Dose response analysis of active compounds identified in the primary HTS. by Kishore Polireddy (153876)

“…<p>(a) ABCB6 expressing cells showed dose dependent decrease in median channel fluorescence (representing PPIX fluorescence) in response to benzethonium chloride, verteporfin, and to a lesser extent piperlongumine. …”

Synaptic facilitation between tail SNs and MNs following sensitizing tail shocks declined during aging. by Andrew T. Kempsell (738294)

“…C) Monosynaptic facilitation between tail SNs and MNs following sensitizing tail shocks decreased during aging. A single AP evoked in tail SNs by 50 ms injected current resulted in a monosynaptic EPSP in tail MNs in mature (n = 14) and aged II (n = 13) preparations. …”

Secondary screening of primary hits reveals four true <i>p27^Kip1</i> inhibitors. by Brandon J. Walters (301187)

“…Dose-dependent luciferase inhibition (black) and alamar blue inhibition (blue) of each compound (n = 3, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0091173#pone-0091173-t001" target="_blank">Table 1</a> lists the calculated IC₅₀’s). …”

QuantitativeStrayAssignment.R from High dispersal rates in hybrids drive expansion of maladaptive hybridization by Samuel L. Bourret (13997720)

“…Hybridization between native and invasive species, a major cause of biodiversity loss, can spread rapidly even when hybrids have reduced fitness. …”

SOIL PHYSICAL ATTRIBUTES BEFORE AND AFTER MANAGEMENT UNDER SOWING FORWARD SPEED by Jorge W. Cortez (5312624)

“…The medium harrowing operation has higher sD and the ideal forward sowing speed range to mitigate this effect would be 5.0 to 7.0 km h−1. Moreover, it also presents a higher amount of macropores in the 0.20–0.30 m layer. …”

The public health system and the place of autism by Vanini Mandaj (16029441)

“…Final Considerations: although the Psychosocial Care Network for Children is the reference in the region, it is known that this facility alone cannot meet all needs of individuals with autism spectrum disorder. A service network coordinated according to patient’s individual needs and the region's reality would ensure their expected rights, decrease public spending, and enable these users to occupy not only one but many places in society.…”

Ndk contributes to phagosome maturation arrest. by Jim Sun (367834)

“…In the bottom panel dotted circles indicate the position of Ndk-beads, while the red fluorescent signal (PKH) shows the location of BSA-beads and a significant decrease of dextran colocalization with distant PKH-BSA-beads. …”

Formation and Diffusivity Characterization of Supported Lipid Bilayers with Complex Lipid Compositions by Lisa Simonsson (1454506)

“…The concept is used to investigate the diffusivity of lissamine rhodamine B 1,2-dihexadecanoyl-<i>sn</i>-glycero-3-phosphoethanolamine (rhodamine–DHPE) in SLBs made from complex lipid compositions, revealing a decrease in diffusivity by a factor of 2 when the cholesterol content was increased from 0% to 50%. …”

Analysis of NIST Monoclonal Antibody Reference Material Glycosylation Using the LC–MS/MS-Based Glycoproteomic Approach by Jingfu Zhao (3113421)

“…The glycan structure with the highest abundance was FA2, with a relative abundance of 52% in sample A and 38% in sample B. …”

Depressive symptoms are associated with blunted reward learning in social contexts by Lou Safra (553574)

“…<div><p>Depression is characterized by a marked decrease in social interactions and blunted sensitivity to rewards. …”

Autonomic regulation of heart rate during specific dynamic action associated with digestion in the bullfrog Lithobates catesbeianus by Débora Claësson (12844042)

“…In addition to the withdrawal of vagal tone, digestion was also associated with an increase in the heart rate upon double-blockade (i.e., the combination of atropine and propranolol) from a fasting value of 44.5 ± 0.9 to 50.8 ± 1.9 min-1 at 33 hours. …”

Intracellular chloride measurements by Wallace B Thoreson (5462)

“…An example of the reduction in MEQ fluorescence, indicating an increase in intracellular [Cl], produced by application of 12.1 mM Kto a cone. C. A greater decrease in MEQ fluorescence was produced by application of 69.9 mM K. …”

Oosthuizen et al. Data.pdf by Tasha Oosthuizen (19200784)

“…When the night light originated remotely from a corner of the room, activity levels decreased by more than 50%, whereas under direct ALAN from above the cages, there was a 75% decrease in activity. …”

The effect of loss of combinations of PAPs on the phenotype of <i>Salmonella</i>. by Helen E. McNeil (8190873)

“…Data presented is the time taken for the fluorescence to decrease by 25% +/- SE. (Data for 10% and 50% drop can be seen in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1008101#ppat.1008101.s011" target="_blank">S1 Table</a>) <b>B</b>. …”

Correlational learning rule for regulation of vestibular synapse strength by cerebellar inhibition: transfer of VOR gain from cerebellar cortex to brainstem. by John R. W. Menzies (361198)

“…During training the cerebellum has learnt to produce an inhibitory input modulated in phase with the vestibular input, leading to cancellation which produces a 50% gain decrease (since and , a weight requires ). …”

Functional Lung Imaging during HFV in Preterm Rabbits by Jordan Thurgood (123527)

“…Whilst ventilated at fixed pressures, each animal was ventilated at frequencies of 1, 3, 5 and 10 Hz. A 50% decrease in delivered tidal volume was measured at 10 Hz compared to 1 Hz, yet at the higher frequency a 500% increase in minute activity was measured. …”

Substrate binding specificity of purified OpuAC. by Justina C. Wolters (207763)

“…The inhibition experiments with proline and carnitine show a decrease in the ΔF_max at increased concentrations of inhibitor, which is caused by the high concentrations of inhibitor (see panel A and B). …”

Loss of layer V pyramidal neurons of motor cortex. by Paolo d’Errico (494029)

“…Values are expressed as mean ± SEM. Scale bars: 5 mm in A; 50 µm in C.</p>…”

Data_Sheet_1_Drug-Tolerant Idling Melanoma Cells Exhibit Theory-Predicted Metabolic Low-Low Phenotype.docx by Dongya Jia (3897142)

“…L/L metabolism is unfavorable for tumor growth, yet supports successful cell division at ~50% rate. Thus, L/L drug-tolerant idling cells are a reservoir for accumulating mutations responsible for relapse, and it should be considered as a target subpopulation for improving MAPKi outcomes in melanoma treatment.…”

The adhesion genes are activated by TAp63β but not by ΔNp63β in Caski cells. by Youcef Ben Khalifa (203743)

“…<p>(A) Real-time PCR performed in Caski cells infected with recombinant adenoviruses expressing GFP compared to TAp63β (upper panel) or ΔNp63β (lower panel) at increasing m.o.i. (20, 50 and 100). …”