L-glutamate concentration-response relationships of SmGluCl-1:SmGluCl-2.1 and SmGluCl-1:SmGluCl-3 hetero-oligomers in <i>Xenopus</i> oocytes. by Vanessa Dufour (421400)

“…Co-injection of <i>SmGluCl-1</i> cRNA with <i>SmGluCl-2.1</i> cRNA decreased the response to glutamate compared to oocytes injected with <i>SmGluCl-2.1</i> cRNA alone (P<0.05, paired-T test), suggesting that SmGluCl-1 is a GluCl subunit and can form a heteromeric receptor with SmGluCl-2.1. …”

ERDRP-0519 potently inhibits <i>de novo</i> RNA synthesis. by Robert M. Cox (8029568)

“…<p><b>A-F)</b> Purified recombinant WT MeV L-P complexes or complexes harboring the L_T776A or L_H589Y resistance mutations were incubated with either a 16-nt RNA template (A) and the represented NTPs to assess <i>de novo</i> RNA synthesis or a 16-nt RNA template (B), a 5’-phosphorylated 4-nt primer, and the represented NTPs to assess primer extension. …”

Single cell gene expression analysis demonstrates transcriptional variation in murine LT-HSCs. by Jason P. Glotzbach (216727)

“…Error bars represent standard deviations derived through bootstrapping over 100,000 iterations as previously described <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0021211#pone.0021211-Efron1" target="_blank">[50]</a>.…”

Image_1_Hybrid Nanoparticles as an Efficient Porphyrin Delivery System for Cancer Cells to Enhance Photodynamic Therapy.TIF by Letícia B. Silva (11447653)

“…<p>Photodynamic therapy (PDT) is a potential non-invasive approach for application in oncological diseases, based on the activation of a photosensitizer (PS) by light at a specific wavelength in the presence of molecular oxygen to produce reactive oxygen species (ROS) that trigger the death tumor cells. …”

Image_3_Hybrid Nanoparticles as an Efficient Porphyrin Delivery System for Cancer Cells to Enhance Photodynamic Therapy.TIF by Letícia B. Silva (11447653)

“…<p>Photodynamic therapy (PDT) is a potential non-invasive approach for application in oncological diseases, based on the activation of a photosensitizer (PS) by light at a specific wavelength in the presence of molecular oxygen to produce reactive oxygen species (ROS) that trigger the death tumor cells. …”

DataSheet1_Computational design of custom therapeutic cells to correct failing human cardiomyocytes.pdf by Andrew Tieu (14441499)

“…Using a genetic algorithm-based optimization approach, candidate cells were accepted if a root mean square error (RMSE) of less than 50% relative to healthy hCM was achieved for both action potential and calcium transient waveforms for the cell-treated HF cardiomyocyte, normalized to the untreated HF cardiomyocyte.…”

Data_Sheet_1_Interaction of energy and sulfur microbial diet and smoking status with polygenic variants associated with lipoprotein metabolism.PDF by Haeng Jeon Hur (6808157)

“…The risk alleles of CETP_rs708272 and ALDH1A2_rs588136 were linked to increased expression in the heart and decreased in the brain, respectively. …”

DataSheet_1_Genetic Screening for TLR7 Variants in Young and Previously Healthy Men With Severe COVID-19.pdf by Xavier Solanich (7447049)

“…Functional testing of this variant revealed decreased type I and II interferon responses in peripheral mononuclear blood cells upon stimulation with the TLR7 agonist imiquimod, confirming a loss-of-function effect.…”

DataSheet1_Computational design of custom therapeutic cells to correct failing human cardiomyocytes.pdf by Andrew Tieu (14441499)

“…Using a genetic algorithm-based optimization approach, candidate cells were accepted if a root mean square error (RMSE) of less than 50% relative to healthy hCM was achieved for both action potential and calcium transient waveforms for the cell-treated HF cardiomyocyte, normalized to the untreated HF cardiomyocyte.…”

Table_1_Post-silking Phosphorus Recycling and Carbon Partitioning in Maize Under Low to High Phosphorus Inputs and Their Effects on Grain Yield.DOCX by Chao Wang (146527)

“…Despite the higher P uptake with P fertilization above this threshold, the lack of additional plant growth and yield resulted in decreased P-use efficiency. Regardless of P application rates, P remobilization to the ear during the first half of the grain filling phase preferentially came from the stem (50–76%) rather than from leaves (30–44%), and with a greater proportion in the inorganic P (Pi) form over organic P fractions. …”

Profiling overall protein <i>O</i>-glycosylation pathway genes in <i>F. graminearum.</i> by Heeji Moon (17474719)

“…Sexual developments were categorized as discrete phenotypic traits and scored on a 4-point scale (a: no difference compared with wild-type, b: decreased number of perithecia and ascospore or delayed perithecia maturation or decreased number of discharged ascospores, c: no perithecia and ascospore formation or no ascospore discharge, e: essential genes). …”

Model prediction of the SPARTAC trial. by Changwang Zhang (716808)

“…<i>t</i>_<i>p</i> is the time between the initial infection and the <i>primary end point</i> (when density of CD4⁺ T cells decreases to 350 <i>cells</i>/<i>μl</i> or the start of long-term ART [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1004179#pcbi.1004179.ref028" target="_blank">28</a>]). …”

Palmitoylation inhibitors specifically impair ectodomain-dependent APP dimerization but not APP-CTF-dimerization. by Raja Bhattacharyya (3359186)

“…<p>A. Naïve CHO cells co-expressing APP_V5 and APP_HA were subjected to a co-IP assay in presence of DMSO (0 μg/ml) or increasing concentrations of cerulenin (25, 50 and 100 μg/ml). …”

Profiling overall protein <i>N</i>-glycosylation pathway genes in <i>F. graminearum.</i> by Heeji Moon (17474719)

“…Sexual developments were categorized as discrete phenotypic traits and scored on a 4-point scale (a: no difference compared with wild-type, b: decreased number of perithecia and ascospore or delayed perithecia maturation or decreased number of discharged ascospores, c: no perithecia and ascospore formation or no ascospore discharge, e: essential genes). …”

Investigating algal CO2 capture through screening of Qatari desert microalgae & cyanobacteria strains by Al Muraikhi, Mariam

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In-depth Analysis of Pedestrian Safety in the State of Qatar by Kharbeche, Mohamed

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Epidemiology of herpes simplex virus type 2 in sub-Saharan Africa: Systematic review, meta-analyses, and meta-regressions by Harfouche, Manale

“…Background: Herpes simplex virus type 2 (HSV-2) infection is a prevalent, sexually transmitted infection with a sizable disease burden that is highest in sub-Saharan Africa. …”
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DataSheet_2_Integral Projection Models and Sustainable Forest Management of Agave inaequidens in Western Mexico.pdf by Ignacio Torres-García (4579165)

“…Our study was performed in four well-conserved wild populations in Central Western Mexico, each population was sampled in a plot of about one hectare composed by 10 subplots 50 x 5 m (2500 m²). …”

Opening of Astrocytic Mitochondrial ATP-Sensitive Potassium Channels Upregulates Electrical Coupling between Hippocampal Astrocytes in Rat Brain Slices by Jiangping Wang (281901)

“…Activation of mitoK_ATP channel also decreased the latency time of the transjunctional currents by 50%. …”

Six-year changes in refraction and related ocular biometric factors in an adult Chinese population by Xiaotong Han (2920902)

“…</p><p>Conclusions</p><p>This study confirms a hyperopic shift in the elderly before 65 years old and a myopic shift thereafter. …”