Discovery of IHMT-MST1-58 as a Novel, Potent, and Selective MST1 Inhibitor for the Treatment of Type 1/2 Diabetes by Yun Wu (150224)

Subjects:

Cell-penetrating 15mer peptides decrease the proliferation and viability of cancer cells. by Pavan Kumar Puvvula (10495853)

Example of AOI/POI definitions and selected mixture components. by Nak Won Rim (10776698)

Cnot4 heterozygosity confers resistance to high fat diet-induced obesity. by Tomokazu Yamaguchi (8284989)

ATG13 is a substrate of CDK1/cyclin B in mitosis. by Zhiyuan Li (205620)

“…(E) shows representative western blot analysis of the ATG13 immunoprecipitates as substrate, and (F) shows the representative western blot analysis of the ULK1-WT coimmunoprecipitates as substrate. AMPK, AMP-activated protein kinase; ATG, autophagy-related; CDK, cyclin-dependent kinase; FIP200, FAK family-interacting protein of 200; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; GFP, green fluorescent protein; IP, immunoprecipitation; mULK1, mouse ULK1; ULK1, unc-51-like autophagy activating kinase 1; WT, wild type.…”

Copper contamination impairs herbivore initiation of seaweed inducible defenses and decreases their effectiveness by Alexandria Warneke (728820)

Dysregulation of Myosin Complex and Striated Muscle Contraction Pathway in the Brains of ALS–SOD1 Model Mice by Benhong Xu (4924132)

“…In the Striated Muscle Contraction Pathway, most of the identified proteins were decreased in the SOD1^G93A mice compared with the WT mice. …”

Knockout of CD146 in the nervous system resulted in decreased locomotor activity in mice. by Tao Tu (456663)

Regions of significantly decreased ACM of SP-MS relative to RR-MS patients. by Mark Lyksborg (583318)

Decreased proliferation after overexpression of T-STAR in five breast cancer cell lines. by Sandra Sernbo (438551)

“…C) A decrease in proliferation could be detected at 48 h after overexpressing T-STAR using thymidine incorporation and D) after 48 h (PMC42, L56Br-C1 and T47D) or 72 h (JIMT-1 and MDA-MB-231) upon assessment of enzymatic activity (WST-1 assay). …”

Effects of CR-induced Schwann cells autophagy on remyelination. by Roberto Coccurello (225087)

“…MPZ is overexpressed 7 days after CCI in WT ST vs Naïve (°°P<0,001) and decreased in CR vs ST (*P<0,05); in Ambra1 mice MPZ is down-expressed (^<b>§§</b>P<0,001 vs WT ST) and ameliorated by CR (*P<0,05 CR vs A+/- ST). …”

RNAP II CTD phosphoserine-2 levels decreased with increasing amounts of DRB. by Mark Ou (474248)

Table S2 from Fin whale singing decreases with increased swimming speed by Christopher W. Clark (354702)

Table S2 from Fin whale singing decreases with increased swimming speed. by Christopher W. Clark (354702)

Frequency of septicemic plague in the absence of primary pneumonia increases with decreasing dosing volume. by Rachel M. Olson (6729983)

The transmission decreases as the distance or PM_2.5 index increases. by Chenbin Liu (1405879)

Naloxone decreases the number of apoptotic cells induced by morphine but does not affect their profile. by Dafna Willner (605895)

Decreased Sho levels in different animal models infected with diverse prion strains. by Joel C. Watts (195735)

“…<p>(<b>A</b>) Western blot analysis of brain homogenates prepared from wt FVB mice (expressing the PrP-A allotype) infected with RML, 22L, Me7, and 301V prions, and B6.I mice (expressing the PrP-B allotype) infected with 87V and 301V prions. …”

Decreased lymphoproliferative responses in mice treated with <i>Ac</i>-TMP-1. by Carmen Cuéllar (372690)

Decreased repair temperature exhibits differential effects on repair of prompt DSB and HSCS. by Andris Abramenkovs (6162875)