Contrasting Size Dependence of Photochemical Lifetimes of Polypropylene and Expanded Polystyrene Microplastics in Surface Waters by Ariana Patterson (22764051)

“…However, a power relationship with an exponent of approximately 0.5 between PP dissolution and SA:V provided a significantly better fit, suggesting that non-SA-controlled processes may limit PP photodissolution. …”

Design and Synthesis of Novel Epigenetic Inhibitors Targeting Histone Deacetylases, DNA Methyltransferase 1, and Lysine Methyltransferase G9a with <i>In Vivo</i> Efficacy in Multip... by Obdulia Rabal (124515)

“…The corresponding epigenetic functional cellular responses are observed: histone-3 acetylation, DNA hypomethylation, and decreased histone-3 methylation at lysine-9. These chemical probes, multitarget epigenetic inhibitors, were validated against the multiple myeloma cell line MM1.S, demonstrating promising <i>in vitro</i> activity of <b>12a</b> (CM-444) with GI₅₀ of 32 nM, an adequate therapeutic window (>1 log unit), and a suitable pharmacokinetic profile. …”

Impact of age on sharing of top 5000 TCRβ clones. by Sarah A. Johnson (11355817)

Study area (a), location of 52 sediment collection devices (b) and photograph of one of the collection devices in the field, western USA. by Andrew Kulmatiski (833256)

Serum cholesterol concentrations in hyperthyroid cats and euthyroid controls. by Molly A. Bechtold (18794251)

IGF-1 downregulates MMP8 and reduces collagenase activity in cultured THP-1 macrophages. by Patricia Snarski (22305205)

The stable isotope method applied in this study is sensitive to detect the expected differences in V_PDH/V_CS with physiologic alterations in these fluxes, and... by Aviva Rabin-Court (6832373)

“…<p>(A) Glutamine in the physiologic range (0–10 mM) does not significantly affect the measured V_PDH/V_CS in MC38 or YUMM1.7 cells. n = 4 replicates per condition, with comparisons by ANOVA with Bonferroni’s multiple comparisons test. …”

Expression of CRYAB in normal and tumor tissue samples across different cancer types. by Rasool Saghaleyni (10526301)

Design and Synthesis of Novel Epigenetic Inhibitors Targeting Histone Deacetylases, DNA Methyltransferase 1, and Lysine Methyltransferase G9a with <i>In Vivo</i> Efficacy in Multip... by Obdulia Rabal (124515)

“…The corresponding epigenetic functional cellular responses are observed: histone-3 acetylation, DNA hypomethylation, and decreased histone-3 methylation at lysine-9. These chemical probes, multitarget epigenetic inhibitors, were validated against the multiple myeloma cell line MM1.S, demonstrating promising <i>in vitro</i> activity of <b>12a</b> (CM-444) with GI₅₀ of 32 nM, an adequate therapeutic window (>1 log unit), and a suitable pharmacokinetic profile. …”

Design and Synthesis of Novel Epigenetic Inhibitors Targeting Histone Deacetylases, DNA Methyltransferase 1, and Lysine Methyltransferase G9a with <i>In Vivo</i> Efficacy in Multip... by Obdulia Rabal (124515)

“…The corresponding epigenetic functional cellular responses are observed: histone-3 acetylation, DNA hypomethylation, and decreased histone-3 methylation at lysine-9. These chemical probes, multitarget epigenetic inhibitors, were validated against the multiple myeloma cell line MM1.S, demonstrating promising <i>in vitro</i> activity of <b>12a</b> (CM-444) with GI₅₀ of 32 nM, an adequate therapeutic window (>1 log unit), and a suitable pharmacokinetic profile. …”

Design and Synthesis of Novel Epigenetic Inhibitors Targeting Histone Deacetylases, DNA Methyltransferase 1, and Lysine Methyltransferase G9a with <i>In Vivo</i> Efficacy in Multip... by Obdulia Rabal (124515)

“…The corresponding epigenetic functional cellular responses are observed: histone-3 acetylation, DNA hypomethylation, and decreased histone-3 methylation at lysine-9. These chemical probes, multitarget epigenetic inhibitors, were validated against the multiple myeloma cell line MM1.S, demonstrating promising <i>in vitro</i> activity of <b>12a</b> (CM-444) with GI₅₀ of 32 nM, an adequate therapeutic window (>1 log unit), and a suitable pharmacokinetic profile. …”

Design and Synthesis of Novel Epigenetic Inhibitors Targeting Histone Deacetylases, DNA Methyltransferase 1, and Lysine Methyltransferase G9a with <i>In Vivo</i> Efficacy in Multip... by Obdulia Rabal (124515)

“…The corresponding epigenetic functional cellular responses are observed: histone-3 acetylation, DNA hypomethylation, and decreased histone-3 methylation at lysine-9. These chemical probes, multitarget epigenetic inhibitors, were validated against the multiple myeloma cell line MM1.S, demonstrating promising <i>in vitro</i> activity of <b>12a</b> (CM-444) with GI₅₀ of 32 nM, an adequate therapeutic window (>1 log unit), and a suitable pharmacokinetic profile. …”

Image5_Non-ammoniagenic proliferation and differentiation media for cultivated adipose tissue.JPEG by S. Hubalek (16638537)

“…In this study, the ammonium sensitivity of these cells was investigated by introducing ammonium chloride, which was found to inhibit their proliferation when above 5 mM and their adipogenic differentiation when above 2 mM. …”

Initial placements distributions, conditional on field. by Sergey V. Popov (6719075)

Basic information about the Twitter datasets. by Yen-Shao Chen (18264587)

Relative expression (fold-change) of immune genes in LPS-stimulated peritoneal macrophages. by Chaiwat Monmai (6377270)

Effects of CFAMs on the proteins associated with NF-κB and MAPK pathways in RAW264.7 cells. by Chaiwat Monmai (6377270)

Effects of various concentrations of <i>Codium fragile</i> extracts. by Chaiwat Monmai (6377270)

Coumarin-Annelated Regioisomeric Heptahelicenes: Influence of Helicity on Excited-State Properties and Chiroptical Properties by Arindam Mukhopadhyay (1961227)

Relative expression (fold-change) of immune genes in mitogen-stimulated splenic lymphocytes. by Chaiwat Monmai (6377270)