Analysis of Cargo Loading Modes and Capacity of an Electrically-Powered Active Carrier by Xiaoye Huo (3766630)

Causal Relationship between Obesity and Vitamin D Status: Bi-Directional Mendelian Randomization Analysis of Multiple Cohorts by Karani S. Vimaleswaran (149354)

“…</p> <h3>Methods and Findings</h3><p>We used information from 21 adult cohorts (up to 42,024 participants) with 12 BMI-related SNPs (combined in an allelic score) to produce an instrument for BMI and four SNPs associated with 25(OH)D (combined in two allelic scores, separately for genes encoding its synthesis or metabolism) as an instrument for vitamin D. …”

Data table of the Pathogen Box screen for inhibitors of mitochondrial O₂ consumption in <i>T</i>. <i>gondii</i> parasites. by Jenni A. Hayward (10063377)

“…Included are: the Pathogen Box plate and position of the test compounds; the MMV compound identification number and common name (where applicable); the Seahorse XFe96 plate well position and injection port from which the compound was injected during the assay (with compounds injected into Plate 1 indicated in green and compounds injected into Plate 2 in yellow); the mitochondrial OCR (mOCR) values immediately before and after compound injection (calculated by subtracting the non-mitochondrial OCR from the OCR values listed in Tab 2A-B; note that the post-drug values were obtained on the fourth measurement, approximately 18 min, after compound injection for all compounds except auranofin, for which we noticed a more gradual OCR decrease, and which was therefore calculated after ~40 min); the percent inhibition of mitochondrial OCR following compound injection (calculated from the difference between pre-compound injection and post-compound injection mOCR values); an indication of whether compounds met the >30% inhibition cut-off for hit compounds; and the chemical structures of all MMV compounds expressed in simplified molecular input line entry system (SMILES) notation. …”

Repetitive stress modulates loudness perception. by Ghattas Bisharat (20706928)

“…Mice exhibited increased perceptual boundaries during repeated stress, indicating a decreased loudness perception (<i>t</i> test, <i>p</i> = 1.2 × 10⁻⁰⁵, mean ± SE). …”

ATO inhibits migration in HUVECs. by Hong-yan Ge (783538)

“…(Original magnification:×100). A: a: Control group 0 hour; b: ATO 5.0 umol/L group 0 hour; c: Control group 48 h; d: ATO 5.0 umol/L group 48 h. …”

GRL-substrate interaction after half the substrate translocation. by Tomáš Kučera (807898)

“…<p>Panel A (Structure 50-0) shows a snapshot from the targeted MD simulation corresponding to the situation at time 0.84 ns of a 1.6-ns-long restraint period. …”

Image_3_Combining Organic Fertilizer With Controlled-Release Urea to Reduce Nitrogen Leaching and Promote Wheat Yields.JPEG by Xiuyi Yang (9648902)

“…Hence, the results suggest that the combination of 30–50% OF with CU synchronizes absorption with availability due to a period of increased N availability in soils and proved to be the best strategy for simultaneously increasing wheat production and reducing N leaching.…”

Image_2_Combining Organic Fertilizer With Controlled-Release Urea to Reduce Nitrogen Leaching and Promote Wheat Yields.JPEG by Xiuyi Yang (9648902)

“…Hence, the results suggest that the combination of 30–50% OF with CU synchronizes absorption with availability due to a period of increased N availability in soils and proved to be the best strategy for simultaneously increasing wheat production and reducing N leaching.…”

Image_1_Combining Organic Fertilizer With Controlled-Release Urea to Reduce Nitrogen Leaching and Promote Wheat Yields.JPEG by Xiuyi Yang (9648902)

“…Hence, the results suggest that the combination of 30–50% OF with CU synchronizes absorption with availability due to a period of increased N availability in soils and proved to be the best strategy for simultaneously increasing wheat production and reducing N leaching.…”

Cycles in RNA level fluctuations. by Zhongneng Xu (11177972)

“…<p>Blue line represents the demand for RNA activity (DRA), which is set to 50. Black curve represents the total RNA amount (TR) with a DRA of 50, and points on the line are values predicted by the model. …”

Data_Sheet_1_Mitochondrial Deficits With Neural and Social Damage in Early-Stage Alzheimer’s Disease Model Mice.docx by Afzal Misrani (10258750)

“…Mitochondrial dysfunction is thought to be an early event in the onset and progression of AD; however, the precise underlying mechanisms remain unclear. In this study, we investigated mitochondrial proteins involved in organelle dynamics, morphology and energy production in the medial prefrontal cortex (mPFC) and hippocampus (HIPP) of young (1∼2 months), adult (4∼5 months) and aged (9∼10, 12∼18 months) APP/PS1 mice. …”

Cif redirects CFTR from recycling endosomes to the lysosomal, degradative pathway. by Jennifer M. Bomberger (226715)

“…Plasma membrane, endosome and lysosomes designated in fractions based on Western blot of fraction for Na+/K+ ATPase, EEA-1 and Rab5a, and LAMP-1, respectively. …”

