SSD - a free software for designing multimeric mono-, bi- and trivalent shRNAs by Gabriel José de Carli (8526942)

“…RT-qPCR analysis revealed that our molecule promoted a decrease in more than 50% of the target mRNA, in a dose-dependent manner, when compared to the control group. …”

What is the Impact of Outreach Services on Medication Adherence for COPD Patients? A Systematic Review by Elaine Marron (9753948)

“…CINAHL, Medline, Clinical Key and Cochrane library were all searched electronically along with grey literature for all eligible studies conducted on COPD patients in a non-acute hospital setting. Systematic review methodology was followed for data selection, extraction and risk of bias, validity testing and data analysis. …”

Resource consumption of multi-substance users in the emergency room: A neglected patient group by Laurence Klenk (7434560)

“…<div><p>Background</p><p>Multi-substance use is accompanied by increased morbidity and mortality and responsible for a large number of emergency department (ED) consultations. …”

hHSJ1a reduces levels of aggregated SOD1 in spinal cord. by Sergey S. Novoselov (452212)

“…(<b>B</b>) Representative Western blots of spinal cord lysates from indicated ages of male mice with anti-SOD1 (C4F6) resolved by SDS-PAGE in non-reducing conditions. Note the decrease in higher molecular weight (HMW) oligomers of SOD1 in DBLE spinal cords. …”

High-Resolution Recombination Patterns in a Region of Human Chromosome 21 Measured by Sperm Typing by Irene Tiemann-Boege (34093)

Cyclin G2 is a target molecule of Cn/NFATc2 in follicular keratinocytes. by Atsushi Fujimura (227683)

“…<p>(A) The microarray analysis identified 24 genes that showed down-regulated expression in PHK cells treated with either 11R-VIVIT or CsA; <i>ccng2</i> (cyclin G2) expression showed the greatest decrease after Cn/NFAT inhibition. …”

Modulation of HS α4β2 receptors with a low concentration of arecoline. by Roger L. Papke (685990)

“…After 8 minutes the responses to a control application of ACh was reduced approximately 50%. …”

Heterogeneous species increases over time due to continuous binding of Aβ42 to the neurites. by Chun-Chieh Chang (491709)

“…The green shaded sections represent the percentage of homogeneous Aβ40 in total Aβ40 species, and show the fraction of homogeneous Aβ40 to decrease over time. …”

Shifts caused by control and Grin2c siRNAs in stimulation threshold and maximum response rate. by Giovanni Hernandez (236411)

“…<p><b>A-B)</b> Histogram bars represent means +/- SEM; saline injection in the VTA does not produces a reliable change in M50 nor MAX <b>C)</b> Treatment with the control siRNA did not produce a significant change in the stimulation threshold (M50), but the treatment with the siRNA against the Grin2c subunit produces a significant increase. …”

A small proportion of Talin molecules transmit forces at developing muscle attachments in vivo by Sandra B. Lemke (6519788)

UNRAVELING PHYSIOLOGICAL TRAITS OF Jatropha curcas, A BIODIESEL PLANT, TO OVERCOME SALINITY CONDITIONS by YURI LIMA MELO (10481747)

“…Leaf growth, net photosynthesis and stomatal pore area were affected by 150 mM NaCl. Non-photochemical quenching of leaves was only changed by 150 mM NaCl after 24 h; the electron transport rate had a tendency to decrease in leaves under saline conditions. …”

The Effects of Extracorporeal Shock Wave Therapy in Patients with Coccydynia: A Randomized Controlled Trial by Shih-Feng Lin (824227)

“…Extracorporeal shock wave therapy (ESWT) was incorporated as non-invasive treatment of many musculoskeletal conditions. …”

On the development of gestural organization: A cross-sectional study of vowel-to-vowel anticipatory coarticulation by Elina Rubertus (5748872)

“…However, among children, a developmental decrease of vocalic coarticulation is only found for sequences including the alveolar stop /d/ which requires finer spatiotemporal coordination of the tongue’s subparts compared to labial and velar stops. …”

Supplementary Material for: Effects of wearing hearing aids on gait and cognition: A pilot study by figshare admin karger (2628495)

“…They subsequently underwent a baseline assessment prior to consistent HA use. …”

A beneficial allele goes to fixation faster in populations with high Cra expression noise. by Michael Schmutzer (6656663)

“…Both alleles occur in cells that have the same Cra expression noise, which is given by <i>η</i>² = 10 in (A), and <i>η</i>² = 0.01 in (B). Each plot show trajectories for 50 replicate population simulations. …”

Supplementary Material for: Epidemiology of Transthyretin Familial Amyloid Polyneuropathy in Portugal: A Nationwide Study by Inês M. (5678270)

“…<b><i>Results:</i></b> Over 2010–2016 period, mean incidence rates was 0.87/100,000 (95% CI 0.68–1.10) corresponding to 71 new patients yearly, that has decreased 31% in the last 7 years. …”

Factors associated with postoperative signs and symptoms in teeth with periapical lesion: a longitudinal study by Erlange Andrade Borges Silva (14224193)

“…Female gender (beta = 1.02; p < 0.01), mandibular teeth (beta = 25.50; p < 0.01), medium root canal amplitude (beta = 0.93; p = 0.03), and edema (beta = 1.88; p < 0.01) were associated with increased postoperative pain and tenderness, while the use of analgesics (beta = -1.82; p < 0.01) and time in days (beta = -0.23; p < 0.01) were associated with a decrease in these signs and symptoms. …”

Crystal structure and cytotoxic activities of a bis(pyrrolyl-imine) gold(III) complex by Daniel De Moraes Profirio (2885411)

“…Cytotoxic activity of [Au(pyren)]⁺ was active against three tumorigenic cell lines with IC₅₀ values of 35 μM. Interaction studies with CT-DNA by fluorescence and competition with ethidium bromide (EB) showed a quenching of the emission band of DNA with a Stern–Volmer quenching constant value of (3.0 ± 0.1) × 10⁴ M⁻¹ and a decrease in fluorescence quenching of EB-DNA system, respectively, confirming that DNA is a possible target for the complex via an intercalative binding, which was confirmed by DNA conformational changes observed with circular dichroism spectroscopy.…”

Sod2^-/- erythroid development is characterized by a maturational left shift. by Florent M. Martin (230825)

“…<p><b>A</b>. Sod2^-/- marrow (right) shows an increased fraction of immature basophilic erythroblasts (R4 gate: 1.9-fold increase) and decreased numbers of reticulocytes and mature RBC (R7 gate: 6-fold decrease), respectively, relative to Sod2^+/+ (left). …”

Development of a Mechanistic and Data-Driven Model for Multiphase Flow Leak Detection in Pipeline by Barooah, Abinash

“…The effect of different pressure constraints, pipe length, pipe diameter, two-phase fluid rheology, leak diameter, leak location, outlet liquid volume fraction, and flowing liquid hold-up on leak size, pressure, and flow rate is analyzed. Decreasing the liquid fraction in the outlet section of the leak leads to a slight increase (6% average) in the inlet mass flow rate and a significant decrease (50% average) in the outlet mass flow rate for fixed pressure constraints, resulting in an increased leak flow rate, pressure, and density. …”
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