Table_1_Caspase-8 Inhibition Prevents the Cleavage and Degradation of E3 Ligase Substrate Receptor Cereblon and Potentiates Its Biological Function.doc by Liang Zhou (85586)

“…<p>Cereblon (CRBN), a substrate receptor of cullin 4-RING E3 ligase (CRL4), mediates the ubiquitination and degradation of constitutive substrates and immunomodulatory drug-induced neo-substrates including MEIS2, c-Jun, CLC1, IKZF1/3, CK1α, and SALL4. …”

Pathogenic implications for autoimmune mechanisms derived by comparative eQTL analysis of CD4⁺ versus CD8⁺ T cells by Silva Kasela (817613)

“…Most remarkably, we identify a common missense variant in <i>IL27</i>, associated with type 1 diabetes that results in decreased functional activity of the protein and reduced expression levels of downstream <i>IRF1</i> and <i>STAT1</i> in CD4⁺ T cells only. …”

Presentation_1_Inhibition of Lung Tumor Development in ApoE Knockout Mice via Enhancement of TREM-1 Dependent NK Cell Cytotoxicity.pdf by Yong Sun Lee (6852212)

“…Knockdown of ApoE expression in lung cancer cells and B16F10 cells also decreased cancer cell growth and metastasis. …”

Presentation_1_Inhibition of Lung Tumor Development in ApoE Knockout Mice via Enhancement of TREM-1 Dependent NK Cell Cytotoxicity.pdf by Yong Sun Lee (6852212)

“…Knockdown of ApoE expression in lung cancer cells and B16F10 cells also decreased cancer cell growth and metastasis. …”

Data_Sheet_1_GCN2-Like Kinase Modulates Stress Granule Formation During Nutritional Stress in Trypanosoma cruzi.PDF by Amaranta Muniz Malvezzi (8717763)

“…Upon nutritional deprivation, the polysomes decreased more than in TcK1 depleted line. However, eIF2α is still phosphorylated in TcK1 depleted line, as in wild type parasites. eIF2α phosphorylation increased at longer incubations times, but KO parasites showed less accumulation of ribonucleoprotein granules containing ATP-dependent RNA helicase involved in mRNA turnover (DHH1) and Poly-A binding protein (PABP1). …”

Table1_Structural changes in silicate melt: A record from high-field strength elements in the Himalayan Cenozoic leucogranites.xlsx by Li-E. Gao (14518886)

“…When the melt’s Zr/Hf and Nb/Ta ratio passes 20 and 5, respectively, NBO/T, M/F, and A/CNK first decrease and then increase; A/NK and C/NK first decrease and then become nearly constant; Na/K first becomes nearly constant and then increases. …”

Table_1_Exploring gene signatures and regulatory networks in a rat model of sciatica: implications and validation in neuropathic pain.DOCX by Mu Xu (594466)

“…Background<p>Sciatica (neuropathic pain [NP]) is a common disease characterized by pain from radiation along the sciatic nerve. …”

U2 small nuclear RNA auxiliary factor 2, transcriptionally activated by the transcription factor Dp-1/E2F transcription factor 1 complex, enhances the growth and aerobic glycolysis... by Yuguo Li (628076)

“…Both TFDP1 and E2F1 could bind to the promoter of <i>U2AF2</i> and exert a synergistic activating effect on <i>U2AF2</i> transcription. …”

Quantitative real-time PCR for mRNA expression in CsA-treated HRE cells. by Gyu-Tae Shin (5819249)

Cysteine protease inhibitor E₆₄ increased the clearance of the bacteria on the ocular surface in infected WT mouse but not in SP-D KO mice. by Zhiyong Zhang (44058)

“…<i>aureus</i> (10⁷ CFUs/eye) in infected WT and SP-D KO mice in the presence or absence of 10 nM of cysteine protease inhibitor (E₆₄). The CFUs of bacteria were significantly decreased (p<0.05) in the tear fluid of the infected WT mice in the presence of E₆₄ compared to its absence at both 3 and 6 h after infection. …”

Emergent codes in student open responses to the open-ended question “<i>How do you think you studied differently for this open-note exam compared to how you would study for a close... by Emily P. Driessen (13267665)

