Data_Sheet_1_Microevolution and Adaptive Strategy of Psychrophilic Species Flavobacterium bomense sp. nov. Isolated From Glaciers.docx by Qing Liu (20889)

The Fitness Landscapes of <i>cis</i>-Acting Binding Sites in Different Promoter and Environmental Contexts by Ryan K. Shultzaberger (24946)

Cell growth, cell viability and programmed cell death following oseltamivir treatment. by Joana T. de Oliveira (718565)

Data Sheet 1_Characterization and immunoprotection of thioredoxin reductase TrxB knockout mutant of Salmonella Enteritidis.pdf by Siping Zhu (607538)

“…We also observed a significant decrease in the expression of virulence-related genes in the trxB-knockout mutant. …”

Aspirin treatment inhibits osteoclast activities. by Takayoshi Yamaza (67506)

“…(D) RANKL-induced osteoclastogenesis was partially blocked by aspirin treatment at 50 µg/ml as seen a significantly decreased number of TRAP-positive osteoclasts in aspirin treated group (ASP 50). …”

Table_1_Hydrostatic Pressure Regulates the Volume, Aggregation and Chondrogenic Differentiation of Bone Marrow Derived Stromal Cells.docx by Paola Aprile (9990584)

Altered mRNA Editing and Expression of Ionotropic Glutamate Receptors after Kainic Acid Exposure in Cyclooxygenase-2 Deficient Mice by Luca Caracciolo (221279)

Data_Sheet_1_Astrocyte-Mediated Neuromodulatory Regulation in Preclinical ALS: A Metadata Analysis.PDF by Kathleen Jordan (6090041)

Significant Reductions in Mortality in Hospitalized Patients with Systemic Lupus Erythematosus in Washington State from 2003 to 2011 by Louisa B Goss (757328)

“…We found a significant decrease in annual hospital mortality over the study period [odds ratio(OR): 0.92 per year, 95% CI 0.88-0.96, P<0.001]. …”

Changes of the normalized volume V/V₀ in glioblastoma cell lines in response to sucrose- and inositol-substituted solutions of different osmolalities (LHS and RHS column... by Simon Memmel (518138)

“…Each data point represents the mean ± SE of 50–120 individual cells. Continuous curves in <i>A</i> show best least-square fits of the Lúcio-model <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0087052#pone.0087052-Lcio1" target="_blank">[50]</a> to the data. …”

Construction of ORF48 deletion mutants using the BAC16 system. by Beatriz H. S. Veronese (19486051)

“…(C) Analysis of BAC16-ORF48del VS WT BAC16. Deletion of the ORF48 coding region (1.2kb) results in a decreased size of a band from 25,693bp to 24,484bp, as indicated by red arrows. …”

Myogenesis and associated genes evaluated by CTNNA2 knock-down. by Adeel Malik (23840)

“…CTNNA2 expression was decreased in CTNNA2 knock-down cells. However, MYOG expression was similar in the CTNNA2_wt and CTNNA2_kd cells<sub>.…”

Female mice missing one <i>TCF8</i> allele gain weight more readily. by Jessica N. Saykally (368303)

“…<p>Mice were weaned to (<b>A</b>) a diet high in fat (60%) or (<b>B</b>) regular chow diet, and body weights (g) of female <i>TCF8 +/−</i> (black line) or WT (gray line) mice were recorded weekly as indicated. n = 8–34 mice per group, with the number of mice decreasing due to sacrifices at 2 and 3 months. …”

Characterization of primary identified SNVs. by Bernd Timmermann (190778)

“…(D) BMPR1A mutations show decreased signaling acitivity. Activity of wt mBMPR1A, mBMPR1A E502G and mBMPR1A W487R was determined in C2C12 cells using a SMAD-responsive Luciferase reporter gene assay. …”

Supplementary Material for: The P2X7 Receptor Contributes to the Development of the Exacerbated Inflammatory Response Associated with Sepsis by Santana P.T. (3632560)

“…<b><i>Results:</i></b> P2X7KO mice showed significantly increased survival 7 days after CLP (30% compared to 60% in WT animals) accompanied by an overall attenuated inflammatory response, with decreased cell recruitment to the peritoneum, no or limited increases in the levels of NO and proinflammatory cytokines (IL-1β, IL-6, IL-12, IL-17, and IL-4), reduced peritoneal cell apoptosis, and less pronounced lung infiltration and morphological changes. …”

Knockdown of E2A promotes colon cancer cell growth. by Ao Huang (508797)

“…GAPDH was used as loading control; (B) and (D) Cells with downregulated E2A expression (SW480/shE2A, Caco-2/shE2A) showed higher cell proliferation rate than that of the negative control (SW480/shNC, Caco-2/shNC) and wild type (SW480/WT, Caco-2/WT) cells; (C) and (E) Parental cells (SW480/shE2A, Caco-2/shE2A) were co-transfected with E12 or E47 plasmid (SW480/shE2A_E12 and SW480/shE2A_E47; Caco-2/shE2A_E12 and Caco-2/shE2A_E47) to restore E2A expression. …”

FGF19-mediated regulation of liver protein expression resolved by quantitative proteomics. by Vittoria Massafra (613864)

“…<p>(A) Schematic representation of the experimental outline to determine the hepatic proteomic profile of mice treated with FGF19 or Veh for 12 h. (n = 3) (B) Frequency plot of proteins identified in vehicle-treated Wt mice based on their total log2 heavy/light normalized ratio. …”

Excessive Astrocyte-Derived Neurotrophin-3 Contributes to the Abnormal Neuronal Dendritic Development in a Mouse Model of Fragile X Syndrome by Qi Yang (108283)

Tissue-specific regulation of <i>UBP1b</i> by siRNA854. by Andrea D. McCue (184831)

CD8⁺ T cells are not regulated by a PD-1-dependent mechanism in chronic <i>T</i>. <i>cruzi</i> infection. by Angela D. Pack (5954858)