Pentoxifylline, dexamethasone and azithromycin demonstrate distinct age-dependent and synergistic inhibition of TLR- and inflammasome-mediated cytokine production in human newborn... by Esther M. Speer (5158913)

“…<div><p>Introduction</p><p>Neonatal inflammation, mediated in part through Toll-like receptor (TLR) and inflammasome signaling, contributes to adverse outcomes including organ injury. Pentoxifylline (PTX), a phosphodiesterase inhibitor which potently suppresses cytokine production in newborn cord blood, is a candidate neonatal anti-inflammatory agent. …”

Data_Sheet_1_Effect of breathing intervention in patients with COVID and healthcare workers.docx by Manjari Rain (10169170)

“…D-dimer was the primary outcome, which remained below 0.50 μg/ml (a cutoff value to define severity) in the COVID-positive yoga group (CYG) and decreased in the COVID-recovered yoga group (RYG) and the HCW yoga group (HYG) after intervention. …”

Data Sheet 1_The green tea component (−)-epigallocatechin-3-gallate protects against cytokine-induced epithelial barrier damage in intestinal epithelial cells.pdf by Rita Rosenthal (285303)

“…Among other beneficial effects, EGCG was shown to be protective in inflammatory bowel disease (IBD), a condition associated with barrier dysfunction. …”

Image 3_The green tea component (−)-epigallocatechin-3-gallate protects against cytokine-induced epithelial barrier damage in intestinal epithelial cells.tif by Rita Rosenthal (285303)

“…Among other beneficial effects, EGCG was shown to be protective in inflammatory bowel disease (IBD), a condition associated with barrier dysfunction. …”

Table_2_High Prevalence of Metallo-β-Lactamase-Producing Enterobacter cloacae From Three Tertiary Hospitals in China.xlsx by Yimei Cai (52714)

“…Notably, we identified the first NDM-1 and IMP-1 co-producing E. cloacae, carrying plasmids of several incompatibility (Inc) groups, including IncHI2, IncHI2A, and IncN. Most isolates showed decreased expression of ompC and/or ompF, and contained a broad distribution of ESBLs and AmpC β-lactamases. …”

Table_1_Physiological and Biomechanical Responses to Cross-Country Skiing in Varying Terrain: Low- vs. High-Intensity.docx by Trine M. Seeberg (5979200)

“…The terrain-dependent fluctuations did not differ between LI and HI for V.O2 (p = 0.50), whereas HR fluctuated less (p < 0.01) and displayed a time-dependent increase from Lap 2 to Lap 7 (7.8%-points, p > 0.01) during HI. …”

Table_2_Physiological and Biomechanical Responses to Cross-Country Skiing in Varying Terrain: Low- vs. High-Intensity.docx by Trine M. Seeberg (5979200)

“…The terrain-dependent fluctuations did not differ between LI and HI for V.O2 (p = 0.50), whereas HR fluctuated less (p < 0.01) and displayed a time-dependent increase from Lap 2 to Lap 7 (7.8%-points, p > 0.01) during HI. …”

Table_1_High Prevalence of Metallo-β-Lactamase-Producing Enterobacter cloacae From Three Tertiary Hospitals in China.xlsx by Yimei Cai (52714)

“…Notably, we identified the first NDM-1 and IMP-1 co-producing E. cloacae, carrying plasmids of several incompatibility (Inc) groups, including IncHI2, IncHI2A, and IncN. Most isolates showed decreased expression of ompC and/or ompF, and contained a broad distribution of ESBLs and AmpC β-lactamases. …”

Image 2_The green tea component (−)-epigallocatechin-3-gallate protects against cytokine-induced epithelial barrier damage in intestinal epithelial cells.tif by Rita Rosenthal (285303)

“…Among other beneficial effects, EGCG was shown to be protective in inflammatory bowel disease (IBD), a condition associated with barrier dysfunction. …”

Increased 14-3-3β and γ protein isoform expressions in parasitic eosinophilic meningitis caused by <i>Angiostrongylus cantonensis</i> infection in mice by Hung-Chin Tsai (673178)

“…</p><p>Mice were orally infected with 50 <i>A</i>. <i>cantonensis</i> L3 via an oro-gastric tube and sacrificed every week for 3 consecutive weeks after infection. …”

Image 1_The green tea component (−)-epigallocatechin-3-gallate protects against cytokine-induced epithelial barrier damage in intestinal epithelial cells.tif by Rita Rosenthal (285303)

