Chordoma preclinical models are insensitive to BAF complex inhibitor FHD-286, alone or in combination with gemcitabine by Chordoma Foundation (4391989)

“…A panel of 4 chordoma cell lines were seeded in a white-walled 96-well plate so that at the start of treatment, 36 hours after plating, the confluence was 15%. …”

DataSheet1_Cold water immersion of the hand and forearm during half-time improves intermittent exercise performance in the heat.PDF by Manami Iwahashi (16076549)

“…Moreover, there was a significant decrease in the rectal (0.54 ± 0.17°C, p < 0.001) and mean skin (1.86 ± 0.34°C, p < 0.05) temperatures of the COOL condition during HT. …”

Flight Scheduling in the Airspace by Msakni, Mohamed Kais

“…The mathematical model has been solved using CPLEX 12.6 and the scatter search has been coded using C language under Microsoft Visual Studio v12 environment. …”
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Effects of PP on the proliferation of liver cancer cell lines. by Wenwen Xu (175846)

“…</b> The colony-formation assay demonstrated a dose-dependent decrease in liver cancer cell proliferation (Huh7, Hep3B, HepG2 and SMMC-7721) when exposure to PP. …”

Acute TTBK1 inhibition reduces tau phosphorylation at disease relevant sites <i>in vivo</i>. by Gregory M. Dillon (8681430)

“…(A) At the highest dose tested (75mg/kg), there was a significant decrease in tau phosphorylation at several sites when quantified by immunoblotting (S422, AT180, S396, and AT8). …”

TBr inhibited cell proliferation in leukemia cell lines. by Anup S. Pathania (657368)

“…<p>(A–B) Cell proliferation assay. Cells were treated with 1, 10, 30, 50 and 100 µM concentrations of TBr for 24 and 48 h. …”

Climatic factors driving vegetation declines in the 2005 and 2010 Amazon droughts by Wenqian Zhao (3937202)

“…The results showed that (i) in the Amazon vegetation greenness responded to precipitation, radiation and temperature, with apparent time lags for most averaging interval periods associated with vegetation index responses of 0–4, 0–9 and 0–6 months, respectively; (ii) on average, the three climatic factors without time lags explained 27.28±21.73% (mean±1 SD) of vegetation index variation in the Amazon basin, and this value increased by 12.22% and reached 39.50±27.85% when time lags were considered; (iii) vegetation greenness in this region in non-drought years was primarily affected by precipitation and shortwave radiation, and these two factors altogether accounted for 93.47% of the total explanation; and (iv) in the common epicenter of the two droughts, pixels with a significant variation in precipitation, radiation and temperature accounted for 36.68%, 40.07% and 10.40%, respectively, of all pixels showing a significant decrease in vegetation index in 2005, and 15.69%, 2.01% and 45.25% in 2010, respectively. …”

Delineating and identifying long-term changes in the whooping crane (<i>Grus americana</i>) migration corridor by Aaron T. Pearse (4856935)

“…This shift occurred from northern Oklahoma to central Saskatchewan at an average rate of 1.2 km/year (0.3–2.8 km/year). Associated with this directional shift was a decrease in distance of locations from the median in the same region averaging -0.7 km/year (-0.3–-1.3 km/year), suggesting a modest narrowing of the migration corridor. …”

Tannic acid blocks an early step of HCV entry. by Shuanghu Liu (307907)

“…Huh7.5 cells were inoculated with HCV JFH1-AM120-Rluc at a MOI of 10 for one hour at 4°C in presence of 50 μM of tannic acid, 500 μg/ml of heparin or no inhibitor as a control. …”

DataSheet_1_Improving in-season wheat yield prediction using remote sensing and additional agronomic traits as predictors.docx by Adrian Gracia-Romero (11046789)

“…This was particularly evident when NDVI saturates (with yields above 8 t ha^-1) with models including NDVI and days to heading providing a 50% increase in the prediction accuracy and a 10% decrease in the root mean square error. …”

Absence of beta-actin during primitive erythropoiesis correlates with reduced Gata2 expression levels in the yolk sac. by Davina Tondeleir (426905)

