Assessing the disparity: comparative toxicity of Copper in zebrafish larvae exposes alarming consequences of permissible concentrations in Brazil by Maria Vitória Takemura Mariano (17613858)

“…<p>Copper (Cu) is a naturally occurring metal with essential micronutrient properties. …”

Data Sheet 1_RvD2 mitigates TNFɑ-Induced mitochondrial reactive oxygen species through NRF2 signaling in placental trophoblasts.pdf by Taija Hahka (20983223)

“…In contrast, TNFα alone decreases nuclear NRF2 levels, increases mitochondrial ROS and oxygen consumption rates, and impairs migration. …”

Table_1_High-Throughput Analysis of Water-Soluble Forms of Choline and Related Metabolites in Human Milk by UPLC-MS/MS and Its Application.DOCX by Daniela Hampel (683851)

“…Milk from Brazilian women (2–8, 28–50, and 88–119 days postpartum, n_total = 53) revealed increasing concentration throughout lactation for glycerophosphocholine, DMG, and methionine, while carnitine decreased. …”

Presentation_1_Environmental Concentrations of Sulfonamides Can Alter Bacterial Structure and Induce Diatom Deformities in Freshwater Biofilm Communities.pdf by Laura Kergoat (10761429)

“…The increase of both diatom growth rate and mortality suggests a high renewal of diatoms under sulfonamide exposure. …”

Supplementary file 1_Comparative analysis of accuracy and completeness in standardized database generation for complex multilingual lung cancer pathological reports: large language... by Hao Hang (7037264)

“…In English reports, it matched mainstream AI in lesion analysis (p > 0.05) but excelled in lymph node/pathology metrics (p < 0.05). Task load scores decreased by 38.3% post-implementation (413.90 ± 78.09 vs. 255.30 ± 65.50, t = 26.481, p < 0.001).…”

Subsoiling practices change root distribution and increase post-anthesis dry matter accumulation and yield in summer maize by Xuefang Sun (758578)

“…Density of root dry weight at 10–50 cm depth with SS increased by 40.68%, 32.17%, and 20.14% at low, medium, and high planting densities compared to CK, respectively, while the root bleeding sap amount increased by 17.41%, 15.82%, and 20.91%. …”

Mode of action of the antimicrobial peptide Mel4 is independent of <i>Staphylococcus aureus</i> cell membrane permeability by Muhammad Yasir (3555896)

“…<div><p>Mel4 is a novel cationic peptide with potent activity against Gram-positive bacteria. …”

EZH2 Is Associated with Malignant Behavior in Pancreatic IPMN via p27^Kip1 Downregulation by Hideyuki Kuroki (607412)

“…</p><p>Methods</p><p>Fifty-four surgically resected pancreatic IPMN specimens, including a total of 181 lesions (normal duct in 48, adenoma in 50, borderline atypia in 53, carcinoma in situ (CIS) in 19, and invasive carcinoma in 11) were analyzed by immunohistochemical staining (EZH2, Ki-67, p27^Kip1). …”

Table_1_Granulocyte Colony-Stimulating Factor Accelerates the Recovery of Hepatitis B Virus-Related Acute-on-Chronic Liver Failure by Promoting M2-Like Transition of Monocytes.docx by Jingjing Tong (2572018)

“…In the G-CSF-treated group, the monocyte counts on days 0 and 7 were independently associated with an evaluated mortality risk in the fully adjusted model (Model 3) [at day 0: hazard ratio (HR) 95% confidence interval (CI): 15.48 (3.60, 66.66), P = 0.0002; at day 7: HR (95% CI): 1.10 (0.50, 2.43), P=0.8080]. Further analysis showed that after treatment with G-CSF in HBV-ACLF patients, the expression of M1-like markers (HLA-DR and CD86) in monocytes decreased (HLA-DR: P = 0.0148; CD86: P = 0.0764). …”

Data_Sheet_1_Food Web Functions and Interactions During Spring and Summer in the Arctic Water Inflow Region: Investigated Through Inverse Modeling.docx by Kalle Olli (288500)

“…The model was based on three intensively sampled stations during both periods, corresponding to early, peak, and decline phases of a Phaeocystis and diatom dominated bloom (May), and flagellates dominated post bloom stages (August). …”

Table_1_Insights into melatonin-induced photosynthetic electron transport under low-temperature stress in cucumber.xlsx by Pei Wu (327833)

“…The results indicated that moderate concentrations of MT had a positive effect on the growth of low temperature-stressed cucumber seedlings. …”

