Synthesis and Characterization of the First Azastibatranes and Azabismatranes by Pavel L. Shutov (2967693)

“…The structural data obtained from geometry optimizations on <b>6</b> and <b>8</b> reproduce experimental trends, i.e., a decrease in the E−N_dat distance from Sb to Bi. …”

Synthesis and Characterization of the First Azastibatranes and Azabismatranes by Pavel L. Shutov (2967693)

“…The structural data obtained from geometry optimizations on <b>6</b> and <b>8</b> reproduce experimental trends, i.e., a decrease in the E−N_dat distance from Sb to Bi. …”

Synthesis and Characterization of the First Azastibatranes and Azabismatranes by Pavel L. Shutov (2967693)

“…The structural data obtained from geometry optimizations on <b>6</b> and <b>8</b> reproduce experimental trends, i.e., a decrease in the E−N_dat distance from Sb to Bi. …”

Synthesis and Characterization of the First Azastibatranes and Azabismatranes by Pavel L. Shutov (2967693)

“…The structural data obtained from geometry optimizations on <b>6</b> and <b>8</b> reproduce experimental trends, i.e., a decrease in the E−N_dat distance from Sb to Bi. …”

Synthesis and Characterization of the First Azastibatranes and Azabismatranes by Pavel L. Shutov (2967693)

“…The structural data obtained from geometry optimizations on <b>6</b> and <b>8</b> reproduce experimental trends, i.e., a decrease in the E−N_dat distance from Sb to Bi. …”

Synthesis and Characterization of the First Azastibatranes and Azabismatranes by Pavel L. Shutov (2967693)

“…The structural data obtained from geometry optimizations on <b>6</b> and <b>8</b> reproduce experimental trends, i.e., a decrease in the E−N_dat distance from Sb to Bi. …”

RTA 408, A Novel Synthetic Triterpenoid with Broad Anticancer and Anti-Inflammatory Activity by Brandon L. Probst (727964)

“…Here, we characterized the in vitro antioxidant, anti-inflammatory, and anticancer activities of RTA 408, a novel AIM that is currently being evaluated in patients with advanced malignancies. …”

FLIM FRET efficiency of: (A) αA-crystallin (B) WT αB-crystallin, their deamidated and domain mutants. by Ekta Tiwary (836674)

Data file. by Maryam Khalaji (21743611)

“…The results showed that mental fatigue significantly decreased QE duration (Mean difference = −138.75 ms, p = .0009) and fixation duration (Mean difference = 67.50 ms, p = .001), indicating a detrimental effect on sustained attention. …”

<i>Jagged 1</i> and <i>Nur77</i> expression shows an inverse relationship. by Sudeep Kumar (205149)

Structure-Based Design, Synthesis, and Biological Evaluation of New Triazolo[1,5‑<i>a</i>]Pyrimidine Derivatives as Highly Potent and Orally Active ABCB1 Modulators by Shuai Wang (109515)

“…In this work, we reported the structure-based design of triazolo­[1,5-<i>a</i>]­pyrimidines as new ABCB1 modulators, of which <b>WS-691</b> significantly increased sensitization of ABCB1-overexpressed SW620/Ad300 cells to paclitaxel (PTX) (IC₅₀ = 22.02 nM). …”

Structure-Based Design, Synthesis, and Biological Evaluation of New Triazolo[1,5‑<i>a</i>]Pyrimidine Derivatives as Highly Potent and Orally Active ABCB1 Modulators by Shuai Wang (109515)

“…In this work, we reported the structure-based design of triazolo­[1,5-<i>a</i>]­pyrimidines as new ABCB1 modulators, of which <b>WS-691</b> significantly increased sensitization of ABCB1-overexpressed SW620/Ad300 cells to paclitaxel (PTX) (IC₅₀ = 22.02 nM). …”

Structure-Based Design, Synthesis, and Biological Evaluation of New Triazolo[1,5‑<i>a</i>]Pyrimidine Derivatives as Highly Potent and Orally Active ABCB1 Modulators by Shuai Wang (109515)

“…In this work, we reported the structure-based design of triazolo­[1,5-<i>a</i>]­pyrimidines as new ABCB1 modulators, of which <b>WS-691</b> significantly increased sensitization of ABCB1-overexpressed SW620/Ad300 cells to paclitaxel (PTX) (IC₅₀ = 22.02 nM). …”

The effects of cytokine priming on the virus replication in moDCs. by Veera Arilahti (560851)

“…<p>Monocyte-derived human DCs from four different blood donors were primed with different doses of IFN-α (1, 10 or 100 IU/ml), IFN-β (1, 10 or 100 IU/ml), TNF-α (0.5, 5 or 50 ng/ml), or IL-1β (1, 10 or 100 ng/ml) for 24 h followed by infection with H3N2 or H7N9 viruses for 24 hours. …”

N⁶-methyladenosine-dependent primary microRNA-126 processing activated PI3K-AKT-mTOR pathway drove the development of pulmonary fibrosis induced by nanoscale carbon blac... by Bin Han (45760)

“…We found that both of m⁶A modifications of pri-miRNA-126 and its binding with DGCR8 were decreased after CB treatment, which resulted in the reduction of mature miRNA-126 accompanied by accumulation of unprocessed pri-miRNA-126. …”

PP2B inhibitors increase phosphorylated Ser295 of PSD-95 in cultured mouse cortical neurons. by Takahiko Chimura (729098)

CI-regulated utilization of alternative carbon sources is vital for <i>C</i>. <i>albicans</i> commensalism in GI tract. by Xinhua Huang (1905940)

On a steepening environmental gradient, a sharp and stable range margin forms near the expansion threshold. by Jitka Polechová (5400749)

“…(<b>b</b>) As the environmental gradient steepens, the frequency of limited adaptation within the metapopulation increases (black and grey), and hence neutral variation decreases (blue). The black line gives the proportion of demes with limited adaptation after 50,000 generations, when the range margin appears stable; grey gives the proportion after 40,000 generations (depicted is an average over a sliding window of 15 demes). …”

The comparison of CD4⁺ count, CD4/CD8 ratio, and HIV RNA load levels. by Qinzhi Zhang (19871125)

DataSheet_1_A20 Establishes Negative Feedback With TRAF6/NF-κB and Attenuates Early Brain Injury After Experimental Subarachnoid Hemorrhage.zip by Hong-Ji Deng (11182902)

“…<p>Nuclear factor (NF)-κB–ty -50mediated neuroinflammation plays a crucial role in early brain injury (EBI) after subarachnoid hemorrhage (SAH). …”