Figure 5 from KDM6 Demethylases Contribute to EWSR1::FLI1-Driven Oncogenic Reprogramming in Ewing Sarcoma by Elisabet Figuerola-Bou (22618659)

“…<p>KDM6A KO decreases Ewing sarcoma tumor growth. <b>A,</b> Colony formation assay of KDM6A KO cells (sgRNA#1 and sgRNA#2) compared with parental cells and sgCTRL in A-673. …”

Pharmacological blockade of K_ATP channels negates the hippocampal synaptic and neuronal protection afforded by ketones. by Do Young Kim (131974)

“…<p>(A) Changes in PS amplitude (as % of baseline) during or after drug application under different experimental conditions. …”

Tapered Multiblock Copolymers Based on Farnesene and Styrene: Impact of Biobased Polydiene Architectures on Material Properties by Christian Wahlen (1768180)

“…The one-pot, tapered copolymer approach was used to synthesize series of tri- (ABA) and pentablock (ABABA) copolymers of styrene (A) and β-farnesene (B), varying the polydiene volume fraction between 0.50 and 0.68, respectively. …”

Meta data of <i>In vitro</i> and <i>In vivo</i> experiments. by Mohammad Abdullah Taher (18691717)

“…The extract showed broad-spectrum antibacterial activity, with strongest inhibition against <i>Pseudomonas aeruginosa</i> (19 mm) and <i>Salmonella typhi</i> (19 mm), though 30–50% less potent than standard antibiotics. In antidiarrheal testing, 400 mg/kg dose reduced diarrheal episodes by 58.06% compared to control, while in analgesic assay it decreased writhing by 59.18%. …”

ENPP1 Affects Insulin Action and Secretion: Evidences from <em>In Vitro</em> Studies by Rosa Di Paola (158545)

“…<div><p>The aim of this study was to deeper investigate the mechanisms through which ENPP1, a negative modulator of insulin receptor (IR) activation, plays a role on insulin signaling, insulin secretion and eventually glucose metabolism. …”

CdpR directly binds to <i>pqsH-cdpR</i> intergenic region and regulates <i>pqsH</i> expression. by Jingru Zhao (2633782)

“…<b>(F)</b> The production of PQS was decreased in the <i>cdpR</i> mutant. Lane 1 contains 50 ng of PQS. …”

The core model with an additional intracellular feedback is superior and gene expression upon downregulation of IRF family members. by Katharina Robichon (8445099)

“…(<b>H</b>) Gene expression upon decreased <i>IRF8</i> expression. Huh7.5 cells were incubated with 50 nM siRNA directed against <i>IRF8</i> (red), against <i>IRF8</i> and <i>IRF2</i> (lilac) or non-targeting control (blue) for 24 hours, and then treated with 500 U/ml IFNα. …”

Data_Sheet_1_Increased fruit intake is associated with reduced risk of depression: evidence from cross-sectional and Mendelian randomization analyses.docx by Zhaoqi Yan (11322876)

“…Fruit intake was also associated with a decreased risk of neuroticism traits related to depression, including feeling lonely (OR = 0.82, 95% CI = 0.74–0.90; p = 2.91E-05), feeling miserable (OR = 0.79, 95% CI = 0.72–0.87; p = 2.35E-06), feeling fed-up (OR = 0.75, 95% CI = 0.68–0.83; p = 2.78E-08), irritable mood (OR = 0.89, 95% CI = 0.79–0.99; p = 0.03), and neuroticism (OR = 0.85, 95% CI = 0.76–0.96; p = 9.94E-03). …”

Expression of RIO kinases is associated with EGFR and Akt activity in GBM cells. by Renee D. Read (268044)

“…(G) Neurosphere cultures treated for 24 hours with DMSO or indicated inhibitors. P110 inhibitors: 50 µM LY294002, 1 µM BEZ-235, 2 µM GDC-0941 <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003253#pgen.1003253-Raynaud1" target="_blank">[71]</a>, 2 µM PI-103 <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003253#pgen.1003253-Raynaud1" target="_blank">[71]</a>. …”

