Prolonged Activation of the Htr2b Serotonin Receptor Impairs Glucose Stimulated Insulin Secretion and Mitochondrial Function in MIN6 Cells by Luis Rodrigo Cataldo (3701206)

“…<div><p>Aims</p><p>Pancreatic β-cells synthesize and release serotonin (5 hydroxytryptamine, 5HT); however, the role of 5HT receptors on glucose stimulated insulin secretion (GSIS) and the mechanisms mediating this function is not fully understood. …”

5.HT_1A binding difference between known cause of death (KCOD) controls and SIDS. by Hannah C. Kinney (10280975)

“…When SIDS is compared to all KCOD controls, the HG, NTS, and MAO show a significant mean difference in 5-HT_1A receptor binding. Data include the combined South Africa and Northern Plains cohorts.…”

Adenylate cyclase activation does not cause translocation of PKC Apl II in response to 5HT in Sf9 cells. by Carole A. Farah (336422)

“…<p><b>A)</b> Sf9 cells were cotransfected with mRFP-PKC Apl II along with either eGFP-5HT_4Apl (n = 17), eGFP-5HT_7Apl (n = 15) or eGFP-5HT_2Apl (n = 9). …”

HoxA9-ER directly represses <i>Cebpa</i> gene expression in myeloid cells. by Lei Peng (260321)

HT1080 human sarcoma xenograft growth in CD-1 athymic mice and body weight comparison under therapy with intravenous (i.v.) tTF-NGR, tumor radiotherapy, and a combination of both t... by Caroline Brand (3448523)

Anti-transforming growth factor beta (TGFβ) Ab decreased aristolochic acid (AA)-induced reticulum endoplasmic (ER) and mitochondrial (MT) stress protein expression in kidney tissue... by Agnieszka A. Pozdzik (3159222)

“…(<b>b-d</b>) Cell lysates from HUVEC and HK-2 incubated for 6 and 24 h with 50 ng/ml of AA and anti-TGFβ Ab or control Ab were immunobloted for ATPB, alpha smooth muscle actin (α-SMA), E-cadherin, ATPB, SDHA, p-PERK, vimentin, p-Smad2, p-Smad3, and tubulin proteins expression. …”

Cell-cell adhesion and expression profile of osteoblastic markers of 5-HT_2BR-/- osteoblasts. by Yasmine Chabbi-Achengli (459899)

“…Runx2, osteocalcin expression levels were not modified by the absence of 5-HT_2BR, whereas cyclin D1, alkaline phosphatase and osteopontin expression levels were decreased. …”

HC11 cells increase Pthlh gene expression and activity via cAMP with increases in intracellular 5HT. by Celeste M. Sheftel (9557588)

“…<p><b>A-C.</b> 5HTP significantly increases intracellular 5HT at 12- and 72 hours post treatment compared to baseline and at 12 hours compared to lactogenic control <b>(B).…”

Predictive values of IC₅₀ in mM (FFAs) for vanadium compounds and <i>in vivo</i> observations IC₅₀ in mM (FFAs) and decreasing blood glucose level. by Elena V. Fedorova (603922)

Top 50 genes whose expression is most decreased in PN11 <i>Klf5</i>CN compared with the WT corneas. by Doreswamy Kenchegowda (135193)

Top 50 genes whose expression is most decreased in PN56 <i>Klf5</i>CN compared with the WT corneas. by Doreswamy Kenchegowda (135193)

Susceptibility of half knockout strains to CYP51 inhibitors (EC50, μM): compounds with decreased activity on HKO + CYP strains. by Laura-Isobel McCall (222498)

Table_1_Gender-Specific Effect of 5-HT and 5-HIAA on Threshold Level of Behavioral Symptoms and Sex-Bias in Prevalence of Autism Spectrum Disorder.DOCX by Barnali Chakraborti (3410288)

“…Age did not influence the neurochemical parameters, but imitation, listening responses and nonverbal communication scores decreased with age. Conversely in female probands, plasma 5-HIAA level significantly attenuated with age, when platelet 5-HT content remained unchanged. …”

KDM6A mRNA expression is decreased in PTFE mice. by Simon Lebek (9756148)

A Model of Post-Infection Fatigue Is Associated with Increased TNF and 5-HT_2A Receptor Expression in Mice by Yvonne Couch (766341)

“…<div><p>It is well documented that serotonin (5-HT) plays an important role in psychiatric illness. …”

Data_Sheet_1_Leptin Increases Expression of 5-HT2B Receptors in Astrocytes Thus Enhancing Action of Fluoxetine on the Depressive Behavior Induced by Sleep Deprivation.docx by Xiaowei Li (620087)

“…In this study, we discovered: (i) that activation of NLRP3 inflammasome was involved in the depressive-like behaviors induced by SD; (ii) decrease in BDNF following SD required the activation of NLRP3 inflammasomes; (iii) leptin augmented the anti-depressive action of fluoxetine through an increase in expression of astrocytic 5-HT_2B receptors. …”

Effect of low doses of clothianidin on oriented responses of <i>A. ipsilon</i> males towards a 20-ng sex pheromone blend. by Kaouther K. Rabhi (675942)

“…<p>The percentage of responses of clothianidin-treated males divided by that of DMSO-treated males is represented. The 0.25-ng dose induced a significant decrease in oriented responses whereas the 10-ng dose induced a significant increase in sex pheromone oriented responses. …”

NTF effect on neuronal morphologies Effect of 50 ng/ml BDNF, 100 ng/ml CNTF and the combination of both NTFs (B/C) compared to negative control (NC) on neuronal morphology in terms... by Jana Schwieger (782065)

Nearly 1000 Protein Identifications from 50 ng of <i>Xenopus laevis</i> Zygote Homogenate Using Online Sample Preparation on a Strong Cation Exchange Monolith Based Microreactor Co... by Zhenbin Zhang (1444888)

“…This combination of basic elution and acidic background electrolytes results in both sample stacking and formation of a dynamic pH junction. 369 protein groups and 1274 peptides were identified from 50 ng of <i>Xenopus laevis</i> zygote homogenate, which is comparable with an offline sample preparation method, but the time required for sample preparation was decreased from over 24 h to less than 40 min. …”

Five compounds significantly decrease MAPK1 phosphorylation in K562 cells. by Pamela Y. Ting (713174)