Table 2_Proteome changes during in vitro culture adaptation of Toxoplasma gondii archetypal II and III field isolates.xlsx by Joachim Müller (265589)

“…Interestingly, differentially abundant proteins were clearly linked to phenotypic changes associated to in vitro adaptation: loss of ability to spontaneously form cysts at high passages and decreased expression of cyst and bradyzoite markers (BAG1, Enolase 1, and SRS35A), while culture adaptation was associated with increased abundance of recognized virulence factors such as GRA15, GRA16, TEEGR and NSM.…”

Image 4_Proteome changes during in vitro culture adaptation of Toxoplasma gondii archetypal II and III field isolates.tif by Joachim Müller (265589)

“…Interestingly, differentially abundant proteins were clearly linked to phenotypic changes associated to in vitro adaptation: loss of ability to spontaneously form cysts at high passages and decreased expression of cyst and bradyzoite markers (BAG1, Enolase 1, and SRS35A), while culture adaptation was associated with increased abundance of recognized virulence factors such as GRA15, GRA16, TEEGR and NSM.…”

hNGF WT and mutants bioactivity on <i>in vitro</i> differentiation of purified primary rat OPCs. by Francesca Malerba (161148)

“…Cell nuclei are marked with DAPI (blue). Scale bar: 50 μm. hNGF increases the percentage of undifferentiated NG2+ cells (left panels: in red) and decreases the percentage of O4+ pre-oligodendrocytes (right panels: in red), indicating that NGF inhibits OPC differentiation. …”

Table 3_Proteome changes during in vitro culture adaptation of Toxoplasma gondii archetypal II and III field isolates.xlsx by Joachim Müller (265589)

“…Interestingly, differentially abundant proteins were clearly linked to phenotypic changes associated to in vitro adaptation: loss of ability to spontaneously form cysts at high passages and decreased expression of cyst and bradyzoite markers (BAG1, Enolase 1, and SRS35A), while culture adaptation was associated with increased abundance of recognized virulence factors such as GRA15, GRA16, TEEGR and NSM.…”

DataSheet_1_Alterations of Gut Microbiome and Metabolite Profiles Associated With Anabatic Lipid Dysmetabolism in Thyroid Cancer.xls by Ganghua Lu (12750878)

“…</p>Methods<p>16S rRNA gene sequencing and an integrated LC–MS-based metabolomics approach were performed to obtain the components and characteristics of fecal microbiota and metabolites from 50 patients with TC and 58 healthy controls (HCs).…”

Image_1_Species-specific metabolome changes during salinity downshift in sub-Arctic populations of Mytilus edulis and M. trossulus.pdf by Inna M. Sokolova (3857770)

“…Taurine emerged as the dominant osmolyte, comprising over 50% of the total free amino acid pool, with aspartate and glycine contributing 15–30%. …”

Image_2_Neutrophil depletion in the pre-implantation phase impairs pregnancy index, placenta and fetus development.jpeg by Cristina Bichels Hebeda (5931599)

“…On gestational day 5.5, neutrophil depletion impaired the blastocyst implantation, as 50% of pregnant mice presented reduced implantation sites. …”

Trial sequential analysis. by Jiaxuan Wen (12531339)

“…Dexmedetomidine as opposed to midazolam achieved a shorter length of stay in ICU (MD = -2.25, 95%CI = -2.94, -1.57, p<0.0001), lower risk of delirium (RR = 0.63, 95%CI = 0.50, 0.81, p = 0.0002), and shorter duration of mechanical ventilation (MD = -0.83, 95%CI = -1.24, -0.43, p<0.0001). …”

Is the lady's-slipper orchid (<i>Cypripedium calceolus</i>) likely to shortly become extinct in Europe?—Insights based on ecological niche modelling by Marta Kolanowska (471074)

“…According to these analyses all the scenarios of future climate change will result in the total area of niches suitable for <i>C</i>. <i>calceolus</i> decreasing. Considering areas characterized by a suitability of at least 0.4 the loss of habitat will vary between ca. 30% and 63%. …”

Image 1_Proteome changes during in vitro culture adaptation of Toxoplasma gondii archetypal II and III field isolates.tif by Joachim Müller (265589)

“…Interestingly, differentially abundant proteins were clearly linked to phenotypic changes associated to in vitro adaptation: loss of ability to spontaneously form cysts at high passages and decreased expression of cyst and bradyzoite markers (BAG1, Enolase 1, and SRS35A), while culture adaptation was associated with increased abundance of recognized virulence factors such as GRA15, GRA16, TEEGR and NSM.…”

