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17961
The E1B19K protein plays an essential role in adenovirus-mediated autophagy.
Published 2013“…Deletion of E1BK jeopardizes adenovirus-associated autophagy, as assessed by a significant decrease in the LC3 membrane localization. …”
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17962
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17963
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17964
Bcl-xL siRNA effectively knocks down Bcl-xL mRNA and protein and induces platelet apoptosis.
Published 2015“…<p>Leukocyte-depleted apheresis platelets (LDPs) were transfected with siBcl-xL or negative control siRNA (siNC) at a final concentration of 50 nM. LDPs without transfection were used as blank controls (control). …”
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17965
Parasympathetic blockade by methylatropine prevents bradycardia during seizure and in the immediate post-ictal period.
Published 2019“…<b>D:</b> The change in heart rate for individual mice in the absence of methylatropine is shown. Note the rapid decrease in heart rate in the clonic period with a further decrease by the end of the tonic period. …”
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17966
<i>In vitro</i> and <i>in vivo</i> properties of aminotriazines used in this study.
Published 2015“…Analgesic efficacy was determined by a statistically significant (p < 0.05) decrease in formalin-induced flinching for which the same dose did not produce a reduction in movement in the open field assay that obviated the formalin result. …”
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17967
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17968
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17969
Signal transduction.
Published 2013“…Data from a subset of the IFN-induced genes is shown. Fold increase (decrease) is normalized to results for mock-infected cells.…”
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17970
Cryoinjury transiently impairs ventricular pumping efficiency.
Published 2014“…<b>(B)</b> Cryoinjured animals show a temporal decrease in the RFVS of 50%, which is gradually recovered around 60 dpi (*** p<0.001; ** p<0.01; * p<0.05; one-way ANOVA followed by Tukey's honest significant difference test, n = 31). dpi, days postinjury; dpm, days postmanipulation; FVS, fractional volume shortening; RFVS, relative fractional volume shortening.…”
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17971
NMDA does not alter PPR but does potentiate postsynaptic responses to glycine.
Published 2019“…<p>A. Paired pulse ratio does not decrease after NMDA-induced potentiation. …”
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17972
Evolution of mutation rates on simple fitness landscapes with different ruggedness.
Published 2013“…Although the optimal mutation rate increases as a function of valley size (note the right-shift in the dashed line from top to bottom), the evolved mutation rates in fact decrease as a function of valley size (note the left-shift of the blue and red points from top to bottom).…”
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17973
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17974
Inhibitors of 5-LOX block TRPM7-mediated cell rounding.
Published 2010“…An asterisk indicates treatments that produced a decrease in cell rounding that was significantly different from 293-TRPM7 cells grown in tetracycline.…”
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17975
Cacao Cultivation under Diverse Shade Tree Cover Allows High Carbon Storage and Sequestration without Yield Losses
Published 2016“…Despite a canopy cover increase from 50 to 93%, cacao bean yield remained invariant across the systems (variation: 1.1–1.2 Mg C ha<sup>-1</sup> yr<sup>-1</sup>). …”
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17976
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17977
Influence of Kar4 deletion on low affinity PRE sites.
Published 2025“…</b> Dynamics of nuclear enrichment of WT (solid lines) and <i>kar4∆</i> cells (dashed lines) with a synthetic promoter with 2 PREs spaced by 3 bp in tail-to-tail orientation and where one of the PRE sequences has been mutated to decrease the affinity to Ste12. …”
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17978
Effects of 1,25(OH)<sub>2</sub>D<sub>3</sub> on transendothelial electrical resistance (TEER) in bEnd.3 cells under hypoxia/reoxygenation (H/R).
Published 2015“…<p><b>(A)</b> TEER was decreased by H/R. The decrease was significantly prevented by pretreatment with 1,25(OH)<sub>2</sub>D<sub>3</sub> (Vit D) at 20, 50, 100, and 200 nM. …”
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17979
High-Throughput Sequencing Reveals Differential Expression of miRNAs in Intestine from Sea Cucumber during Aestivation
Published 2013“…We identified 42 differentially expressed miRNAs [RPM (reads per million) >10, |FC| (|fold change|) ≥1, FDR (false discovery rate) <0.01] during aestivation, which were validated by two other miRNA profiling methods: miRNA microarray and real-time PCR. …”
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17980
Effects of site-specific sustained photostimulation of inhibitory neurons within the pre-Bötzinger complex <i>in situ</i>.
Published 2018“…(<b>D</b>) Summary data (n = 10, mean ± SEM, **p<0.01, *p<0.05) of bilateral pre-BötC photostimulation shows that relatively weak (0.5–2.0 mW) stimulation significantly increased respiratory frequency in a laser power-dependent manner, and stronger (4.0–5.0 mW) stimulation caused a decrease of inspiratory frequency with complete termination of inspiratory activity for the stimulus duration at the maximum laser power (5.0 mW).…”