THRα/β EC₅₀ values and selectivity of test compounds. by Xuan G. Luong (9761423)

Downregulation of G9a induces autophagy and decreases tumorigenicity in neuroblastoma cells. by Xiao-Xue Ke (626989)

Kylo-0603’s EC50 & tissue levels. by Xueqin lu (22250795)

Predicting Vulnerabilities of North American Shorebirds to Climate Change by Hector Galbraith (636637)

Results of sensitivity analysis of risk categorization for shorebird species. by Hector Galbraith (636637)

Results of predicted change in extinction risk to shorebird species based on climate change. by Hector Galbraith (636637)

Ustekinumab trough concentration are shown by responder status and anti-ustekinumab antibody (A) Patients with negative anti-ustekinumab antibody had significantly higher drug trou... by Hsien-Yi Chiu (799936)

The Impact of Prophylactic Dexamethasone on Nausea and Vomiting after Thyroidectomy: A Systematic Review and Meta-Analysis by Zhenhong Zou (645858)

“…The meta-analysis demonstrated a significant decrease in the incidence of PONV (RR 0.52, 95% CI 0.43 to 0.63, <i>P</i><0.00001), the need for rescue anti-emetics (RR 0.42, 95% CI 0.30 to 0.57, <i>P</i><0.00001), post-operative pain scores (WMD –1.17, 95% CI –1.91 to –0.44, <i>P</i> = 0.002), and the need for rescue analgesics (RR 0.65, 95% CI 0.50–0.83, <i>P</i> = 0.0008) in patients receiving dexamethasone compared to placebo, with or without concomitant antiemetics. …”

Trend of temperature decrease in thermogradient freezer during the night from 7:00 P.M. to 5:00 A.M. by Alireza Hasanfard (13919335)

Propofol induced cell death and decreased mitochondrial membrane potential in a concentration- and time-dependent manner. by Chisato Sumi (3521705)

Image_1_Samm50 Promotes Hypertrophy by Regulating Pink1-Dependent Mitophagy Signaling in Neonatal Cardiomyocytes.TIF by Ran Xu (316855)

“…We first found that Samm50 is a key positive regulator of cardiac hypertrophy, for western blot and real-time quantitative PCR detection revealed Samm50 was downregulated both in pressure-overload-induced hypertrophic hearts and Ang II-induced cardiomyocyte hypertrophy. …”

Table_1_Samm50 Promotes Hypertrophy by Regulating Pink1-Dependent Mitophagy Signaling in Neonatal Cardiomyocytes.XLSX by Ran Xu (316855)

“…We first found that Samm50 is a key positive regulator of cardiac hypertrophy, for western blot and real-time quantitative PCR detection revealed Samm50 was downregulated both in pressure-overload-induced hypertrophic hearts and Ang II-induced cardiomyocyte hypertrophy. …”

Table_2_Samm50 Promotes Hypertrophy by Regulating Pink1-Dependent Mitophagy Signaling in Neonatal Cardiomyocytes.XLSX by Ran Xu (316855)

“…We first found that Samm50 is a key positive regulator of cardiac hypertrophy, for western blot and real-time quantitative PCR detection revealed Samm50 was downregulated both in pressure-overload-induced hypertrophic hearts and Ang II-induced cardiomyocyte hypertrophy. …”

Initial treatment regimen. by Shivani Patel (4742748)

“…Hedgehog inhibition (HHI) with vismodegib or sonidegib induces a 50–60% response rate. Long-term toxicity includes muscle spasms and weight loss leading to dose decreases. …”

Patients baseline characteristics. by Shivani Patel (4742748)

“…Hedgehog inhibition (HHI) with vismodegib or sonidegib induces a 50–60% response rate. Long-term toxicity includes muscle spasms and weight loss leading to dose decreases. …”

Overall survival. by Shivani Patel (4742748)

“…Hedgehog inhibition (HHI) with vismodegib or sonidegib induces a 50–60% response rate. Long-term toxicity includes muscle spasms and weight loss leading to dose decreases. …”

Progression-free survival by treatment. by Shivani Patel (4742748)

“…Hedgehog inhibition (HHI) with vismodegib or sonidegib induces a 50–60% response rate. Long-term toxicity includes muscle spasms and weight loss leading to dose decreases. …”

Maintenance regimen and adverse event management. by Shivani Patel (4742748)

“…Hedgehog inhibition (HHI) with vismodegib or sonidegib induces a 50–60% response rate. Long-term toxicity includes muscle spasms and weight loss leading to dose decreases. …”

BCC-specific survival. by Shivani Patel (4742748)

“…Hedgehog inhibition (HHI) with vismodegib or sonidegib induces a 50–60% response rate. Long-term toxicity includes muscle spasms and weight loss leading to dose decreases. …”

Potent Half-Sandwich Iridium(III) Anticancer Complexes Containing C^∧N‑Chelated and Pyridine Ligands by Zhe Liu (77240)

“…The monodentate py ligands blocked hydrolysis; however, antiproliferative studies showed that all the Ir compounds are highly active toward A2780, A549, and MCF-7 human cancer cells. In general the introduction of an electron-donating group (e.g., Me, NMe₂) at specific positions on the pyridine ring resulted in increased antiproliferative activity, whereas electron-withdrawing groups (e.g., COMe, COOMe, CONEt₂) decreased anticancer activity. …”