Video_6_Aging dysregulates neutrophil extracellular trap formation in response to HIV in blood and genital tissues.mp4 by Laura Moreno de Lara (12966254)

“…<p>Women acquire HIV through sexual transmission, with increasing incidence in women >50 years old. Identifying protective mechanisms in the female genital tract (FGT) is important to prevent HIV-acquisition in women as they age. …”

Image_3_Alterations of Gut Microbiome and Metabolite Profiles Associated With Anabatic Lipid Dysmetabolism in Thyroid Cancer.tif by Ganghua Lu (12750878)

“…</p>Methods<p>16S rRNA gene sequencing and an integrated LC–MS-based metabolomics approach were performed to obtain the components and characteristics of fecal microbiota and metabolites from 50 patients with TC and 58 healthy controls (HCs).…”

Effect of Epo on Beclin 1, LC3 and p62 expression in ileum of experimental NEC rats. by Yueyue Yu (437616)

“…<p>(A) IHC staining of Beclin 1 (Bec1), IF staining of LC3 and p62 in ileum sections of MF pups and experimental pups without or with Epo administration (–Epo vs. …”

The Effect of Garlic and Voluntary Exercise on Cardiac Angiogenesis in Diabetes: The Role of MiR-126 and MiR-210 by Roya Naderi (6098570)

“…On the other hand, there was a miR-210 expression increase in the myocardium of diabetic animals (p < 0.001). …”

Early CD8⁺-recovery independently predicts low probability of disease relapse but also associates with severe GVHD after allogeneic HSCT by Juha Ranti (5774918)

“…We found that CD8⁺ T-cell counts exceeding 50x10⁶/l as early as on day 28 post-transplantation correlated significantly with decreased relapse risk, with three-year relapse rates of 17.0% and 55.6% (P = 0.002), but were also associated with severe acute and chronic GVHD. …”

Selecting Populations for Non-Analogous Climate Conditions Using Universal Response Functions: The Case of Douglas-Fir in Central Europe by Debojyoti Chakraborty (784894)

“…In the present study, we analyzed the intraspecific variation in climate growth response of Douglas-fir planted within the non-analogous climate conditions of Central and continental Europe. With data from 50 common garden trials, we developed Universal Response Functions (URF) for tree height and mean basal area and compared the growth performance of the selected best performing populations with that of populations identified through a climate envelope approach. …”

The NAD⁺ that is spontaneously released from M-MSNs@NAD⁺ can not increase the intracellular NAD⁺ and ATP levels in H₂O₂-treat... by Heyu Chen (456225)

“…<p>(A) The concentration of NAD⁺ that was spontaneously released from the 50 µg/mL M-MSNs@NAD⁺ into the media. …”

Image_3_Positive Effects of Neutrophil Elastase Inhibitor (Sivelestat) on Gut Microbiome and Metabolite Profiles of Septic Rats.tif by Yali Sun (2099593)

“…</p>Results<p>Sivelestat administration significantly improved the survival of septic rats (80% vs 50%, P = 0.047). Microbiome analysis showed that the microbiota composition of rats in the CLP group was significantly disturbed, as potential pathogens such as Escherichia-Shigella and Gammaproteobacteria became dominant, and the beneficial microbiota represented by Lactobacillus decreased. …”

Image_1_Positive Effects of Neutrophil Elastase Inhibitor (Sivelestat) on Gut Microbiome and Metabolite Profiles of Septic Rats.tif by Yali Sun (2099593)

“…</p>Results<p>Sivelestat administration significantly improved the survival of septic rats (80% vs 50%, P = 0.047). Microbiome analysis showed that the microbiota composition of rats in the CLP group was significantly disturbed, as potential pathogens such as Escherichia-Shigella and Gammaproteobacteria became dominant, and the beneficial microbiota represented by Lactobacillus decreased. …”

N-cadherin localization changes during and after KCl depolarization. by Patricia T. Yam (478888)

“…<p>(<b>A</b>,<b>B</b>) During depolarization with 30-50 mM KCl, the proportion of synapses with N-cadherin puncta adjacent to the active zone increases, whereas the proportion of synapses with N-cadherin along the synaptic cleft decreases. n=3 experiments, ≥88 synapses per experiment, total of 315 synapses (178 and 137 synapses for the control and during KCl stimulation conditions respectively). * = p<0.05, ** = p<0.01, two-way ANOVA with matched values and Bonferroni post-test. …”