Effect of myricetin on <i>P</i>. <i>gingivalis</i>-induced NF-κB activation using the U937-3xκB-LUC cell line model. by Daniel Grenier (522918)

Data Sheet 1_Association between dietary vitamin K intake and lipid metabolism among populations with cardiovascular disease.docx by Tao Liu (10785)

“…The total daily intake of dietary vitamin K was found to be negatively correlated with TG (β: −15.57, 95% CI: −27.806, −3.333) and TC (β: −6.564, 95% CI: −12.252, −0.877). For each 1 ug increase in the total daily intake of dietary vitamin K, the LDL-C would decrease by 0.510 mg/dl (95% CI: −0.940, −0.078) when the total daily intake of dietary vitamin K was less than 23.7 ug. …”

Thirty-year Trends in Complications in U.S. Adults With Newly Diagnosed Type 2 Diabetes by Michael Fang (9708234)

“…</p> <p><b>Results: </b>From 1988-1994 to 2011-2018, there was a significant decrease in the prevalence of albuminuria (38.9 to 18.7%, p-for-trend<0.001), but no change in the prevalence of reduced eGFR (7.5 to 9.9%, p-for-trend=0.30), retinopathy (1988-1994 to 1999-2008 only; 13.2 to 12.1%, p-for-trend=0.86), or self-reported cardiovascular disease (19.0 to 16.5%, p-for-trend=0.64). …”

Supplementary Material for: Role of melatonin in intestinal mucosal injury induced by chronic restraint stress in mice by figshare admin karger (2628495)

“…Results: Mice subjected to restraint stress presented elevated CORT and NE levels of 141.41% and 151.24%, respectively, and a decreased plasma MT content of 37.12%. Consistent with the decrease in MT levels, we observed a reduction in antioxidant ability and autophagic proteins and increased apoptotic protein levels in the gut, resulting in injury to the intestinal mucosa, which manifested as reductions in the villus height and the V/C ratio; the number of goblets; the number of mast and PCNA-positive cells; and the expression of tight junction proteins (ZO-1, occludin and claudin-1). …”

Additional sleep does not restore attention in <i>upd2</i> knockdown flies. by Deniz Ertekin (9199661)

“…<p>(A) Total sleep duration in THIP-fed flies (0.1 mg/mL) was increased (compared with the same genotypes in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3000548#pbio.3000548.g002" target="_blank">Fig 2</a>). …”

Serum levels of cholesterol and triglycerides in ISR2 mice. by Ke Ma (260231)

“…The data are expressed as mg/dl and represent the Mean ± SE from 4 animals per group. * P<0.05 as compared to WT. …”

Conversion of ammonium to nitrate and abundance of ammonium-oxidizing-microorganism in Tropical soils with nitrification inhibitor by Gabriel Barth (4698967)

“…During 90 days of incubation, the effectiveness of DCD in reducing NO3–-N production was 1.8, 86.4, and 145.6 mg kg–1, while the effectiveness of DCD in reducing AOM abundance was 1.2, 3.0 and 2.3 × 10–3 g soil–1 for sandy, loamy, and clayey soils, respectively. …”

Determination of optimal allopregnanolone treatment regimen. by Shuhua Chen (11649)

“…Brain sections from 3xTgAD mice treated with APα (10 mg/kg) or vehicle were stained. Aβ immunoreactivity was detected with 6E10 antibody (green) and nuclei counter-stained with DAPI (blue). …”

New insights into the limited thermotolerance of anhydrobiotic tardigrades by Ricardo Cardoso Neves (9301134)

“…Here, we investigate the effect of 1 week of high temperature exposures on desiccated tardigrades with the aim of elucidating whether exposure-times longer than 24 hours decrease survival even further. From our analyses we estimate a significant decrease in the 50% mortality temperature from 63ºC to 56ºC for <i>Ramazzottius varieornatus</i> exposed to high temperatures in the desiccated tun state for 24 hours and 1 week, respectively. …”

Nanobody treatment leads to changes in norovirus capsid morphology. by Anna D. Koromyslova (1816249)

