Concordant and discordant read coverage reveal extensive similarity between the tumor and control. by Cem Sievers (584576)

“…In contrast, heterozygous events contain both a wildtype allele and an acquired SV, and are therefore characterized by a decrease within the concordant coverage to 50% (III). …”

Electrophysiological response of Be2C cells in response to stimulation with morphine. by Marino Convertino (247429)

“…<b>B)</b> Morphine stimulation of Be2C cells transfected with the 6TM-mOR leads to a decrease in an outward current with a reversal potential near -80 mV, suggesting that K⁺ conductance is reduced. …”

CPF alone prevented ability of adipogenic cocktail (DMI) towards differentiation of C₃H₁₀T½ cells to adipocytic lineage. by Harkirat Singh Sandhu (3836335)

“…Increasing concentrations of CPF (0.01, 0.1, 1, 10, 25, 50 and 100 μM) caused a gradual decrease in lipid vesicle accumulation of DMI-treated cells (e-k). …”

Double immunohistostaining of alpha-synuclein and TH. by Nian Xiong (218611)

“…The last graph of the three rows was obtained by the overlapping the first three graphs (Scale bars = 50 µm). Compared with the contralateral side of the ST models (A-D), a dose-dependent increase in alpha-synuclein expression in the lesioned brain and a decrease in the number of TH-positive neurons are shown in E–H (3-µg group) and I–L (12-µg group). …”

The proportion of homomeric GluR1 AMPA receptors in the post-synaptic sites is not altered following LTP induction. by Agnès Villers (316323)

“…<p>In these experiments, slices were treated with a 1-hour perfusion of NASPM (50 µM), an inhibitor of GluR2-lacking AMPA receptors. …”

Efflux of ethidium bromide. by Helen E. McNeil (8190873)

“…Data presented is the time taken for the fluorescence to decrease by 25% +/- SE. (Data for 10% and 50% drop can be seen in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1008101#ppat.1008101.s011" target="_blank">S1 Table</a>). …”

Tumor microenvironment facilitates the emergence of high levels of drug resistance. by Feng Fu (218124)

“…In the absence of drugs, both proliferation and turnover rates of cancer cells decrease with <i>x</i> [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1004142#pcbi.1004142.ref022" target="_blank">22</a>]: birth rate <i>β</i>(<i>x</i>) = <i>b</i>₀exp(−<i>x</i>/<i>τ</i>_<i>g</i>) and death rate <i>α</i>(<i>x</i>) = <i>d</i>₀exp(−<i>x</i>/<i>τ</i>_<i>g</i>), where the parameter <i>τ</i>_<i>g</i> is the characteristic length scale of spatial decay in proliferation and turnover rates. …”

FGF2 regulates otic gene expression through the MAP kinase pathway. by Lu Yang (30847)

“…Trigeminal level ectoderm was cultured with 50 ng/ml FGF2 in the presence or absence of 20 µM U0126. …”

Gel filtration and EMSA analysis of the WT N protein purified from HEK293S GNTI- cells. by Amanda Jack (11547638)

“…<b>(F)</b> EMSA using no RNA, 10 nM 0–5 kb viral RNA, and 50 ng/μL polyC RNA and decreasing concentration of N protein. …”

Supplementary Material for: Impact of Simulated Hyperventilation and Periodic Breathing on Sympatho-Vagal Balance and Hemodynamics in Patients with and without Heart Failure by Spiesshoefer J. (7139138)

“…<b><i>Results:</i></b> In healthy subjects, voluntary hyperventilation led to a 50% decrease in the mean BRS slope and a 29% increase in CI compared to baseline values (<i>p</i> < 0.01 and <i>p</i> < 0.05). …”

DataSheet_1_Decadal variability of oxygen uptake, export, and storage in the Labrador Sea from observations and CMIP6 models.pdf by Jannes Koelling (6811805)

“…In the CMIP6-OMIP1 multi-model mean, oxygen uptake has its maximum in 1980–1992, followed by a decrease in 1994–2006. There is a concurrent decrease in export, but oxygen storage also changes between the two periods, with oxygen accumulated in the first period and drained out in the second. …”

Data_Sheet_1_Light Limitation and Depth-Variable Sedimentation Drives Vertical Reef Compression on Turbid Coral Reefs.pdf by Kyle M. Morgan (6567200)

“…Assuming no further declines in water quality, future sea level rise could decrease the depth distribution of these turbid reefs by a further 8–12%. …”

Nogo-66 activated mTOR-STAT3 signaling in NPCs astroglial differentiation. by Bin Wang (30851)

“…<p>(A) Gel imagine of RT-PCR for NgR mRNA expression in NPCs. …”

Data_Sheet_1_A Pilot Study of a Parent Emotion Socialization Intervention: Impact on Parent Behavior, Child Self-Regulation, and Adjustment.PDF by Evalill Bølstad (11568514)

“…Further research with a larger sample will be the next step to determine if these pilot findings are seen in an adequately powered study.…”

IL-17 can be protective or deleterious in murine pneumococcal pneumonia by Neil D. Ritchie (694167)

“…Nasal colonization is an essential step prior to infection. The cytokine IL-17 protects against such colonization and vaccines that enhance IL-17 responses to pneumococcal colonization are being developed. …”

Barriers and facilitators to employment in borderline personality disorder: A qualitative study among patients, mental health practitioners and insurance physicians by Trees T. Juurlink (7027232)

“…As a next step, supported employment strategies that follow patient preferences and integrate employment and mental health services, should be studied in the context of BPD.…”

Table_1_Shark Antibody Variable Domains Rigidify Upon Affinity Maturation—Understanding the Potential of Shark Immunoglobulins as Therapeutics.docx by Monica L. Fernández-Quintero (6178163)

“…Furthermore, we were able to kinetically and thermodynamically describe the binding process and did not only identify a two-step binding mechanism, but we also found a strong population shift upon affinity maturation toward the native binding pose.…”

Prevalence of Burnout among Medical Residents of a University Hospital by Marina Macedo Kuenzer Bond (5766356)

“…The medical professional’s training period includes medical residency, a step in which stressors factors can be magnified. …”

Table_1_The impact of China's zero markup drug policy on drug costs for managing Parkinson's disease and its complications: an interrupted time series analysis.docx by Ruilin Wang (1452577)

“…An interrupted time series analysis was conducted to evaluate the immediate change following the intervention (step change, β₁) and the change in slope, comparing post-intervention with the pre-intervention period (trend change, β₂). …”

Cell death and JNK activation in SH-SY5Y cells stimulated with H₂O₂ overnight or for 3 h. by Marco Feligioni (287395)

“…<b>D</b>) Cell viability assay was performed employing MTT colorimetric method. A concentration dependent decrease in cell viability is observed following 3 h stimulation with H₂O₂ (50 mM: ∼30%; 75 mM: ∼50%). …”