Table_2_Macrophage polarization regulates intervertebral disc degeneration by modulating cell proliferation, inflammation mediator secretion, and extracellular matrix metabolism.do... by Xiao-Chuan Li (3753502)

“…M1CM injection decreased ECM anabolic and increased ECM catabolic, as well as the upregulation of inflammation-related genes after 8 weeks treatment, while M2CM slowed down these trends. …”

Table_3_Dynamic increase in myoglobin level is associated with poor prognosis in critically ill patients: a retrospective cohort study.docx by Yishan Liu (10808097)

“…However, the relationship between its dynamic changes and prognosis remains unclear.</p>Methods<p>We retrospectively enrolled 11,218 critically ill patients from a general and surgical intensive care unit (ICU) of a tertiary hospital between June 2016 and May 2020. …”

Table_1_Factors associated with COVID-19 vaccine confidence among primary care providers in Kazakhstan, March–April 2021.docx by Dilyara Nabirova (14241346)

“…</p>Methods<p>From March to April 2021, we conducted a cross-sectional study among the healthcare providers responsible for vaccination in 54 primary care facilities in three cities in Kazakhstan. …”

Stability of Circulating Blood-Based MicroRNAs – Pre-Analytic Methodological Considerations by Charlotte Glinge (3639325)

“…</p><p>Methods</p><p>Blood samples were collected from 12 healthy donors into different collection tubes containing anticoagulants, including EDTA, citrate and lithium-heparin, as well as into serum collection tubes. …”

DataSheet_1_Integrated analysis of immune parameters, miRNA-mRNA interaction, and immune genes expression in the liver of rainbow trout following infectious hematopoietic necrosis... by Shenji Wu (12553825)

“…Currently, little is known about the immune defense mechanisms of rainbow trout against IHNV. In this study, we detected the changes of immune parameters over different post-infection periods (6-, 12-, 24-, 48-, 72-, 96-, 120-, and 144 hours post-infection (hpi)), mRNA and miRNA expression profiles under 48 hpi (T48L) compared to control (C48L), and key immune-related genes expression patterns in rainbow trout liver following IHNV challenge through biochemical methods, RNA-seq, and qRT-PCR, and the function of miR-330-y was verified by overexpression and silencing in vitro and in vivo. …”

Datasheet1_Low total cholesterol predicts early death in children with hemophagocytic lymphohistiocytosis.zip by Li Xiao (307908)

“…</p>Conclusion<p>Severe derangement of lipoproteins is common in children with HLH, and decreased TC is an independent risk factor for early death. …”

Image_14_Organelle Crosstalk Regulators Are Regulated in Diseases, Tumors, and Regulatory T Cells: Novel Classification of Organelle Crosstalk Regulators.tif by Ming Liu (105953)

“…<p>To examine whether the expressions of 260 organelle crosstalk regulators (OCRGs) in 16 functional groups are modulated in 23 diseases and 28 tumors, we performed extensive -omics data mining analyses and made a set of significant findings: (1) the ratios of upregulated vs. downregulated OCRGs are 1:2.8 in acute inflammations, 1:1 in metabolic diseases, 1:1.2 in autoimmune diseases, and 1:3.8 in organ failures; (2) sepsis and trauma-upregulated OCRG groups such as vesicle, mitochondrial (MT) fission, and mitophagy but not others, are termed as the cell crisis-handling OCRGs. …”

Image_2_Factors associated with COVID-19 vaccine confidence among primary care providers in Kazakhstan, March–April 2021.pdf by Dilyara Nabirova (14241346)

“…</p>Methods<p>From March to April 2021, we conducted a cross-sectional study among the healthcare providers responsible for vaccination in 54 primary care facilities in three cities in Kazakhstan. …”

Image_3_The hidden crisis: double burden of malnutrition among refugee children in South Asia – a systematic review and meta-analysis from observational studies.JPEG by Pooja Panchal (20696588)

“…The prevalence of stunting ranged from 3.9–75.4% in the included studies [pooled prevalence: 31.8% (95% CI: 18.6–46.6%)]; wasting between 0.3–24.3% [pooled prevalence:10.1% (95% CI: 4.6–17.3)]; underweight between 4.4–65% [pooled prevalence: 19.1% (95% CI: 10.8–29.2%)]; and overweight between 3 and 24% [pooled prevalence: 6.5% (95% CI: 2.6–12.1%)]. Time trend analysis of the prevalence of malnutrition showed a decreasing trend in underweight, an increasing trend for stunting and wasting, and overweight including a rising prevalence of dual burden of under-and overnutrition.…”