Cytotoxicity (as of %Control) IC₅₀ value (mean ±SD in µM) of the tested compounds vs. positive controls Cisplatin and doxorubicin against other malignancy’ cell lines ad... by MohammedBashar Al-Qazzan (22439236)

Introducing the 4‑Phenyl-1,2,3-Triazole Moiety as a Versatile Scaffold for the Development of Cytotoxic Ruthenium(II) and Osmium(II) Arene Cyclometalates by Christoph A. Riedl (3593534)

“…Herein we report the synthesis, anticancer potency <i>in vitro</i>, biomolecule interaction, and preliminary mode of action studies of a series of cyclometalated 1,2,3-triazole-derived ruthenium­(II) (<b>2a</b>–<b>e</b>) and osmium­(II) (<b>3a</b>–<b>e</b>) organometallics of the general form [(η⁶-<i>p</i>-cym)­RuCl­(κ²-C^N-L)] with varying substituents in postion 1 of the 1,2,3-triazole moiety. …”

<i>btuE</i> expression results in decreased intracellular ROS. by Felipe A. Arenas (23050)

The functional half-life of WNV decreases in the presence of virus-specific antibody. by Kimberly A. Dowd (129927)

Effects of increasing temperature and, CO₂ on quality of litter, shredders, and microorganisms in Amazonian aquatic systems by Renato Tavares Martins (4634317)

“…We hypothesized that simulated climate change (warming and elevated CO₂) would: i) decrease leaf-litter quality, ii) decrease survival and leaf breakdown by shredders, and iii) increase microbial leaf breakdown and fungal biomass. …”

Scatter plots showing the relationships of GC-IPL/VD ratio with age. by Woo-Hyuk Lee (8496168)

Intake and digestibility during two digestibility trials (1: 20–28 d; 2: 50–56 d) of dairy calves fed different additives in the starter feed (n = 15). by Luisa F. L. Salazar (6664121)

Discovery of Novel Substituted <i>N</i>‑(4-Amino-2-chlorophenyl)-5-chloro-2-hydroxybenzamide Analogues as Potent Human Adenovirus Inhibitors by Jimin Xu (2208961)

“…Notably, among these derivatives, compound <b>15</b> showed improved anti-HAdV activity (IC₅₀ = 0.27 μM), significantly decreased cytotoxicity (CC₅₀ = 156.8 μM), and low <i>in vivo</i> toxicity (maximum tolerated dose = 150 mg/kg in hamster) as compared with niclosamide, supporting its further <i>in vivo</i> efficacy studies for the treatment of HAdV infections.…”

S1 Data - by Woo-Hyuk Lee (8496168)

“…</p><p>Conclusions</p><p>GC-IPL thickness and macular VD showed a tendency to decrease beginning in the 50s age group and the GC-IPL/VD ratio was significantly increased in the 60s age group. …”

The %change in GABA level had a trend correlation with MEP amplitude in the left sensorimotor area (R = −0.43002, R2 = 0.1849, t = 1.844717, p = 0.082575). by Hiroyuki Matsuta (13250169)

Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach by Sneha P. (3926957)

“…<div><p>Maturity-onset diabetes of the young type 3 (MODY3) is a non-ketotic form of diabetes associated with poor insulin secretion. …”

Quantification of <i>ATP5B</i> mRNA and β-F1-ATPase protein expression shows decreased protein translation in obesity. by Lee Tran (2106961)

Pretreatment of Huh-7.5.1 cells with PF-429242 results in a dose-dependent decrease in intracellular DENV-2 NS1 protein abundance and a 3-log decrease in extracellular viral titer. by Anastasia Hyrina (3860455)

Decreasing cell adhesion decreases [Ca²⁺]_i oscillation frequency. by Charles Godbout (540424)

Decreased Aβ oligomer immunoreactivity in APPxPS1 mice after treatment with hNGFP61S/R100E: polyclonal pAb A11 antibody. by Simona Capsoni (161132)

Metformin lotion decreases collagen III levels in the wounded skin of rats after 10 days of wound healing. by Jianying Zhang (256508)

Orsay virus infection of the <i>lin-8(n2731</i>) synMuv A mutant induces a Muv phenotype indicative of decreased synMuv B gene activity, and 2 different synMuv B mutants produce 50–100× less Orsay virus RNA. by Ashwin Seetharaman (615458)

Increased levels of PPARγ and decreased levels of adiponectin in thymus from rats administered cocaine for 7 days. by Kana Unuma (283272)

Metformin lotion decreases collagen III levels in the wounded skin of rats after 10 days of wound healing. by Jianying Zhang (256508)

Occurrences of the hemoglobin safety composite endpoint (hemoglobin decrease of ≥40 g/L or ≥40% versus baseline or hemoglobin <50 g/L or blood transfusion) by G6PD genotype in the... by Zul Premji (215008)