Image_2_Rbfox1 Is Expressed in the Mouse Brain in the Form of Multiple Transcript Variants and Contains Functional E Boxes in Its Alternative Promoters.jpg by Sonia Casanovas (8799128)

“…<p>The RNA-binding protein RBFOX1 is an important regulator of neuron development and neuronal excitability. Rbfox1 is a dosage-sensitive gene and in both mice and humans, decreased expression of Rbfox1 has been linked to neurodevelopmental disorders. …”

Tuberous Sclerosis Complex 1 Regulates dE2F1 Expression during Development and Cooperates with RBF1 to Control Proliferation and Survival by Ting-Chiu Hsieh (243481)

“…<div><p>Previous studies in <em>Drosophila melanogaster</em> have demonstrated that many tumor suppressor pathways impinge on Rb/E2F to regulate proliferation and survival. Here, we report that Tuberous Sclerosis Complex 1 (TSC1), a well-established tumor suppressor that regulates cell size, is an important regulator of dE2F1 during development. …”

Image_4_Rbfox1 Is Expressed in the Mouse Brain in the Form of Multiple Transcript Variants and Contains Functional E Boxes in Its Alternative Promoters.jpg by Sonia Casanovas (8799128)

“…<p>The RNA-binding protein RBFOX1 is an important regulator of neuron development and neuronal excitability. Rbfox1 is a dosage-sensitive gene and in both mice and humans, decreased expression of Rbfox1 has been linked to neurodevelopmental disorders. …”

Image_3_Rbfox1 Is Expressed in the Mouse Brain in the Form of Multiple Transcript Variants and Contains Functional E Boxes in Its Alternative Promoters.jpg by Sonia Casanovas (8799128)

“…<p>The RNA-binding protein RBFOX1 is an important regulator of neuron development and neuronal excitability. Rbfox1 is a dosage-sensitive gene and in both mice and humans, decreased expression of Rbfox1 has been linked to neurodevelopmental disorders. …”

Image_1_Rbfox1 Is Expressed in the Mouse Brain in the Form of Multiple Transcript Variants and Contains Functional E Boxes in Its Alternative Promoters.jpg by Sonia Casanovas (8799128)

“…<p>The RNA-binding protein RBFOX1 is an important regulator of neuron development and neuronal excitability. Rbfox1 is a dosage-sensitive gene and in both mice and humans, decreased expression of Rbfox1 has been linked to neurodevelopmental disorders. …”

Table_1_Rbfox1 Is Expressed in the Mouse Brain in the Form of Multiple Transcript Variants and Contains Functional E Boxes in Its Alternative Promoters.pdf by Sonia Casanovas (8799128)

“…<p>The RNA-binding protein RBFOX1 is an important regulator of neuron development and neuronal excitability. Rbfox1 is a dosage-sensitive gene and in both mice and humans, decreased expression of Rbfox1 has been linked to neurodevelopmental disorders. …”

<i>S. boulardii</i> Fails to Hold Its Cell Wall Integrity against Nonpathogenic <i>E. coli</i>: Are Probiotic Yeasts Losing the Battle? by Satyajit Lenka (10290092)

“…When experiments are repeated with lipopolysaccharide-depleted <i>E. coli</i> and also lipopolysaccharide-deficient <i>E. coli</i>, adhesion decreases substantially. …”

<i>S. boulardii</i> Fails to Hold Its Cell Wall Integrity against Nonpathogenic <i>E. coli</i>: Are Probiotic Yeasts Losing the Battle? by Satyajit Lenka (10290092)

“…When experiments are repeated with lipopolysaccharide-depleted <i>E. coli</i> and also lipopolysaccharide-deficient <i>E. coli</i>, adhesion decreases substantially. …”

<i>S. boulardii</i> Fails to Hold Its Cell Wall Integrity against Nonpathogenic <i>E. coli</i>: Are Probiotic Yeasts Losing the Battle? by Satyajit Lenka (10290092)

“…When experiments are repeated with lipopolysaccharide-depleted <i>E. coli</i> and also lipopolysaccharide-deficient <i>E. coli</i>, adhesion decreases substantially. …”