DataSheet_1_A cyclic peptide-based PROTAC induces intracellular degradation of palmitoyltransferase and potently decreases PD-L1 expression in human cervical cancer cells.docx by Yu-Ying Shi (15975992)

“…Introduction<p>Our previous research has found that degradation of palmitoyltransferase in tumor cells using a linear peptide PROTAC leads to a significant decrease in PD-L1 expression in tumors. …”

<b>Diroximel fumarate acts through Nrf2 to attenuate methylglyoxal-induced nociception in mice and decrease ISR activation in DRG neurons</b> by Muhammad Saad Yousuf (20745168)

Effects of seed priming on CAT under salt stress at different growth stages. by Xiaoqian Guo (3684295)

Effects of seed priming on POD under salt stress at different growth stages. by Xiaoqian Guo (3684295)

Effects of seed priming on SOD activity of sorghum plants under salt stress at different growth stages. by Xiaoqian Guo (3684295)

Identification of Gut Microbiota Biomarker Genera Distinguishing Wild and Captive Animals (A) Top 50 discriminative genera selected by random forest classifier, ranked by mean decrease accuracy. by Lin Xu (94491)

Correlation between hub genes and 50 hallmark signaling pathways. by Jiyong Zhang (2498740)

Sensitivity analysis for IC₅₀ and <i>ε</i>_max as a function of measurement time. by Hope Murphy (8843516)

The IC50 value of Tan in normal esophageal HET-1A cells. by Dong Yang (141041)

Assessment of exoprotein concentration in a 50-mL culture of MH96. by Marion Schoof (11999106)

Experimental outline. by Melissa A. MacIver (12850566)

Immunofluorescence of select extracellular matrix (ECM) components. by Melissa A. MacIver (12850566)

“…<p>Matched sections from traditional histology (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0269571#pone.0269571.g008" target="_blank">Fig 8</a>) were assessed via immunofluorescence for aggrecan, Collagen Type II, and Collagen Type X. …”

While NA formation is substrate stiffness independent, maturation is influenced considerably by stiffness. by Kailas Shankar Honasoge (17108745)

Hematoxylin and eosin (H&E) staining, Sirius Red staining, and Oil Red staining of liver tissues from mice in each group after 8 weeks of treatment with either vehicle or Kylo-0603... by Xueqin lu (22250795)

Host population bottlenecks decrease microbiome diversity. by Michael Ørsted (5926028)

FTY720 decreased viability, proliferation, and motility and induced apoptosis in human hepatoblastoma cells. by Laura L. Stafman (6577184)

“…<p>(A) Following 24 hours of treatment with FTY720, the viability of HuH6 cells measured using the alamarBlue cell viability assay was significantly decreased (LD₅₀ = 8.4 μM, p ≤ 0.05). …”

E₅₀ values. by Junxia Zhou (14381598)

The injectable contraceptives depot medroxyprogesterone acetate and norethisterone enanthate substantially and differentially decrease testosterone and sex hormone binding globulin... by Chanel Avenant (409756)

“…Both contraceptives substantially decreased, from D0 to 25W, the total testosterone [DMPA-IM D0 0.560, 25W 0.423 nmol/L, -24.3% (p < 0.0001); NET-EN D0 0.551, 25W 0.253 nmol/L, -54.1%, (p < 0.0001)], SHBG [DMPA-IM D0 45.0, 25W 32.7 nmol/L, -29.8% (p < 0.0001); NET-EN D0 50.2, 25W 17.6 nmol/L, -65.1% (p < 0.0001)], and calculated free testosterone levels [DMPA-IM D0 6.87, 25W 5.38 pmol/L, -17.2% (p = 0.0371); NET-EN D0 6.00, 25W 3.70, -40.0% (p < 0.0001)]. …”

Fig 3 - by Yan Shu (441370)

Predicting pattern diversity decreases as a function of and . by Selim Haj Ali (21222613)

“…(a) and (b): Average negative predictive value for and , respectively for and . …”