Piroxicam and vehicle control do not impact canine UC cells <i>in vitro</i>. by Jordon M. Inkol (11237604)

“…<p>Representative IC50 curves for piroxicam treatment of AXA, Orig, and SH cells show no dose dependent decrease in cell viability up to 1mM (A). …”

dFmr1 regulates heart rate. by Stefanie Mares Novak (826953)

“…<b>(B)</b> Loss of dFmr1 (<i>dFmr1</i>^<i>3/50M</i>, N = 16) results in a statistically significant decrease in heart rate when compared to wild type (<i>w</i>^<i>1118</i>, N = 10). …”

Comparison of the theoretical impulsive SIR diffusion curve and the actual online on-demand streaming curve. by Peihua Fu (3138768)

“…<p>(a) The <i>J-shaped</i> solid curve indicates the general SIR diffusion process within the initial limited duration, while the piecewise broken curve indicates the step increment effect of impulsive stimulation at every update time <i>τ</i>_<i>k</i>. …”

Impact of KCNE1 expression on WT Kv7.1 and mutant R228C. by Liora Shamgar (44235)

“…Currents were evoked by a train of step depolarization to +30 mV. Similar results have been obtained in 5 other cells.…”

Proteins and mRNAs identified and affected by DA agonists in the hypothalamus of goldfish. by Jason T. Popesku (243373)

“…Negative values indicate a decrease relative to control. Absent values indicate either that no significant change was detected, or, in the case of the mRNAs, that the corresponding cDNA was not present on the array. mRNAs were annotated using Blast2GO's Blast Descriptor Annotator with default values except the Blast ExpectValue was changed from 1.0E-3 to 1.0E-5. …”

What is new in non-chromatographic flavonoid purification? by Leonardo de Oliveira Aguiar (14028342)

“…As the main advantage, these proceedings permitted good yields of bioactive flavonoids and biflavonoids, and they are improved when ultrasound, microwave, and mechanical extractors are used in the extraction step. Nevertheless, most of these techniques are not specific to a single molecule’s purification, except MIPs mainly used for analytical purposes. …”

Table_1_Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos.XLSX by Auke B. C. Otten (8965244)

“…Morphant embryos displayed abnormal development of the eye, brain, heart, and muscle, as well as a 50 ± 22% decrease in ATP production. Transcriptome analysis revealed a decrease in protein-encoding transcripts from the heavy strand of the mtDNA, and down-regulation of genes involved in haem production and the metabolism of metabolites, which appear to trigger increased rRNA and tRNA synthesis in the nucleoli. …”

Data_Sheet_1_Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos.PDF by Auke B. C. Otten (8965244)

“…Morphant embryos displayed abnormal development of the eye, brain, heart, and muscle, as well as a 50 ± 22% decrease in ATP production. Transcriptome analysis revealed a decrease in protein-encoding transcripts from the heavy strand of the mtDNA, and down-regulation of genes involved in haem production and the metabolism of metabolites, which appear to trigger increased rRNA and tRNA synthesis in the nucleoli. …”

Data_Sheet_3_Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos.PDF by Auke B. C. Otten (8965244)

“…Morphant embryos displayed abnormal development of the eye, brain, heart, and muscle, as well as a 50 ± 22% decrease in ATP production. Transcriptome analysis revealed a decrease in protein-encoding transcripts from the heavy strand of the mtDNA, and down-regulation of genes involved in haem production and the metabolism of metabolites, which appear to trigger increased rRNA and tRNA synthesis in the nucleoli. …”

Data_Sheet_2_Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos.pdf by Auke B. C. Otten (8965244)

“…Morphant embryos displayed abnormal development of the eye, brain, heart, and muscle, as well as a 50 ± 22% decrease in ATP production. Transcriptome analysis revealed a decrease in protein-encoding transcripts from the heavy strand of the mtDNA, and down-regulation of genes involved in haem production and the metabolism of metabolites, which appear to trigger increased rRNA and tRNA synthesis in the nucleoli. …”

Data_Sheet_4_Tfam Knockdown Results in Reduction of mtDNA Copy Number, OXPHOS Deficiency and Abnormalities in Zebrafish Embryos.PDF by Auke B. C. Otten (8965244)

“…Morphant embryos displayed abnormal development of the eye, brain, heart, and muscle, as well as a 50 ± 22% decrease in ATP production. Transcriptome analysis revealed a decrease in protein-encoding transcripts from the heavy strand of the mtDNA, and down-regulation of genes involved in haem production and the metabolism of metabolites, which appear to trigger increased rRNA and tRNA synthesis in the nucleoli. …”

Loss of intestinal epithelial Shh signaling deregulates intestinal crypt epithelial proliferation. by Jessica Gagné-Sansfaçon (571087)

“…Proliferation assays were performed by PCNA immunostaining (G and H, green labeling), with Evans blue serving as counterstain (red staining). Mutants displayed a decrease in cell proliferation as shown by a decrease in the number of PCNA-labeled proliferating cells (H) when compared to controls (G). …”

Test scores and ordering costs. by Jinghong Ma (1755838)

Displacement of site marker ligands bound to HSA in presence of increasing PS concentrations. by Shevin R. Feroz (468333)

“…Spectra marked as ‘a’, ‘b’, ‘c’ and ‘d’ refer to 10 µM BR, 10 µM HSA, 50 µM PS and PS–HSA (5∶1) complex, respectively. …”

Lovastatin inhibits VEGF induced activation of AKT and its downstream targets. by Tong T. Zhao (361937)

“…Phosphorylation level of AKT decreased with lovastatin treatment in a dose dependent manner. …”

Examples of CiVSP::cpEGFP constructs expression in HEK293 cells and voltage sensitivity. by Lauren Barnett (136642)

“…The probe exhibits a rapid decrease in fluorescence with a relatively low signal to noise ratio due to relatively weak basal fluorescence. …”

Other glycines substitutions that destabilize BH4-Bcl-2’s by Giovanni Monaco (452223)

“…Data points represent means ± SEM. * indicates a statistically significant difference from vehicle control.…”

Shh signaling is required for proper production of goblet cell secretory products and Paneth cell maturation. by Jessica Gagné-Sansfaçon (571087)

“…Immunostaining with an anti-lysozyme antibody showed a decrease in positively-labeled lysozyme cells (green staining) in mutant mice (E) compared to control littermates (D). …”

table_1_In Utero and Postnatal Propylthiouracil-Induced Mild Hypothyroidism Impairs Maternal Behavior in Mice.DOCX by Miski Aghnia Khairinisa (5213834)

“…As expected, locomotor and cognitive functions in these mice were disrupted in a PTU dose-dependent manner. On postpartum day 2, dams who had been exposed 50 ppm PTU during in utero and postnatal periods displayed a significantly longer time identifying the first pup and returning all three pups back to the nest, less time nursing, and decreased licking behavior. …”

table_2_In Utero and Postnatal Propylthiouracil-Induced Mild Hypothyroidism Impairs Maternal Behavior in Mice.DOCX by Miski Aghnia Khairinisa (5213834)

“…As expected, locomotor and cognitive functions in these mice were disrupted in a PTU dose-dependent manner. On postpartum day 2, dams who had been exposed 50 ppm PTU during in utero and postnatal periods displayed a significantly longer time identifying the first pup and returning all three pups back to the nest, less time nursing, and decreased licking behavior. …”