 10 h is illustrated. The decreasing lines represent the concentration of carbon (as indicated by the left <i>y</i>-axis), which is being consumed, in the system. …”

Supplementary Information Files for 'The influence of climate change on the restoration trajectory of a nutrient-rich deep lake' by Alan D Radbourne (7534406)

“…This is of growing importance for many such lakes, given widespread climate-driven lengthening of stratification and a national trend of decreasing summer rainfall (decreasing seasonal flushing) but more intense summer storm events (resulting in short-term flushing events).…”

Proliposome tablets manufactured using a slurry-driven lipid-enriched powders: Development, characterization and stability evaluation by Khan I.

“…Moreover, the entrapment efficiency of BDP decreased from 57.43 � 9.12% to 17.93 � 5.37% following 18 months storage under HT conditions. …”
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Impact of clays on CO2 adsorption and enhanced gas recovery in sandstone reservoirs by Hamza A.

“…Clay-rich sandstone rocks, which have swellable clays such as illite, showed the highest CO2 uptake at a temperature of 50 °C and a pressure of 20 bars with total CO2 uptake of 4.6 and 2.6 mg/g for Kentucky and Scioto rocks, respectively. …”
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Ageing increases Arctic Aβ42 peptide accumulation and toxicity when transcript levels are equalised at different ages. by Iain Rogers (152860)

“…<p>UAS-Arctic Aβ42/+; elavGS/+ females were pulsed, for 1 week, either at 2 or 5 days old with 50 µM RU (RU 50 [2–9d] or [5–12d]) or 20 days old with 200 µM RU (RU 200 [20–27d]). …”

Data_Sheet_1_Sense of agency at a gaze-contingent display with jittery temporal delay.docx by Junhui Kim (18575083)

“…We manipulated the delay between eye movements and display updates using a truncated normal distribution (μ to μ + 2 σ) with μ ranging from 0 to 400 ms and σ fixed at 50 ms. …”

Dynamin inhibition by dynasore affects LTP, a type of synaptic plasticity due to sustained activity in hippocampus. by Mauro Fà (59065)

“…<p><b>A</b>, Dynasore (80 μM, 20 minute perfusion, open triangles) decreases LTP induced by theta-burst stimulation in CA₃–CA₁ synapses compared to vehicle-treated slices (black circles)(F_1,10 = 9.081, <i>p</i> = 0.013). …”

Table_1_Lactate Dehydrogenase as a Potential Therapeutic Drug Target to Control Babesia bigemina.docx by Lan He (219448)

“…Gossypol has a significant (P < 0.0001) inhibitory effect on the in vitro growth of B. bigemina, with IC₅₀ of 43.97 mM after 72 h of treatment. …”

Image_1_Lactate Dehydrogenase as a Potential Therapeutic Drug Target to Control Babesia bigemina.tif by Lan He (219448)

“…Gossypol has a significant (P < 0.0001) inhibitory effect on the in vitro growth of B. bigemina, with IC₅₀ of 43.97 mM after 72 h of treatment. …”

Data_Sheet_1_The APSES Gene MrStuA Regulates Sporulation in Metarhizium robertsii.DOC by Wenjing Yang (466552)

“…We also show that the median lethal time (LT₅₀) of the mutant increased by 19%. This increase corresponded with a slower growth rate and an earlier conidia germination time compared to that of the wild strain. …”

A Retrospective Survey of Research Design and Statistical Analyses in Selected Chinese Medical Journals in 1998 and 2008 by Zhichao Jin (248636)

“…The overall error/defect proportion of study design also decreased ( = 21.22, p<0.001), 50.9% (680/1,335) compared to 42.40% (669/1,578). …”

Measuring the Effectiveness of Conservation: A Novel Framework to Quantify the Benefits of Sage-Grouse Conservation Policy and Easements in Wyoming by Holly E. Copeland (369907)

Safety assessment of a novel C-type natriuretic peptide derivative and the mechanism of bone- and cartilage-specific toxicity by Takafumi Yotsumoto (4994390)

“…A decrease in the bone mineral density (BMD) of the femur also was associated with the appearance of bone toxicity. …”