Salicylic Acid Derivatives Inhibit Oxalate Production in Mouse Hepatocytes with Primary Hyperoxaluria Type 1 حسب María Dolores Moya-Garzón (5597540)

"…We introduce here an unprecedented activity of salicylic acid derivatives as agents capable of decreasing oxalate output in hyperoxaluric hepatocytes at the low micromolar range, which means a potential use in the treatment of PH1. …"

Multiple homologs of 16p12.1 genes contribute to neurodevelopmental defects in <i>Drosophila melanogaster</i> and <i>X</i>. <i>laevis</i>. حسب Lucilla Pizzo (2735491)

"…<i>laevis</i> represents controls injected with the highest amount of morpholino (50 ng, see <b><a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009112#pgen.1009112.s005" target="_blank">S5 Fig</a></b>). …"

STAT1-regulated expression of <i>ido</i> is involved in the control of <i>T. cruzi</i> infection. حسب Philipp Stahl (443447)

"…Equal numbers of HFF and A549 cells were either pre-treated with 5 ng/ml of IFNγ or challenged for 18 h with parasites at an MOI of 15, in the absence or presence of AG-490 (50 µM). …"

Table_3_Puerarin Alleviates Vascular Cognitive Impairment in Vascular Dementia Rats.XLSX حسب Tiantian Zhu (8254053)

"…Rats with BCCAO developed VD. Pur (50, 100, and 150 mg/kg) dose-dependently attenuated the pathological changes, increased synaptic structural plasticity in the dorsal CA1 hippocampal region and decreased oxidative stress, which eventually reduced cognitive impairment and vascular injury in BCCAO rats. …"

Image_1_Puerarin Alleviates Vascular Cognitive Impairment in Vascular Dementia Rats.TIF حسب Tiantian Zhu (8254053)

"…Rats with BCCAO developed VD. Pur (50, 100, and 150 mg/kg) dose-dependently attenuated the pathological changes, increased synaptic structural plasticity in the dorsal CA1 hippocampal region and decreased oxidative stress, which eventually reduced cognitive impairment and vascular injury in BCCAO rats. …"

Table_1_Puerarin Alleviates Vascular Cognitive Impairment in Vascular Dementia Rats.docx حسب Tiantian Zhu (8254053)

"…Rats with BCCAO developed VD. Pur (50, 100, and 150 mg/kg) dose-dependently attenuated the pathological changes, increased synaptic structural plasticity in the dorsal CA1 hippocampal region and decreased oxidative stress, which eventually reduced cognitive impairment and vascular injury in BCCAO rats. …"

Table_2_Puerarin Alleviates Vascular Cognitive Impairment in Vascular Dementia Rats.xlsx حسب Tiantian Zhu (8254053)

"…Rats with BCCAO developed VD. Pur (50, 100, and 150 mg/kg) dose-dependently attenuated the pathological changes, increased synaptic structural plasticity in the dorsal CA1 hippocampal region and decreased oxidative stress, which eventually reduced cognitive impairment and vascular injury in BCCAO rats. …"

Inhibition of CFTR Cl^¯ channels by fractions from <i>Rhodiola kirilowii</i> (Regel) Maxim. حسب Lei Chen (54296)

An automated screening method for detecting compounds with goitrogenic activity using transgenic zebrafish embryos حسب Sergio Jarque (5698859)

"…<div><p>The knowledge on environmentally relevant chemicals that may interfere with thyroid signaling is scarce. Here, we present a method for the screening of goitrogens, compounds that disrupt the thyroid gland function, based on the automatic orientation of zebrafish in a glass capillary and a subsequent imaging of reporter gene fluorescence in the thyroid gland of embryos of the transgenic zebrafish line tg(tg:mCherry). …"

Self-Powered TENG with High Humidity Sensitivity from PVA Film Modified by LiCl and MXene حسب Jing Wang (6206297)

"…Short-circuit current of the TENG in a wide range of RH (from 50% to 98%) responds very sensitively to humidity fluctuations in the environment and superior adsorption–desorption performance as humidity decreases. …"

Self-Powered TENG with High Humidity Sensitivity from PVA Film Modified by LiCl and MXene حسب Jing Wang (6206297)