“…Among other beneficial effects, EGCG was shown to be protective in inflammatory bowel disease (IBD), a condition associated with barrier dysfunction. …”

Table_3_Revealing the novel autophagy-related genes for ligamentum flavum hypertrophy in patients and mice model.docx by Peng Li (69518)

“…Using transmission electron microscopy, quantitative RT-PCR, Western blotting, and immunohistochemistry, we identified six hub ARGs in clinical specimens and bipedal standing (BS) mouse model.</p>Results<p>A total of 70 potential differentially expressed ARGs were screened, including 50 up-regulated and 20 down-regulated genes. …”

Image_1_Efficacy and safety of transarterial chemoembolization plus antiangiogenic- targeted therapy and immune checkpoint inhibitors for unresectable hepatocellular carcinoma with... by Jin-Kai Feng (11197404)

“…Purpose<p>This study aimed to assess the efficacy and safety of a triple therapy that comprises transarterial chemoembolization (TACE), antiangiogenic-targeted therapy, and programmed death-1 (PD-1) inhibitors in a real-world cohort of patients with unresectable hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT).…”

Data_Sheet_1_Socioeconomic disparities associated with mortality in patients hospitalized for COVID-19 in Colombia.pdf by Oscar Ignacio Mendoza Cardozo (14856355)

“…Finally, the odds of death from COVID-19 in hospitalized patients gradually decreased as the pandemic evolved. In conclusion, socioeconomic disparities were a major risk factor for mortality in patients hospitalized for COVID-19 in Colombia.…”

Image_2_Palmitic Acid Methyl Ester and Its Relation to Control of Tone of Human Visceral Arteries and Rat Aortas by Perivascular Adipose Tissue.jpeg by Ning Wang (108353)

“…These effects were abolished by XE991 (30 μM), but not 4-aminopyridine (2 mM) or NDGA (10 μM), a lipoxygenases inhibitor. The cytochrome P450 epoxygenase inhibitor 17-octadecynoic acid (ODYA 10 μM) and the soluble epoxide hydrolase inhibitor 12-(3-adamantan-1-ylureido)-dodecanoic acid (AUDA 10 μM) slightly decreased PAME relaxations. …”

Table_1_Revealing the novel autophagy-related genes for ligamentum flavum hypertrophy in patients and mice model.docx by Peng Li (69518)

“…Using transmission electron microscopy, quantitative RT-PCR, Western blotting, and immunohistochemistry, we identified six hub ARGs in clinical specimens and bipedal standing (BS) mouse model.</p>Results<p>A total of 70 potential differentially expressed ARGs were screened, including 50 up-regulated and 20 down-regulated genes. …”

Data_Sheet_1_Socioeconomic disparities associated with mortality in patients hospitalized for COVID-19 in Colombia.pdf by Oscar Ignacio Mendoza Cardozo (14856355)

“…Finally, the odds of death from COVID-19 in hospitalized patients gradually decreased as the pandemic evolved. In conclusion, socioeconomic disparities were a major risk factor for mortality in patients hospitalized for COVID-19 in Colombia.…”

Table_1_Lung Cancer Death Attributable to Long-Term Ambient Particulate Matter (PM2.5) Exposure in East Asian Countries During 1990–2019.DOCX by Xiaoxue Liu (649082)

“…<p>Background: Ambient particulate matter is a public health concern in East Asia as it contributes to a growing number of all-cause and cancer deaths. …”

Estimating the health and economic effects of the proposed US Food and Drug Administration voluntary sodium reformulation: Microsimulation cost-effectiveness analysis by Jonathan Pearson-Stuttard (780760)

“…</p><p>Methods and findings</p><p>We used a microsimulation approach of a close-to-reality synthetic population (US IMPACT Food Policy Model) to estimate CVD deaths and cases prevented or postponed, quality-adjusted life years (QALYs), and cost-effectiveness from 2017 to 2036 of 3 scenarios: (1) optimal, 100% compliance with 10-year reformulation targets; (2) modest, 50% compliance with 10-year reformulation targets; and (3) pessimistic, 100% compliance with 2-year reformulation targets, but with no further progress. …”

Image_1_Revealing the novel autophagy-related genes for ligamentum flavum hypertrophy in patients and mice model.tif by Peng Li (69518)

“…Using transmission electron microscopy, quantitative RT-PCR, Western blotting, and immunohistochemistry, we identified six hub ARGs in clinical specimens and bipedal standing (BS) mouse model.</p>Results<p>A total of 70 potential differentially expressed ARGs were screened, including 50 up-regulated and 20 down-regulated genes. …”