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Na + /H + exchanger isoform 1-induced osteopontin expression facilitates cardiac hypertrophy through p90 ribosomal S6 kinase
Published 2018“…Moreover, NHE1 transgenic mice also showed increased collagen deposition, upregulation of CD44 and phosphorylation of p90 ribosomal s6 kinase (RSK), effects that were regressed in OPN knockout mice. In conclusion, we developed an interesting comparative model of active NHE1 transgenic mouse lines which express a dilated hypertrophic phenotype expressing CD44 and phosphorylated RSK, effects which were regressed in absence of OPN.…”
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703
Privacy-preserving federated learning cyber-threat detection for intelligent transport systems with blockchain-based security
Published 2022“…Subsequently, by using blockchain and by applying an aggregation strategy to different models, models from the previous step were uploaded in a smart contract. Lastly, we returned the updated models to the vehicles. …”
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704
Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice
Published 2024“…These findings were found to be correlated with increased level of oxidative stress, neuroinflammation, and apoptosis markers, and reduced expression of brain-derived neurotrophic factor (BDNF), which plays an essential role in modulating synaptic plasticity integral for promoting learning and memory in the hippocampus. Additionally, we showed that AB-FUBINACA significantly decreased the expression of NR1, an important functional subunit of glutamate/NMDA receptors and closely implicated in the development of toxic psychosis. …”
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705
Thermal and mechanical stability of microwave sintered cold compact bismuth telluride thermoelectric material
Published 2022“…The TGA-DSC results indicate a slight mass gain at 350 °C followed by a steep weight loss beyond 550 °C suggesting good thermal stability when the experimental temperature is below 350 °C. …”
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706
PRMT5-PTEN molecular pathway regulates senescence and self-renewal of primary glioblastoma neurosphere cells
Published 2017“…Our results uncover a very significant role for PRMT5 in GBMNS self-renewal capacity and proliferation. …”
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707
Deoxygenation of pyrolysis vapour derived from durian shell using catalysts prepared from industrial wastes rich in Ca, Fe, Si and Al
Published 2020“…Catalytic fast pyrolysis of durian shell using waste-derived catalysts is an effective waste management strategy as the bio-oil produced can be a potential alternative source of energy or chemical feedstocks.…”
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708
Oxidative stress cytotoxicity induced by platinum-doped magnesia nanoparticles in cancer cells
Published 2021“…Pt/MgO nanoparticles were cuboid and in the nanosize range of 30–50 nm. The cytotoxicity of Pt/MgO nanoparticles was determined via the 3-(4,5-dimethylthiazol-2-yl)−2,5-diphenyltetrazolium bromide assay on the human lung and colonic cancer cells (A549 and HT29 respectively) and normal human lung and colonic fibroblasts cells (MRC-5 and CCD-18Co repectively). …”
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709
Binary Si–Ge Alloys as High-Capacity Anodes for Li-Ion Batteries
Published 2020“…The specific charge capacity retention decreases from 97.7%, 94.5%, 88.7%, and 81.2% after 20, 30, 40, and 50 cycles, respectively. …”
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710
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Oxidative stress cytotoxicity induced by platinum-doped magnesia nanoparticles in cancer cells
Published 2021“…Pt/MgO nanoparticles were cuboid and in the nanosize range of 30–50 nm. The cytotoxicity of Pt/MgO nanoparticles was determined via the 3-(4,5-dimethylthiazol-2-yl)−2,5-diphenyltetrazolium bromide assay on the human lung and colonic cancer cells (A549 and HT29 respectively) and normal human lung and colonic fibroblasts cells (MRC-5 and CCD-18Co repectively). …”
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Combined Noncoding RNA-mRNA Regulomics Signature in Reprogramming and Pluripotency in iPSCs
Published 2022“…Moreover, miRNA, piRNA, and snoRNAs expression profiles in iPSCs and original fibroblasts were assessed to identify the potential role of ncRNAs in enhancing iPSC generation, pluripotency, and differentiation. Decreased levels of let-7a-5p showed an increase of SP8 as described previously. …”
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716
Propagation rate coefficient for sulfobetaine monomers by PLP-SEC
Published 2016“…The kp values are determined in aqueous solutions for monomer concentrations between 5 and 50 wt % and temperatures between 15 and 80 °C. The propagation rate for SBE is by about a factor of two higher than that for SBAm. …”
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Tandem osmotic engine based on hydrogel particles with antipolyelectrolyte and polyelectrolyte effect fuelled by both salinity gradient modes
Published 2021“…In this study, we propose a new approach to attain energy by salinity gradient engines with pistons based on hydrogels possessing polyelectrolyte and antipolyelectrolyte effects in a tandem arrangement, providing energy in each salinity gradient mode in a repeatable manner. …”
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718
The effect of type and combination of fertilizers on eukaryotic microbiome of date palm rhizosphere
Published 2024“…However, a high concentration of biofertilizer combined with a low concentration of chemical fertilizers enhanced the eukaryotic diversity within the samples. …”
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Selection of Bacillus spp. with decontamination potential on multiple Fusarium mycotoxins
Published 2021“…Complete degradation (100%) of ZEN was observed at a contamination level of 0.375 μg/ml in LB, while showing a decreasing trend of degradation (87 and 84%) at increasing levels of mycotoxins (0.750 and 1.50 μg/ml LB medium, respectively). …”
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720
Ubiquitin-Related Modifier 1 (URM-1) Modulates Cx43 in Breast Cancer Cell Lines.
Published 2023“…In particular, the PTM of connexin 43 (Cx43), a tumor suppressor protein, regulates its turnover and activity. …”
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