Effects of DIDS on forskolin-induced I_SC in the absence and presence of Uzara or ouabain. by Jörg D. Schulzke (354049)

“…Application of 10 µM forskolin induced an I_SC that was reduced in the presence of Uzara (50 µg/ml) and ouabain (100 µM). Under all three conditions, application of DIDS (100 µ µM) caused a pronounced transient increase in I_SC, presumably due to an increase in intracellular Ca²⁺. …”

Mycolactone induces IL-1β secretion by activating the NLRP3/1 inflammasome pathway. by M. Foulon (9873663)

“…<p>Three known inhibitors of the inflammasome pathway implicated in the secretion of IL-1β were added to LPS-stimulated BMDM cultures in the presence of mycolactone (3 ng/mL) or CPPD (20 μg/mL). <b>A.</b> The addition of 2.5 mM or 25 mM N-acetyl-L-cysteine (NAC) decreased and totally abolished IL-1β secretion, respectively, in the presence of either mycolactone or CPPD. …”

The PI3K/Akt- and NO-related pathways contribute to EPC tube formation affected by oxLDL. by Feng-Yen Lin (143413)

“…<p>(A and B) EPCs were treated for 2 hours with 0–50 μg/mL oxLDL, then eNOS and Akt activation (phosphorylation) was analyzed by Western blot. …”

Effect of TRPV4-mediated activation of SK3 channels on membrane potential, Vm. by Jonathan Berrout (555482)

“…</b> Effect of TRPV4 activation with GSK101 (50 nM) leading to membrane hyperpolarization of Vm (decreased RFU), as expected for SK3 and BK activation. …”

SPARC-mediated SLUG expression and promotion of melanoma cell migration is PI3K/AKT dependent. by Nina Fenouille (149658)

“…(<b>C</b>) <i>Expression of Myr-AKT protects from SLUG decrease after SPARC depletion:</i> 501mel cells were infected with a control empty adenovirus (AdCMV) or with adenovirus encoding the constitutively active mutant Myr-HA-AKT1 (AdAKT^ca) and transfected 6 hours later with 50 nM siCTRL or siSPARC for 3 days. …”

Additional file 2 of Nup133 and ERα mediate the differential effects of hyperoxia-induced damage in male and female OPCs by Donna Elizabeth Sunny (9301250)

“…Changes in nuclear envelope proteins in OPCs post hyperoxia. (A) Western blot analysis of male and female OPCs with anti-Nup-50 and anti-Lamin B1 antibodies under normal (3%O2) conditions and post 24 h 80%O2 treatment, showing a significant decrease in expression in the male OPCs. …”

Golgi-160 was essential for agglutination level of the GA and GDNF improved it. by Chuan-Xi Tang (6274154)

“…<p>(A and B) Immunofluorescence and GA agglutination level analysis in the control group, with or without 50 ng/ml GDNF treatment. …”

ATF4 knockdown in the ADRP retinas reduces overall ER stress response (N = 4). by Yogesh Bhootada (408443)

“…The T17M ATF4^+/- retinas were the only group with a significant decrease in peIF2a (P<0.01 as compared to T17M retinas) and increased GADD34 protein levels (<i>P</i><0.05 for all groups). …”

Data from: Effect of macronutrients and fiber on postprandial glycemic responses and meal glycemic index and glycemic load value determinations by Huicui Meng (12708455)

“…</p> <p>Results: Adding carbohydrate to the standard white-bread challenge increased glucose AUCi (P < 0.0001), measured meal GI (P = 0.0066), and mean GL (P < 0.0001). Adding protein (50 g only) decreased glucose AUCi (P = 0.0026), measured meal GI (P = 0.0139), and meal GL (P = 0.0140). …”

Assessment of transcriptome associated with endothelium activation and blood-brain barrier integrity. by Nana O. Wilson (399957)

Sensitivity analysis. by Daniela S Santurio (21030812)

“…For each patient, a constant 50% reduction in each activation mechanism was simulated and the mean reduction in IL6 peak was calculated (reference scenario, black dots, same values as shown in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1012908#pcbi.1012908.g008" target="_blank">Fig 8A</a> fourth panel); this analysis was then repeated by increasing ( + ) and decreasing (–) each parameter in 50% increments.…”

Cell cycle indexes of oNSCs in the developing OE show selective defects in <i>BAF155</i>cKO mutants. by Christina Bachmann (3111933)

“…Scale bars = 25 μm (A) and 50 μm (G–J).</p>…”

Sensitivity of SbV-resistant <i>L. panamensis</i> parasites to edelfosine. by Rubén E. Varela-M (326741)

“…(F) Edelfosine treatment led to a dramatic decrease and amelioration in parasite-induced nose thickness and damage, as shown by photographs from drug-free control and edelfosine-treated hamsters. …”

Evaluation and risk communication of effects of alcohol exposure on disposable procedure masks and portable air purifiers by Yo Ishigaki (11052900)

Recombination DNA repair was impaired in <i>BRIT1</i>-deficient spermatocytes. by Yulong Liang (241535)

“…Value shown here represents the mean±SD from ∼50 late zygotene spermatocytes for each genotype. …”

Activation of the <i>PC3</i> Transgene Accelerates the Differentiation of 1–5-d-Old Adult-Generated Dentate Gyrus Stem and Progenitor Cells by Stefano Farioli-Vecchioli (256006)

“…</p> <p>(B) The number of putative stem cells (type-1; BrdU/GFAP/nestin-positive) decreased about 50% in mice with activated <i>PC3</i> transgene.…”

Bacterial adherence and invasion assays. by Guijing Yu (2921838)

Figure 5 by Parvin Shahrestani (260210)

Aluminum toxicity reduces the nutritional efficiency of macronutrients and micronutrients in sugarcane seedlings by Carolina Eggers Borges (10398678)

“…The root system was the most affected, with a decrease in growth of up to 60%. Aluminum reduced the use efficiency of nutrient in decreasing order: Ca (69%)> N (60%)> K (59%)> Mg (50%)> S (49%)> P (40%). …”

Table_2_Association mapping uncovers maize ZmbZIP107 regulating root system architecture and lead absorption under lead stress.xlsx by Fengxia Hou (13861286)