Image_3_A retrotransposon-derived DNA zip code internalizes myeloma cells through Clathrin-Rab5a-mediated endocytosis.tif by Pavan Kumar Puvvula (10495853)

“…Additionally, the loss of Rab5a decreased the Syntaxin-6 association with MMZC but not vice versa. …”

Image_2_A retrotransposon-derived DNA zip code internalizes myeloma cells through Clathrin-Rab5a-mediated endocytosis.tif by Pavan Kumar Puvvula (10495853)

“…Additionally, the loss of Rab5a decreased the Syntaxin-6 association with MMZC but not vice versa. …”

Gaussian growth curves modulate the rate of turnover of synaptic elements () in a neuron as a function of its [<i>Ca</i>²⁺]. by Ankur Sinha (10906249)

“…(<b>B</b>) <i>ψ</i> = <i>η</i> = 5.0, <i>ϵ</i> = 15.0, ν = 1.0, <i>ν</i> = 1.0, −<i>νω</i> = −1.0, <i>ν</i>(2 − <i>ω</i>) = 1.0 (see <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1008996#sec009" target="_blank">Methods</a>). …”

<i>E</i>. <i>faecium</i> protection in <i>hlh-26(ok1453);ref-1(ok288)</i> mutant. by Yu Sang (2551267)

Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold-Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa by Andrej Emanuel Cotman (5203904)

“…Starting from DNA gyrase inhibitor <b>1</b>, we identified compound <b>27</b>, featuring a 10-fold improved aqueous solubility, a 10-fold improved inhibition of topoisomerase IV from A. baumannii and P. aeruginosa, a 10-fold decreased inhibition of human topoisomerase IIα, and no cross-resistance to novobiocin. …”

A model for androgen-sensitized apoptosis of HPr-1AR. by Congcong Chen (796149)

“…However, the multi-target regulation of BCL2 family proteins by AR signaling may sufficiently stress the mitochondria towards a pro-apoptotic state (i.e., leaky outer membrane) and decrease the threshold for other apoptotic stimuli to further enhance permeabilization of the mitochondrial outer membrane above the necessary threshold for initiator and executioner caspase activation (caspase-9 and caspase-3, respectively) and apoptotic disassembly of the cells.…”

Testing for soil-transmitted helminth transmission elimination: Analysing the impact of the sensitivity of different diagnostic tools by Marleen Werkman (543388)

“…However, the impact of using qPCR on elimination thresholds is yet to be investigated. In this paper, we aim to quantify how the sensitivity of these two diagnostic tools affects the optimal prevalence threshold at which to declare the interruption of transmission with a defined level of confidence. …”

Table_2_A Functional Indel Polymorphism Within MIR155HG Is Associated With Sudden Cardiac Death Risk in a Chinese Population.XLSX by Qing Zhang (1802)

“…Collectively, we have successfully identified a SCD risk conferring polymorphism in the MIR155HG gene and a likely biological mechanism for the decreased risk of SCD associated with the deletion allele. …”

Table_1_A Functional Indel Polymorphism Within MIR155HG Is Associated With Sudden Cardiac Death Risk in a Chinese Population.DOCX by Qing Zhang (1802)

“…Collectively, we have successfully identified a SCD risk conferring polymorphism in the MIR155HG gene and a likely biological mechanism for the decreased risk of SCD associated with the deletion allele. …”

Table_3_A Functional Indel Polymorphism Within MIR155HG Is Associated With Sudden Cardiac Death Risk in a Chinese Population.XLSX by Qing Zhang (1802)

“…Collectively, we have successfully identified a SCD risk conferring polymorphism in the MIR155HG gene and a likely biological mechanism for the decreased risk of SCD associated with the deletion allele. …”

MiR-148a Functions as a Tumor Suppressor by Targeting CCK-BR via Inactivating STAT3 and Akt in Human Gastric Cancer by Beiqin Yu (425867)

“…Subsequently, we identified cholecystokinin B receptor (CCK-BR) as a direct target of miR-148a using western blot and luciferase activity assay. …”

The workflow of this study. by Juan Hu (676613)

“…Serum miR-106a-5p derived from liver fibrosis was decreased compared with healthy individuals. …”

Univariate linear regression analysis of scales. by Xiangyu Wang (341093)

“…Moreover, Life Sciences & Medicine students demonstrated a greater tendency toward negative self-perception, low psychological well-being level, and decreased creative self-efficacy, compared to peers in other disciplines.…”

The MELD-Plus: A generalizable prediction risk score in cirrhosis by Uri Kartoun (4535194)

“…We then used a regularized logistic regression to select the most informative variables and created a risk score that comprises the selected variables. …”

Formation and Dynamics of Waves in a Cortical Model of Cholinergic Modulation by James P. Roach (785792)

“…A further decrease in ACh leads to a high degree of synchrony within traveling waves. …”

Mood training resilience. by Vasileios Mantas (16949352)

Image1_A causal association between lipid-lowering medications and rotator cuff syndrome: a drug-targeted mendelian randomization study.TIF by Meng-meng Liu (18241785)

“…For the drug targets that showed significant results, further analysis was done using Summary-data-based Mendelian Randomization (SMR) and colocalization techniques. We performed a mediation analysis to identify potential mediators between HMG-CoA reductase (HMGCR) and RCS.…”

Table1_A causal association between lipid-lowering medications and rotator cuff syndrome: a drug-targeted mendelian randomization study.DOCX by Meng-meng Liu (18241785)

“…For the drug targets that showed significant results, further analysis was done using Summary-data-based Mendelian Randomization (SMR) and colocalization techniques. We performed a mediation analysis to identify potential mediators between HMG-CoA reductase (HMGCR) and RCS.…”

Table2_A causal association between lipid-lowering medications and rotator cuff syndrome: a drug-targeted mendelian randomization study.XLSX by Meng-meng Liu (18241785)

“…For the drug targets that showed significant results, further analysis was done using Summary-data-based Mendelian Randomization (SMR) and colocalization techniques. We performed a mediation analysis to identify potential mediators between HMG-CoA reductase (HMGCR) and RCS.…”

Image2_A causal association between lipid-lowering medications and rotator cuff syndrome: a drug-targeted mendelian randomization study.TIF by Meng-meng Liu (18241785)

“…For the drug targets that showed significant results, further analysis was done using Summary-data-based Mendelian Randomization (SMR) and colocalization techniques. We performed a mediation analysis to identify potential mediators between HMG-CoA reductase (HMGCR) and RCS.…”