Table_3_Pro-Inflammatory Implications of 2-Hydroxypropyl-β-cyclodextrin Treatment.docx by Tom Houben (3185082)

“…The inflammatory and cholesterol-depleting effects of CD were first investigated in low-density lipoprotein receptor knockout (Ldlr^-/) mice that were transplanted with Npc1^nih or Npc1^wt bone marrow and were fed either regular chow or a high-fat, high-cholesterol (HFC) diet for 12 weeks, thereby creating an extreme model of lysosomal cholesterol-induced metabolic inflammation. …”

DataSheet_1_Pro-Inflammatory Implications of 2-Hydroxypropyl-β-cyclodextrin Treatment.docx by Tom Houben (3185082)

“…The inflammatory and cholesterol-depleting effects of CD were first investigated in low-density lipoprotein receptor knockout (Ldlr^-/) mice that were transplanted with Npc1^nih or Npc1^wt bone marrow and were fed either regular chow or a high-fat, high-cholesterol (HFC) diet for 12 weeks, thereby creating an extreme model of lysosomal cholesterol-induced metabolic inflammation. …”

Image_3_Effects of Allicin on Late Sodium Current Caused by ΔKPQ-SCN5A Mutation in HEK293 Cells.TIF by Yating Chen (6707360)

“…Application of Allicin 30 μM reduced the late sodium current (I_Na,L) of the Nav1.5 channel current encoded by ΔKPQ-SCN5A from 1.92 ± 0.12 to 0.65 ± 0.03 pA/pF (P < 0.01, n = 15), which resulted in the decrease of I_Na,L/I_Na,P (from 0.94% ± 0.04% to 0.32% ± 0.02%). …”

Image_7_Pro-Inflammatory Implications of 2-Hydroxypropyl-β-cyclodextrin Treatment.tif by Tom Houben (3185082)

“…The inflammatory and cholesterol-depleting effects of CD were first investigated in low-density lipoprotein receptor knockout (Ldlr^-/) mice that were transplanted with Npc1^nih or Npc1^wt bone marrow and were fed either regular chow or a high-fat, high-cholesterol (HFC) diet for 12 weeks, thereby creating an extreme model of lysosomal cholesterol-induced metabolic inflammation. …”

Table_4_Pro-Inflammatory Implications of 2-Hydroxypropyl-β-cyclodextrin Treatment.docx by Tom Houben (3185082)

“…The inflammatory and cholesterol-depleting effects of CD were first investigated in low-density lipoprotein receptor knockout (Ldlr^-/) mice that were transplanted with Npc1^nih or Npc1^wt bone marrow and were fed either regular chow or a high-fat, high-cholesterol (HFC) diet for 12 weeks, thereby creating an extreme model of lysosomal cholesterol-induced metabolic inflammation. …”

Video_3_Pro-Inflammatory Implications of 2-Hydroxypropyl-β-cyclodextrin Treatment.mov by Tom Houben (3185082)

“…The inflammatory and cholesterol-depleting effects of CD were first investigated in low-density lipoprotein receptor knockout (Ldlr^-/) mice that were transplanted with Npc1^nih or Npc1^wt bone marrow and were fed either regular chow or a high-fat, high-cholesterol (HFC) diet for 12 weeks, thereby creating an extreme model of lysosomal cholesterol-induced metabolic inflammation. …”

Effects of different production rates, penetrances and administration times of A3G^ΔVif on HIV growth curve. by Iraj Hosseini (184245)

“…<p>In all the simulations, 500,000 cells were inoculated by 1 ng 24 WT HIV input. (A–D) A3G^ΔVif with different production rates were administered right after inoculation. …”

mRNA Secondary Structures Can Explain Experimental Observations by Michael Hiller (11282)

“…<div><p>(A) A structural change explains exon skipping by the 25G->A mutation in the human <i>CFTR</i> exon 12<b>.</b> NI scores [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.0030204#pgen-0030204-b036" target="_blank">36</a>] for the wild-type (wt) and the 25G->A mutation (highlighted gray) indicate the strength of ESE (blue, positive score) and ESS (red, negative score) motifs. …”

Image_6_Pro-Inflammatory Implications of 2-Hydroxypropyl-β-cyclodextrin Treatment.tif by Tom Houben (3185082)

“…The inflammatory and cholesterol-depleting effects of CD were first investigated in low-density lipoprotein receptor knockout (Ldlr^-/) mice that were transplanted with Npc1^nih or Npc1^wt bone marrow and were fed either regular chow or a high-fat, high-cholesterol (HFC) diet for 12 weeks, thereby creating an extreme model of lysosomal cholesterol-induced metabolic inflammation. …”

Image_4_Pro-Inflammatory Implications of 2-Hydroxypropyl-β-cyclodextrin Treatment.tif by Tom Houben (3185082)