"…Short-circuit current of the TENG in a wide range of RH (from 50% to 98%) responds very sensitively to humidity fluctuations in the environment and superior adsorption–desorption performance as humidity decreases. …"

Potency and breadth of subject immune sera. حسب Chad D. Nix (8704143)

"…The plot for each serum shows the proportion of viruses neutralized by FRNT₅₀ at a given serum dilution. Each step in each plot represents an FRNT₅₀ value for one virus; as fold serum dilution increases for each serum, the proportion of viruses neutralized decreases by 1/11 (9.1%) as each FRNT₅₀ dilution for each virus is crossed. …"

Potent Half-Sandwich Iridium(III) Anticancer Complexes Containing C^∧N‑Chelated and Pyridine Ligands حسب Zhe Liu (77240)

"…The monodentate py ligands blocked hydrolysis; however, antiproliferative studies showed that all the Ir compounds are highly active toward A2780, A549, and MCF-7 human cancer cells. In general the introduction of an electron-donating group (e.g., Me, NMe₂) at specific positions on the pyridine ring resulted in increased antiproliferative activity, whereas electron-withdrawing groups (e.g., COMe, COOMe, CONEt₂) decreased anticancer activity. …"

5‑Aroylindoles Act as Selective Histone Deacetylase 6 Inhibitors Ameliorating Alzheimer’s Disease Phenotypes حسب Hsueh-Yun Lee (141907)

"…<i>N</i>-Hydroxy-4-((5-(4-methoxybenzoyl)-1<i>H</i>-indol-1-yl)­methyl)­benzamide (<b>6</b>) has potent inhibitory selectivity against histone deacetylase 6 (HDAC6) with an IC₅₀ value of 3.92 nM. It decreases not only the level of phosphorylation of tau proteins but also the aggregation of tau proteins. …"

Effects of Sediment Characteristics on the Toxicity of Chromium(III) and Chromium(VI) to the Amphipod, <i>Hyalella azteca</i> حسب John M. Besser (467734)

"…Waterborne Cr(VI) caused reduced survival of amphipods with a median lethal concentration (LC₅₀) of 40 μg/L. …"

Data_Sheet_1_Toxic Effects of Cd and Zn on the Photosynthetic Apparatus of the Arabidopsis halleri and Arabidopsis arenosa Pseudo-Metallophytes.PDF حسب Michał Szopiński (6806870)

"…In both plant species, exposure to high Cd or Zn induced a decrease in chlorophyll and an increase in anthocyanin contents in leaves compared to the control condition. …"

Data_Sheet_2_Toxic Effects of Cd and Zn on the Photosynthetic Apparatus of the Arabidopsis halleri and Arabidopsis arenosa Pseudo-Metallophytes.PDF حسب Michał Szopiński (6806870)

"…In both plant species, exposure to high Cd or Zn induced a decrease in chlorophyll and an increase in anthocyanin contents in leaves compared to the control condition. …"

Table_1_Toxic Effects of Cd and Zn on the Photosynthetic Apparatus of the Arabidopsis halleri and Arabidopsis arenosa Pseudo-Metallophytes.DOCX حسب Michał Szopiński (6806870)

"…In both plant species, exposure to high Cd or Zn induced a decrease in chlorophyll and an increase in anthocyanin contents in leaves compared to the control condition. …"

Table_2_Toxic Effects of Cd and Zn on the Photosynthetic Apparatus of the Arabidopsis halleri and Arabidopsis arenosa Pseudo-Metallophytes.DOCX حسب Michał Szopiński (6806870)

"…In both plant species, exposure to high Cd or Zn induced a decrease in chlorophyll and an increase in anthocyanin contents in leaves compared to the control condition. …"

Data_Sheet_3_Toxic Effects of Cd and Zn on the Photosynthetic Apparatus of the Arabidopsis halleri and Arabidopsis arenosa Pseudo-Metallophytes.PDF حسب Michał Szopiński (6806870)

"…In both plant species, exposure to high Cd or Zn induced a decrease in chlorophyll and an increase in anthocyanin contents in leaves compared to the control condition. …"