The prevalence of hypertension, diabetes, metabolic syndrome, cardiovascular disease and decreased GFR according to the following age groups: 60–69, 70–79 and ≥80 years. by Regina C. R. M. Abdulkader (302450)

“…Metabolic syndrome: presence of at least three of the following criteria: a waist circumference ≥90 cm for men or ≥80 cm for women, triglycerides ≥150 mg/dL, an HDL cholesterol ≤40 mg/dL for males or ≤50 mg/dL for females, a systolic blood pressure ≥130 mm Hg or a diastolic blood pressure ≥85 mmHg and a fasting plasma glucose ≥100 mg/dL. …”

CD4 T cell polyfunctionality inversely correlates with host susceptibility to <i>C</i>. <i>muridarum</i> in the FRT. by Miguel A. B. Mercado (17847533)

Decreasing fitness over time observed following analysis of paired isolates obtained from acute HIV-1 infection subjects, measured using QPCR. by Alicia Arnott (242179)

Combination of DNA Damage, Autophagy, and ERK Inhibition: Novel Evodiamine-Inspired Multi-Action Pt(IV) Prodrugs with High-Efficiency and Low-Toxicity Antitumor Activity by Xiao-Meng Liu (778197)

“…Among them, compound <b>10</b> exhibited a 118-fold enhancement in the IC₅₀ value compared to cisplatin and low toxicity to normal cells. …”

Combination of DNA Damage, Autophagy, and ERK Inhibition: Novel Evodiamine-Inspired Multi-Action Pt(IV) Prodrugs with High-Efficiency and Low-Toxicity Antitumor Activity by Xiao-Meng Liu (778197)

“…Among them, compound <b>10</b> exhibited a 118-fold enhancement in the IC₅₀ value compared to cisplatin and low toxicity to normal cells. …”

Combination of DNA Damage, Autophagy, and ERK Inhibition: Novel Evodiamine-Inspired Multi-Action Pt(IV) Prodrugs with High-Efficiency and Low-Toxicity Antitumor Activity by Xiao-Meng Liu (778197)

“…Among them, compound <b>10</b> exhibited a 118-fold enhancement in the IC₅₀ value compared to cisplatin and low toxicity to normal cells. …”

Combination of DNA Damage, Autophagy, and ERK Inhibition: Novel Evodiamine-Inspired Multi-Action Pt(IV) Prodrugs with High-Efficiency and Low-Toxicity Antitumor Activity by Xiao-Meng Liu (778197)

“…Among them, compound <b>10</b> exhibited a 118-fold enhancement in the IC₅₀ value compared to cisplatin and low toxicity to normal cells. …”

Combination of DNA Damage, Autophagy, and ERK Inhibition: Novel Evodiamine-Inspired Multi-Action Pt(IV) Prodrugs with High-Efficiency and Low-Toxicity Antitumor Activity by Xiao-Meng Liu (778197)

“…Among them, compound <b>10</b> exhibited a 118-fold enhancement in the IC₅₀ value compared to cisplatin and low toxicity to normal cells. …”

Thy1-p45 transgenic mice have decreased retraction of CST fibers and improved functional recovery following SCI compared to their WT littermates. by Tsung-Chang Sung (436234)

Study population: patients living with comorbidities (on the left) and immunosuppressive conditions (on the right) who are at risk of pneumococcal disease in France in the year 202... by Benjamin Wyplosz (22032756)

Anti-IL-10R blockade partially restores the ability of bacterial control in <i>Bhlhe40</i>-deficient mice. by Miguel A. B. Mercado (17847533)

The proportion of ALDH+ cells progressively increases while CGA+ cells markedly decreases in <i>APC</i>-mutant colon tissues from FAP patients. by Tao Zhang (43681)

“…<p>Representative IHC stains of normal, normal-appearing FAP, and FAP adenomatous colonic crypts are shown for the expression of the: <b>(A)</b> NEC marker chromogranin-A (CGA). <b>(B)</b> SC marker ALDH1. …”

UV-irradiated M phase-cells show decreased MCM 2–7 loading and G1 arrest after release: HeLa cells. by Masayuki Morino (304956)

LdAS-LdPEX5 interactions. by Ines Lakhal-Naouar (125773)

“…(E) Nickel agarose pull-down (PD): Left panel: protein lysates from V5His-LdASS^WT were used in a co-immunoprecipitation reaction with Anti-LdPEX5 antibody (lane 1) or preimmune sera (NRS) (lane 2) or for nickel agarose PD (lane 3) and the immuno-blot was bound with anti-LdASS antibody. …”

The Anion [Mg₆Cl₈Cp*₅]^-:  A Final Intermediate on the Way to the Molecular Donor-Free Grignard Compound MgClCp*? by Jean Vollet (2644651)

“…The reaction at −70 °C of decamethylmagnesocene MgCp*₂ (Cp* = pentamethylcyclopentadienyl) with monovalent aluminum chloride, AlCl, stabilized with diethyl ether and dissolved in toluene, results in tetrameric tetrahedrotetrakis(pentamethylcyclopentadienylaluminum), [AlCp*]₄, and the dimeric bis(pentamethylcyclopentadienylmagnesium chloride diethyl etherate), [MgCp*Cl·Et₂O]₂. At a slightly higher temperature and by stepwise decrease of the diethyl ether concentration before reaction, a preferred formation of metal clusters such as dodekakispentamethylcyclopentadienylpentaconta-aluminum, Al₅₀Cp*₁₂, was frequently observed. …”

PHA increased anti-oxidant gene expression and decreased NADPH oxidase and phospho-NF-kB p65⁺ microglia/macrophages. by Zhenying Han (621634)

<i>Bhlhe40</i> suppresses <i>Chlamydia</i>-specific Tr1 differentiation in a T cell-intrinsic manner. by Miguel A. B. Mercado (17847533)

Data_Sheet_1_Repeated Inoculation of Young Calves With Rumen Microbiota Does Not Significantly Modulate the Rumen Prokaryotic Microbiota Consistently but Decreases Diarrhea.docx by Dengpan Bu (369549)

Drop point and rebound rounds^a effects for groups in the empirical and simulated data. by Daniel B. Shank (709756)

Treatment of MCMV infected neonates with dexamethasone decreases infiltration of inflammatory cells and expression of interferon stimulated genes in the CNS without increasing leve... by Kate Kosmac (386527)