“…The inflammatory and cholesterol-depleting effects of CD were first investigated in low-density lipoprotein receptor knockout (Ldlr^-/) mice that were transplanted with Npc1^nih or Npc1^wt bone marrow and were fed either regular chow or a high-fat, high-cholesterol (HFC) diet for 12 weeks, thereby creating an extreme model of lysosomal cholesterol-induced metabolic inflammation. …”

Video_1_Pro-Inflammatory Implications of 2-Hydroxypropyl-β-cyclodextrin Treatment.mov by Tom Houben (3185082)

“…The inflammatory and cholesterol-depleting effects of CD were first investigated in low-density lipoprotein receptor knockout (Ldlr^-/) mice that were transplanted with Npc1^nih or Npc1^wt bone marrow and were fed either regular chow or a high-fat, high-cholesterol (HFC) diet for 12 weeks, thereby creating an extreme model of lysosomal cholesterol-induced metabolic inflammation. …”

Table_1_Condensed Tannins in White Clover (Trifolium repens) Foliar Tissues Expressing the Transcription Factor TaMYB14-1 Bind to Forage Protein and Reduce Ammonia and Methane Emis... by Marissa B. Roldan (7023566)

“…However, the transformation of white clover with the TaMYB14-1 transcription factor from Trifolium arvense has resulted in the production of CTs in leaves up to 1.2% of dry matter (DM). In this study, two generations of breeding elevated foliar CTs to >2% of DM. …”

Image_4_Effects of Allicin on Late Sodium Current Caused by ΔKPQ-SCN5A Mutation in HEK293 Cells.TIF by Yating Chen (6707360)

“…Application of Allicin 30 μM reduced the late sodium current (I_Na,L) of the Nav1.5 channel current encoded by ΔKPQ-SCN5A from 1.92 ± 0.12 to 0.65 ± 0.03 pA/pF (P < 0.01, n = 15), which resulted in the decrease of I_Na,L/I_Na,P (from 0.94% ± 0.04% to 0.32% ± 0.02%). …”

Video_5_Pro-Inflammatory Implications of 2-Hydroxypropyl-β-cyclodextrin Treatment.mov by Tom Houben (3185082)

“…The inflammatory and cholesterol-depleting effects of CD were first investigated in low-density lipoprotein receptor knockout (Ldlr^-/) mice that were transplanted with Npc1^nih or Npc1^wt bone marrow and were fed either regular chow or a high-fat, high-cholesterol (HFC) diet for 12 weeks, thereby creating an extreme model of lysosomal cholesterol-induced metabolic inflammation. …”

Video_4_Pro-Inflammatory Implications of 2-Hydroxypropyl-β-cyclodextrin Treatment.mov by Tom Houben (3185082)

“…The inflammatory and cholesterol-depleting effects of CD were first investigated in low-density lipoprotein receptor knockout (Ldlr^-/) mice that were transplanted with Npc1^nih or Npc1^wt bone marrow and were fed either regular chow or a high-fat, high-cholesterol (HFC) diet for 12 weeks, thereby creating an extreme model of lysosomal cholesterol-induced metabolic inflammation. …”

Table_5_Pro-Inflammatory Implications of 2-Hydroxypropyl-β-cyclodextrin Treatment.docx by Tom Houben (3185082)

“…The inflammatory and cholesterol-depleting effects of CD were first investigated in low-density lipoprotein receptor knockout (Ldlr^-/) mice that were transplanted with Npc1^nih or Npc1^wt bone marrow and were fed either regular chow or a high-fat, high-cholesterol (HFC) diet for 12 weeks, thereby creating an extreme model of lysosomal cholesterol-induced metabolic inflammation. …”

Data_Sheet_1_Water in Alkali Aluminosilicate Glasses.DOCX by Robert Balzer (8846273)

“…The density of hydrous glasses linearly decreased with water content above 1 wt%, consistent with the partial molar volume of H₂O of 12 cm³/mol. …”

Loss of the capacity to induce IL-8 in <i>H. pylori</i> recovered from rhesus monkeys is associated with changes in the gene encoding CagY, an essential protein in the T4SS. by Roberto M. Barrozo (383765)

“…<p>(A–E) <i>H. pylori</i> was isolated from five rhesus macaques up to 14 months after experimental infection with <i>H. pylori</i> WT J166. Individual colonies were co-cultured with AGS cells, and ELISA was used to measure IL-8 levels, which were normalized to the WT J166 positive control. …”

Time-resolved UV-visible spectroscopy of bodipy-based materials by F Cucinotta (7836197)

“…The first set of materials is characterised by green luminescence that, as the dye loading increases from 1% to 50%, shows a decrease in quantum yields from 0.22 to 0.05 and a reduction of the excited state lifetime. …”

Igf signaling is required for cardiomyocyte proliferation during zebrafish heart development. by Ying Huang (53474)

“…E. A significant decrease (***<i>p</i><0.0001) in cardiomyocyte proliferation was detected in embryos treated with NVP-AEW541.…”