CBE and isofagomine effectively inhibit purified GBA1 at 1 mM and 1 μM, respectively. by Zdenek Berger (440685)

“…The graph shows a summary of three independent experiments. E) Addition of sodium taurocholate (NaTc) increases activity of GBA1 ~ 5-fold but decreases activity of GBA3 by ~ 50%. …”

Macrophage-tropic HIV-1 isolates, which are known to bind human CD4 more tightly, are promiscuous in their use of primate CD4 receptors. by Cody J. Warren (563898)

“…Error bars are not plotted in instances in which the size of the error bar is less than the symbol size. IC₅₀ values from the soluble CD4 neutralization assays are shown within each panel, for which the mean and SD values reflect the variation of the IC₅₀ calculations from two independent experiments. …”

Mechano–polarity feedback induces spontaneous and robust cell shape change and tissue deformation. by Fu-Lai Wen (11798016)

“…<p>(A) The deviation of apical domain (<i>ℓ</i>_domain) from its homeostatic size () following a decrease (<i>P</i>_<i>total</i> = 0.9) of total concentration of <i>P</i> plotted as a function of time (top) with the corresponding time evolution of <i>ψ</i> and <i>L</i> normalized by their initial values (bottom). …”

Nanoclay compatibilization of phase separated polysulfone/polyimide films for oxygen barrier by Ammar, Ali

“…Thermal decomposition (TGA) measurements of PSF/PI films showed a decrease in thermal stability upon adding C30B due to its surfactant modification, while film mechanical tensile modulus properties improved slightly by adding low concentration of C30B (~ 1 mass%), but higher nanoclay loading decreased tensile strength and elongation at break. …”
Get full text
Get full text

Artery Wall Assessment Helps Predict Kidney Transplant Outcome by Domingo Hernández (4919257)

“…This could lead to a higher post-transplant mortality. Pre-transplant c IMT, post-transplant diabetes and triglycerides at 1-year post-transplantation may condition a high c-IMT measurement post-transplantation, which may decrease patient survival.…”

Effect of AAS27 and AAS41 cocktail on expression of pro-inflammatory and anti-inflammatory cytokines by MΦ that were first activated with LPS or cocktail of r<i>Aam</i>IGFBP-rP1, r... by Mariam Bakshi (7962230)

Modulation of HTT levels, as evidenced by MAB2174 and EM48 immunoreactivity in the striatum of zQ175 heterozygous mice by AAV2 viruses expressing HTT-targeting shRNAs. by Nikisha Carty (395638)

Factors affecting fluoroscopy time during percutaneous nephrolithotomy: Impact of stone volume distribution in renal collecting system by Sait Özbir (8184177)

Image_6_Alcohol Impairs Immunometabolism and Promotes Naïve T Cell Differentiation to Pro-Inflammatory Th1 CD4+ T Cells.tif by Patrick M. McTernan (341264)

“…These results suggest that ethanol impairs CD4⁺ T cell immunometabolism and disrupts mitochondrial repair processes as it promotes CD4⁺ T cell differentiation to a pro-inflammatory phenotype.</p>…”

Image_4_Alcohol Impairs Immunometabolism and Promotes Naïve T Cell Differentiation to Pro-Inflammatory Th1 CD4+ T Cells.tif by Patrick M. McTernan (341264)

“…These results suggest that ethanol impairs CD4⁺ T cell immunometabolism and disrupts mitochondrial repair processes as it promotes CD4⁺ T cell differentiation to a pro-inflammatory phenotype.</p>…”

Image_2_Alcohol Impairs Immunometabolism and Promotes Naïve T Cell Differentiation to Pro-Inflammatory Th1 CD4+ T Cells.tif by Patrick M. McTernan (341264)

“…These results suggest that ethanol impairs CD4⁺ T cell immunometabolism and disrupts mitochondrial repair processes as it promotes CD4⁺ T cell differentiation to a pro-inflammatory phenotype.</p>…”

Image_5_Alcohol Impairs Immunometabolism and Promotes Naïve T Cell Differentiation to Pro-Inflammatory Th1 CD4+ T Cells.tif by Patrick M. McTernan (341264)

“…These results suggest that ethanol impairs CD4⁺ T cell immunometabolism and disrupts mitochondrial repair processes as it promotes CD4⁺ T cell differentiation to a pro-inflammatory phenotype.</p>…”

Image_3_Alcohol Impairs Immunometabolism and Promotes Naïve T Cell Differentiation to Pro-Inflammatory Th1 CD4+ T Cells.tif by Patrick M. McTernan (341264)

“…These results suggest that ethanol impairs CD4⁺ T cell immunometabolism and disrupts mitochondrial repair processes as it promotes CD4⁺ T cell differentiation to a pro-inflammatory phenotype.</p>…”

Image_1_Alcohol Impairs Immunometabolism and Promotes Naïve T Cell Differentiation to Pro-Inflammatory Th1 CD4+ T Cells.tif by Patrick M. McTernan (341264)

“…These results suggest that ethanol impairs CD4⁺ T cell immunometabolism and disrupts mitochondrial repair processes as it promotes CD4⁺ T cell differentiation to a pro-inflammatory phenotype.</p>…”

Determination of mitochondrial temperature in intact human cells. by Dominique Chrétien (217681)

“…Note that the initial value is given systematically as 50%, as set automatically by the spectrofluorometer (under these conditions; photo multiplier tension about 500 mV), allowing either increases or decreases to be recorded. …”

Establishment of Replicating Mycobacterium tuberculosis in an Aerosol Mouse Model of Infection: Active vs. Chronic Infection by Larry Bowen (5750969)

“…Results post termination of treatment (Day 60) with INH demonstrated a moderate decrease in bacterial load once the infection was considered chronic around Day 20.…”

Effect of CA-Inhibitors on sperm beat frequency and CA-activity. by Petra M. Wandernoth (149629)

“…The addition of varying EZA concentrations results in a decrease of enzymatic activity of between 35.0% (4.53±0.87 U/ml) for 50 nM EZA and 62.12% (2.72±0.12 U/ml) for 5 µM EZA (<i>n</i> = 6). …”

Data_Sheet_1_Long-Term Prognosis of Cognitive Function in Patients With Idiopathic Normal Pressure Hydrocephalus After Shunt Surgery.xlsx by Akihiro Kambara (10006775)

“…The patients were classified in to the cognitive decline group [11 (23%) patients; a decrease in the MMSE score by ≥ 2 points 2 years after surgery] and the maintenance/improvement group [37 (77%) patients]. …”

Characterizing suboptimal child passenger safety practices in crashes with fatalities: Child, driver, vehicle, neighborhood, and policy factors by Arthi S. Kozhumam (14176683)

“…There was a decrease in suboptimal child passenger safety practices with increasing vehicle model year, COI level, fines, and law scores. …”

Data_Sheet_2_The burden of epilepsy in the People’s Republic of China from 1990 to 2019: epidemiological trends and comparison with the global burden of epilepsy.PDF by Yun Shu (2016445)

“…Background<p>Epilepsy is associated with a significant global burden of disease, affecting over 50 million people worldwide. …”