“…Nano-26, Nano-85, and citrate caused a significant decrease in genome copy levels compared to Nano-14. …”

FigShare Figure 4. Targetable sites to introduce pathogenic variants with prime editors. by John Morris (8904362)

“…<b>(a)</b> Total number of ClinVar pathogenic variants, broken down by mutation type (transition, transversion, insertion or deletion) and the decrease in the percentage that can be introduced with prime editing under different conditions. …”

Sec24D regulates intracellular Proinsulin abundance. by Jeffrey Viviano (8871581)

“…(B) Densitometric quantification of the relative abundance of Sec24D in transiently transfected Min-6 cells indicate a decrease in Sec24D levels of ~50% when transfected with Sec24D-targeted siRNA vs. controls (n = 5, p = 0.0117). …”

Examination of human interference and abundance upon plants and animals species richness by Geethanjanen Raveendhran (3113937)

“…<p><b>Meta Data:</b></p> <p>1) Abundance Native Plants: This is a discrete variable. A 50 m transect was placed along the length of the pond area and the impermeable surface. …”

Characteristics induced by 2 weeks exposure of SRA01/04 cells to low-doses of H₂O₂. by Zi-Feng Zhang (341807)

“…<p>A. Shows that cell viability (Left) of SRA01/04 cells decreases with increasing concentrations of H₂O₂ as measured by the MTT assay (Mean± SD; n = 5.). …”

Data_Sheet_1_Low-Cost Microwave-Assisted Partial Pseudomorphic Transformation of Biogenic Silica.docx by Denise Schneider (6983711)

“…The target values were a specific surface area of ~500 m² g⁻¹ and a mesopore volume of ~0.40–0.50 cm³ g⁻¹ as these values are industrially relevant and are reached by potential concurring products such as precipitated silica, silica gel, and fumed silica. …”

Gene expression evaluation of antioxidant enzymes in patients with hepatocellular carcinoma: RT-qPCR and bioinformatic analyses by Andressa de Freitas Alves (12820376)

“…GPX4 expression was significantly increased (p=0.02), while SOD2 expression was significantly decreased (p=0.04) in experimental data. In TCGA samples, alpha-fetoprotein levels (mg/dL) were negatively correlated with the expression of SEP15 (p<0.001), SELENOP (p<0.001), SOD1 (p<0.001), SOD2 (p<0.001), CAT (p<0.001), and NFE2L2 (p=0.004). …”

Factors associated to the frailty phenotype components among hospitalized elderly patients by Lorraine Cristina Silva (6485201)

“…The following associated factors were identified: self-report of exhaustion and/or fatigue [depression indicative (OR: 3.12; CI: 1.69-5.75)]; decreased muscle strength [advanced age (OR:2.20; CI: 1.40-3.47); absence of partner (OR: 1.86, CI: 1.023.39); inability to perform basic (OR: 2.38; CI: 1.27-4.44) and instrumental (OR: 2.53; CI: 1.29-4.97) activities of the daily living]; slow gait speed [women (OR:2.13; CI:1.16-3.92), advanced age (OR:2.90; CI:1.82-4.61), inability to perform instrumental activities of the daily living (OR:2.08; CI:1.14-3.77); and low level of physical activity [advanced age (OR: 1.57; CI: 1.01-2.44)]. …”

Data_Sheet_1_Human milk nutritional composition across lactational stages in Central Africa.docx by Violeta Moya-Alvarez (347148)

“…The median levels of total amino acids in HM dropped from 12.8 mg/ml at week 1 to 7.4 mg/ml at week 25. In contrast, specific free amino acids increased between months 1 and 3 of lactation, e.g., free glutamic acid, glutamine, aspartic acid, and serine. …”

(a) Western blotting showed levels of STAT-1 in brain tissue of rats by Fei Cai (43088)

Supplementary file 1_Improvement of the photorefractive response in bismuth and magnesium co-doped lithium niobate crystals via oxygen-vacancy modulation through controlled redox a... by Shuolin Wang (16339020)