Image 2_Evaluation of the cytotoxicity and antibacterial activity of a synthetic tunicamycin derivative against Mycobacterium avium complex.jpeg by Maria A. Colombatti Olivieri (21362615)

“…Also, low-dose TunR2 treatment of infected macrophages did not significantly decrease Map survival after 48 h of infection. These results suggest that TunR2 is not a good candidate to treat Map infections.…”

Image 1_Evaluation of the cytotoxicity and antibacterial activity of a synthetic tunicamycin derivative against Mycobacterium avium complex.jpeg by Maria A. Colombatti Olivieri (21362615)

“…Also, low-dose TunR2 treatment of infected macrophages did not significantly decrease Map survival after 48 h of infection. These results suggest that TunR2 is not a good candidate to treat Map infections.…”

Table 2_Evaluation of the cytotoxicity and antibacterial activity of a synthetic tunicamycin derivative against Mycobacterium avium complex.docx by Maria A. Colombatti Olivieri (21362615)

“…Also, low-dose TunR2 treatment of infected macrophages did not significantly decrease Map survival after 48 h of infection. These results suggest that TunR2 is not a good candidate to treat Map infections.…”

Table 1_Evaluation of the cytotoxicity and antibacterial activity of a synthetic tunicamycin derivative against Mycobacterium avium complex.docx by Maria A. Colombatti Olivieri (21362615)

“…Also, low-dose TunR2 treatment of infected macrophages did not significantly decrease Map survival after 48 h of infection. These results suggest that TunR2 is not a good candidate to treat Map infections.…”

Distribution of SARS-CoV-2 RNA+ cells in lungs of hamsters after intranasal inoculation with B.1 (614G), B.1.427 and B.1.429 by in-situ hybridization (ISH). by Timothy Carroll (3762841)

Gender and T cell responses. by Annemarie Namuniina (16496648)

“…The rates of cross-reactive T-cell populations in this exploratory Ugandan population appears higher than previous estimates from resource-rich countries like the United States (20–50% reactivity). It is unclear what role, if any, this cross-reactivity played in decreasing COVID-19 related mortality in Uganda and other African countries, but does suggest that a better understanding of global pre-existing immunological cross-reactivity could be an informative data of epidemiological intelligence moving forward.…”

Clade III N-AChR show similar agonist affinities. by Jennifer D. Noonan (14117157)

“…<p>Concentration- response curves were measured to determine if declining maximal response is due to decreasing ligand affinity. Concentration-response curves for clade III N-AChRs for (A) acetylcholine and (B) nicotine. …”

Rates of hospital admission stratified by gender. by Abdallah Y. Naser (4856113)

“…Rates of same-day hospital admission decreased by 13.3% [from 50.55 (95%CI 49.54–51.57) in 1998 to 43.81 (95%CI 43.00–44.63) in 2019 per 100,000 persons]. …”

Inhibition of AurA or HDAC6 by inhibitors preserves ciliary structure during porcine CoVs infection. by Tenghan Zhuang (22238809)

“…Tubacin treatment increased AcTub levels, while PHA-680632 (PHA) treatment decreased pAurA levels, indicating successful inhibition of AurA and HDAC6. …”

Image_1_Molecular mechanisms regulating natural menopause in the female ovary: a study based on transcriptomic data.jpeg by Quan Liu (486219)

“…Increased contents of terminally differentiated HMGB1+ Granulosa and GSTA1+ Granulosa were observed in the ovaries of individuals aged 50-69. Signaling pathway activity analysis indicated a gradual decrease in TGFb and MAPK pathway activity with menopause progression, while p53 pathway activity increased. …”

<b>Uncovering the role of the yeast lysine acetyltransferase NuA4 in the regulation of nuclear shape and lipid metabolism</b> by Sarah Laframboise (18338787)

“…Disruption of the NuA4 complex results in 70% of cells displaying nuclear deformations and nearly 50% of cells exhibiting vacuolar fragmentation. …”

Celecoxib activates SIRT1 in a biochemical, <i>in silico</i> and <i>in vitro</i> cell-based assay. by Madhavi Annamanedi (580922)

“…Right - Model showing the interactions of Celecoxib with SIRT1 protein. C. A representative Western blot showing a dose-dependent decrease of Ac-H3K9 levels in presence of celecoxib. * p-value<0.01 compared to Control. …”

The formation of a negative image mediated by anti-Hebbian burst time dependent plasticity reduces signal but not noise correlations. by Benjamin Simmonds (682287)

“…<p><b>A</b>) One cycle of the 4 Hz sinusoidal stimulus (top, red trace) and synaptic weights (bottom, blue traces) as a function of time for (black traces from top to bottom), t = 0, t = 0.5 sec, t = 1 sec, t = 1.5 sec, t = 2 sec, t = 2.5 sec, t = 3 sec, t = 3.5 sec, t = 4 sec, t = 4.5 sec, t = 5 sec, t = 5.5 sec. …”

Data_Sheet_1_Case Report: A Novel Mutation in NFKB1 Associated With Pyoderma Gangrenosum.PDF by Ran Fang (533948)

“…The functional analysis showed that the variant caused reduced phosphorylation of p105 and resulted in the decreased processing of p105 to p50. We conclude that the patient's symptoms were caused by dysregulation of the NF-κB signaling pathway.…”

Anti-PCSK9 vaccine approach is boostable, and induced functional antibodies even after a single yearly re-boost. by Gergana Galabova (669355)

“…Note the slight loss of effect on TC levels over time (for example, by W42 and W50), and the induction of a significantly beneficial decrease following the re-boost immunization at W54. …”

The levels of ParB_Bb and ParA_Bb vary differently during the cell cycle. by Jovana Kaljević (17020971)

“…Graphical illustration of the cell cycle stages corresponding to the indicated time points. Arrowhead points to ParB_Bb (detected only during GP). …”

Data from: Large subsurface carbon stocks in a long-term no-tillage site are vulnerable to potential mineralization by Qiuping Peng (20147290)

“…Soil cores were sampled to 153 cm depth at 25 locations representing 5 distinct soil series, a range in landscape positions, and a range in profile organic carbon contents. …”

Are Environmental Levels of Nonsteroidal Anti-Inflammatory Drugs a Reason for Concern? Chronic Life-Cycle Effects of Naproxen in Zebrafish by Susana Barros (586042)

“…The nonsteroidal anti-inflammatory drug naproxen (NPX) is among the most consumed pharmaceuticals worldwide, being detected in surface waters within the ng to μg/L range. Considering the limited chronic ecotoxicity data available for NPX in aquatic ecosystems, the present study aimed at evaluating its impact in the model organism Danio rerio, following a full life-cycle exposure to environmentally relevant concentrations (0.1 to 5.0 μg/L). …”

Image_1_Case Report: Mature Plasmacytoid Dendritic Cell Proliferation Associated With a Lymphoid Neoplasm.tiff by Fei Fei (794241)

“…Analysis of the pDC frequency in a separate cohort of T-ALL and control patients demonstrated that bone marrow pDCs are often decreased in patients with T-ALL compared to controls. …”

Image_3_Case Report: Mature Plasmacytoid Dendritic Cell Proliferation Associated With a Lymphoid Neoplasm.tiff by Fei Fei (794241)

“…Analysis of the pDC frequency in a separate cohort of T-ALL and control patients demonstrated that bone marrow pDCs are often decreased in patients with T-ALL compared to controls. …”