Decreases in muscle size, muscle force, and TB mass in 3-mo Lmna^HSA-cko mice. by Lei Xiong (334812)

Density Functional Study on Compounds to Accelerate the Electron Capture Decay of ⁷Be by Akira Yoshida (392232)

“…Thus, the decay can be accelerated by changing the chemical or physical conditions. A previous study reported a 1.1–1.5% reduction in the half-life of ⁷Be encapsulated in C₆₀ compared with ⁷Be metal. …”

IL-17A inhibits apoptosis of OCPs. by Hao Tang (44155)

IL-17A promotes RANKL-stimulated osteoclastogenesis. by Hao Tang (44155)

Inhibition of autophagy attenuates IL-17A-mediated osteoclastogenesis. by Hao Tang (44155)

Lysine 50 of Tat regulates expression of C5, CRLF2, APBA1, and BDNF genes. by Loreto Carvallo (4167607)

“…<p>THP-1Tat-Flag and THP-1Tat K50ATat-Flag cell lines (generated from independent experiments described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0179882#pone.0179882.g005" target="_blank">Fig 5</a>) were differentiated to macrophages with PMA for 24 and 48 hours. …”

Activation of NMDA receptors with D-serine obviously limited the decrease of p-CREB in the hippocampus of the surviving LPS-treated mice. by Shuibing Zhang (4336402)

Treatment with con-G showed improved neurological scoring and decreased peri-infarct Ca²⁺ microdeposits. by Rashna Balsara (714796)

Nicotine decreased Akt phosphorylation in SK-BR-3 cells. by Masanori A. Murayama (5774585)

Juvenile demyelination induces a loss of functional autapses. by Sara Hijazi (21656615)

“…Cuprizone-treated mice show a significant decrease in the percentage of cells showing an autaptic response (<i>Fisher’s exact test; *p = 0.0173</i>). …”

DataSheet1_The antimicrobial peptide Esc(1-21)-1c increases susceptibility of Pseudomonas aeruginosa to conventional antibiotics by decreasing the expression of the MexAB-OprM effl... by Carolina Canè (17274244)

(A) Decreasing CaMKII activity by KN-93 (high-3 µmol/L, low-0.5 µmol/L), AIP (high-10 µmol/L, low-2 µmol/L), or decreasing calmodulin activity by W-7 (high-50 µmol/L, low-20 µmol/L) decreases spontaneous AP firing rate (n = 10 for each drug), cAMP (n = 4 for each drug) and ATP (n = 5 for each drug). by Yael Yaniv (162548)

Synthesis and Activity of a Novel Autotaxin Inhibitor–Icodextrin Conjugate by Natalie Fisher (1860283)

“…The conjugate inhibits autotaxin activity (IC₅₀ = 0.86 ± 0.13 μg mL^–1) and reduces cell migration. …”

Requirement of NF-κB activation for cytokine-mediated reductions in TEER. by Paul R. Clark (714064)

Intracellular Delivery of Bioactive Molecules using Light-Addressable Nanocapsules by Kimberly A. D. Gregersen (2241349)

“…We demonstrate this method with the intracellular release of the second messenger IP₃ in CHO-M1 cells and report that calcium responses from the cells changed from a sustained increase to a transient spike when the average number of IP₃ released is decreased below 50 molecules per nanocapsule. …”

DataSheet1_Trained hypertensive rats exhibit decreased transcellular vesicle trafficking, increased tight junctions’ density, restored blood-brain barrier permeability and normaliz... by Vanessa B. Candido (14670266)

DataSheet1_Calmodulin mutations affecting Gly114 impair binding to the NaV1.5 IQ-domain.docx by Malene Brohus (840080)

“…The impact was most severe at low and intermediate Ca²⁺ concentrations (up to 4 µM) resulting in more than a 50-fold reduction in Na_V1.5 binding affinity, and a smaller 1.5 to 11-fold reduction at high Ca²⁺ concentrations (25–400 µM). …”

IC₅₀ of indole alkaloid against alpha-glucosidase [26]. by Atikarn Janthongkaw (17020498)

Concentration of DRS-B2 and [W/F]³-DRS-B2 that inhibits 50% of cell growth (GI₅₀) extracted from Fig 12. by Célia Dos Santos (306471)

Integration of Segmented Ion Fractionation and Differential Ion Mobility on a Q‑Exactive Hybrid Quadrupole Orbitrap Mass Spectrometer by Sibylle Pfammatter (3226209)

“…However, the FAIMS interface has not been available on older generation Orbitrap mass spectrometers such as the Q-Exactive. Here, we report the integration of the FAIMS Pro device with embedded electrical and gas connections to a Q-Exactive HF mass spectrometer. …”