Scalable Production of a Multifunctional Protein (TSG-6) That Aggregates with Itself and the CHO Cells That Synthesize It by Dong-Ki Kim (847216)

Table_1_Canagliflozin alters the gut, oral, and ocular surface microbiota of patients with type 2 diabetes mellitus.docx by Limin Wang (87511)

“…</p>Clinical parameters<p>A significant decrease in fasting plasma glucose (8.22 ± 2.19 vs 6.87 ± 1.09 mmol/L), glycated serum protein [291.00 (264.00, 353.00) vs 275.00 (251.00, 342.50) μmol/L], hemoglobin A1c (7.39 ± 1.18 vs 7.12 ± 1.33%), body mass index (25.32 ± 2.99 vs 24.83 ± 2.95 kg/m²), systolic blood pressure (129.05 ± 17.51 vs 123.43 ± 14.82 mmHg), and urinary creatinine [158.40 (74.75, 219.15) vs 79.70 (56.25, 138.10) μmmol/kg] levels was noted after 30-day Cana monotherapy (P < 0.05).…”

Supplementary Material for: Systematic Review and Meta-Analysis of the Impact of Hypoxia on Infarcted Myocardium: Better or Worse? by Pang B. (5404793)

“…<b><i>Methods:</i></b> We conducted an electronic search of the PubMed, EMBASE, and Web of Science databases and extracted the outcomes of cardiac function, geometry, and hemodynamics. A random-effect model was applied when the I² value of greater than 50%. …”

Signature of Aberrant DNA Methylation in <i>MYC</i>-Induced T cell Lymphomas by Rene Opavsky (32415)

“…Only data for RLGS fragments that have been methylated in more than 50% of tumors are shown. Methylation data from the analysis of three sets of EGFP-positive and EGFP-negative thymocytes isolated from 21-d-old <i>EμSR-tTA;Teto-MYC;Teto-Cre;Rosa26LOXP^EGFP</i> mice are also shown (see text and <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.0030167#pgen-0030167-g002" target="_blank">Figure 2</a>).…”

DataSheet_1_Canagliflozin alters the gut, oral, and ocular surface microbiota of patients with type 2 diabetes mellitus.xls by Limin Wang (87511)

“…</p>Clinical parameters<p>A significant decrease in fasting plasma glucose (8.22 ± 2.19 vs 6.87 ± 1.09 mmol/L), glycated serum protein [291.00 (264.00, 353.00) vs 275.00 (251.00, 342.50) μmol/L], hemoglobin A1c (7.39 ± 1.18 vs 7.12 ± 1.33%), body mass index (25.32 ± 2.99 vs 24.83 ± 2.95 kg/m²), systolic blood pressure (129.05 ± 17.51 vs 123.43 ± 14.82 mmHg), and urinary creatinine [158.40 (74.75, 219.15) vs 79.70 (56.25, 138.10) μmmol/kg] levels was noted after 30-day Cana monotherapy (P < 0.05).…”

DataSheet_3_Canagliflozin alters the gut, oral, and ocular surface microbiota of patients with type 2 diabetes mellitus.xls by Limin Wang (87511)

“…</p>Clinical parameters<p>A significant decrease in fasting plasma glucose (8.22 ± 2.19 vs 6.87 ± 1.09 mmol/L), glycated serum protein [291.00 (264.00, 353.00) vs 275.00 (251.00, 342.50) μmol/L], hemoglobin A1c (7.39 ± 1.18 vs 7.12 ± 1.33%), body mass index (25.32 ± 2.99 vs 24.83 ± 2.95 kg/m²), systolic blood pressure (129.05 ± 17.51 vs 123.43 ± 14.82 mmHg), and urinary creatinine [158.40 (74.75, 219.15) vs 79.70 (56.25, 138.10) μmmol/kg] levels was noted after 30-day Cana monotherapy (P < 0.05).…”

DataSheet_2_Canagliflozin alters the gut, oral, and ocular surface microbiota of patients with type 2 diabetes mellitus.xls by Limin Wang (87511)

“…</p>Clinical parameters<p>A significant decrease in fasting plasma glucose (8.22 ± 2.19 vs 6.87 ± 1.09 mmol/L), glycated serum protein [291.00 (264.00, 353.00) vs 275.00 (251.00, 342.50) μmol/L], hemoglobin A1c (7.39 ± 1.18 vs 7.12 ± 1.33%), body mass index (25.32 ± 2.99 vs 24.83 ± 2.95 kg/m²), systolic blood pressure (129.05 ± 17.51 vs 123.43 ± 14.82 mmHg), and urinary creatinine [158.40 (74.75, 219.15) vs 79.70 (56.25, 138.10) μmmol/kg] levels was noted after 30-day Cana monotherapy (P < 0.05).…”

Fig 7 - by Abu Baker (12418905)

“…<p><b>A.</b> Images showing a Mitotracker Red CMXROS staining under phase contrast microscope after 24 h treatment of AbSvGNPs, abira, CtGNPs, and SvGNPs at IC-25, IC-50, and IC-75 concentration against DU145 cell lines. …”