Plasma MicroRNAs as Potential Noninvasive Biomarkers for In-Stent Restenosis by Meijiao He (666387)

“…</p><p>Methods</p><p>This retrospective, observational single-centre study was conducted at the cardiovascular department of a tertiary hospital centre in the north of China. …”

RNA-seq transcriptomics analysis in human tissue culture cells reveals changes in the expression levels of over 100 nucleolar mRNAs after PAX9 knockdown. by Katherine I. Farley-Barnes (9258036)

“…Of these, 812 mRNAs had a decreased fold change (≤ -2) and 184 of those mRNAs code for proteins designated as nucleolar in at least one of three databases [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1008967#pgen.1008967.ref050" target="_blank">50</a>–<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1008967#pgen.1008967.ref052" target="_blank">52</a>]. …”

Enhanced drug resistance suppression by serum-stable micelles from multi-arm amphiphilic block copolymers and tocopheryl polyethylene glycol 1000 succinate by Lei He (143930)

“…<p><b>Aim:</b> To develop a robust drug-delivery system using multi-arm amphiphilic block copolymers for enhanced efficacy in cancer therapy.…”

Data_Sheet_2_Probiotics and Synbiotics Addition to Bama Mini-Pigs' Diet Improve Carcass Traits and Meat Quality by Altering Plasma Metabolites and Related Gene Expression of Offspr... by Qian Zhu (191342)

“…<p>This study evaluated the effects of maternal probiotics and synbiotics addition on several traits and parameters in offspring. A total of 64 Bama mini pigs were randomly allocated into the control (basal diet), antibiotic (50 g/t virginiamycin), probiotics (200 mL/day probiotics), or synbiotics (500 g/t xylo-oligosaccharides and 200 mL/day probiotics) group and fed with experimental diets during pregnancy and lactation. …”

Data_Sheet_1_Probiotics and Synbiotics Addition to Bama Mini-Pigs' Diet Improve Carcass Traits and Meat Quality by Altering Plasma Metabolites and Related Gene Expression of Offspr... by Qian Zhu (191342)

“…<p>This study evaluated the effects of maternal probiotics and synbiotics addition on several traits and parameters in offspring. A total of 64 Bama mini pigs were randomly allocated into the control (basal diet), antibiotic (50 g/t virginiamycin), probiotics (200 mL/day probiotics), or synbiotics (500 g/t xylo-oligosaccharides and 200 mL/day probiotics) group and fed with experimental diets during pregnancy and lactation. …”

Image_2_An Analysis Based on Japonica Rice Root Characteristics and Crop Growth Under the Interaction of Irrigation and Nitrogen Methods.png by Zhuoqian Wang (9012881)

“…From full heading to maturity stages, N2 could promote root growth, LAD, and CGR under AWD to a greater extent than those under the other treatments. …”

6MWT results. by Imane Salmam (21485704)

“…Notably, all studies assessing the 6-minute walk test (6MWT) reported reduced distances, consistently falling below the 50^th percentile of normative values. …”

Flowchart of selected studies. by Imane Salmam (21485704)

“…Notably, all studies assessing the 6-minute walk test (6MWT) reported reduced distances, consistently falling below the 50^th percentile of normative values. …”

Antagonism of mGluR5 or Erk signaling reduces induction of epileptiform activity in TSC2^+/− CA3 hippocampus. by Wyatt B. Potter (367463)

“…<p>(a) Representative traces of WT and TSC2^+/− slices following DHPG treatment (50 µM, 30 min) and in the presence and absence of drug. …”

Image_1_An Analysis Based on Japonica Rice Root Characteristics and Crop Growth Under the Interaction of Irrigation and Nitrogen Methods.jpg by Zhuoqian Wang (9012881)

“…From full heading to maturity stages, N2 could promote root growth, LAD, and CGR under AWD to a greater extent than those under the other treatments. …”

Platelet depletion impairs host defense against acute <i>P</i>. <i>aeruginosa</i> pulmonary infection in mice. by Lei Yue (276252)

“…<p>(A, B, C, D) Platelets were activated after <i>P</i>. …”