“…At E10.25, we could demonstrate a 50% increase of Vegf mRNA expression. Error bars represent mean ±SEM; *P<.05. …”

Mechanism of <i>S.</i> Typhimurium-induced intestinal damage during colitis. by Parag Kundu (232448)

Removal of Sialic Acids from Human Sebocytes by Sialidase Increases Their Susceptibility to <i>P. acnes.</i> by Teruaki Nakatsuji (39298)

Antioxidant glutathione and NAC restore the reduced ΔΨ_m in <i>DJ-1</i>−/− MEFs. by Emilie Giaime (316501)

“…<p>(<b>A, B</b>) Confocal microscopic analysis. (<b>A</b>) Representative confocal live cell images of <i>DJ-1</i>−/− and +/+ MEFs stained with TMRM (50 nM, red) and Mitotracker Green (200 nM) after incubation with or without glutathione (Glu, 10 mM, 24 hr) or NAC (20 mM, 24 hr). …”

Visual processing of symbology in head-fixed large Field-of-View displays by Frank L. Kooi (6645322)

“…<br> <i>Methods</i>. We measured the ability of 12 subjects to quickly determine the orientation (Т vs Ʇ) of a target T surrounded by 4 randomly oriented (up, down, left, right) flanker T’s as a function of 1) target-flanker spacing or ‘crowding’ (small /medium/large), 2) flanker polarity, and 3) eccentricity (15/30/45 deg). …”

Table_2_The Role of the Vascular Endothelial Growth Factor (VEGF) Signaling in Biomineralization of the Oyster Crassostrea gigas.DOCX by Anna V. Ivanina (5688974)

“…The involvement of VEGF and VEGFR in biomineralization was demonstrated in sea urchin larvae but its role in the biomineralization of other invertebrate groups such as mollusks is not known. We assessed the potential role of VEGF signaling on biomineralization of a model marine bivalve, the Pacific oyster Crassostrea gigas, by analyzing the effects of a VEGFR inhibitor (50 nM axitinib) on shell growth, shell hardness, and expression profiles of biomineralization-related genes. …”

Table_1_The Role of the Vascular Endothelial Growth Factor (VEGF) Signaling in Biomineralization of the Oyster Crassostrea gigas.DOCX by Anna V. Ivanina (5688974)

“…The involvement of VEGF and VEGFR in biomineralization was demonstrated in sea urchin larvae but its role in the biomineralization of other invertebrate groups such as mollusks is not known. We assessed the potential role of VEGF signaling on biomineralization of a model marine bivalve, the Pacific oyster Crassostrea gigas, by analyzing the effects of a VEGFR inhibitor (50 nM axitinib) on shell growth, shell hardness, and expression profiles of biomineralization-related genes. …”

Visual processing of symbology in head-fixed large Field-of-View displays by Frank L. Kooi (6645322)

“…<br> <i>Methods</i>. We measured the ability of 12 subjects to quickly determine the orientation (Т vs Ʇ) of a target T surrounded by 4 randomly oriented (up, down, left, right) flanker T’s as a function of 1) target-flanker spacing or ‘crowding’ (small /medium/large), 2) flanker polarity, and 3) eccentricity (15/30/45 deg). …”

Data_Sheet_1_The Role of the Vascular Endothelial Growth Factor (VEGF) Signaling in Biomineralization of the Oyster Crassostrea gigas.PDF by Anna V. Ivanina (5688974)

“…The involvement of VEGF and VEGFR in biomineralization was demonstrated in sea urchin larvae but its role in the biomineralization of other invertebrate groups such as mollusks is not known. We assessed the potential role of VEGF signaling on biomineralization of a model marine bivalve, the Pacific oyster Crassostrea gigas, by analyzing the effects of a VEGFR inhibitor (50 nM axitinib) on shell growth, shell hardness, and expression profiles of biomineralization-related genes. …”

Table_1_Longitudinal Gut Bacterial Colonization and Its Influencing Factors of Low Birth Weight Infants During the First 3 Months of Life.DOCX by Cheng Chi (655368)

“…Alpha-diversity of both groups displayed a decreasing trend followed by slight variations. …”