Transmural Ultrasound Imaging of Thermal Lesion and Action Potential Changes in Perfused Canine Cardiac Wedge Preparations by High Intensity Focused Ultrasound Ablation by Ziqi Wu (496313)

“…Spatiotemporally correlated AP measurements and ultrasound imaging allowed quantification of the reduction of AP amplitude (APA), shortening of AP duration at 50% repolarization, AP triangulation, decrease of optical AP rise, and change of conduction velocity along tissue depth direction within and surrounding HIFU lesions. …”

Piezo1 modulates autophagy of HT22 neurons. by Yatong Wu (13228206)

“…<p><b>(A)</b> Autophagy measured using The Autophagy Assay Kit and represented as the number of autophagic vacuoles. …”

Analysis of SMN levels in different tissues of severe SMA mice. by Francesca Gabanella (34598)

“…(C) Analysis of SMN decrease in the spinal cord of severe SMA mice. Western blot analysis of the indicated serial dilutions (100 equals 50 µg of proteins) of whole tissue extracts from the spinal cord of normal (<i>SMN2</i>^+/+;<i>mSmn</i>^+/+), carrier (<i>SMN2</i>^+/+;<i>mSmn</i>^+/−) and severe SMA (<i>SMN2</i>^+/+;<i>mSmn</i>^−/−) mice at postnatal day 3. …”

Convallatoxin suppresses osteosarcoma cell proliferation, migration, invasion, and enhances osteogenic differentiation by downregulating parathyroid hormone receptor 1 (PTHR1) expr... by Xin Liu (43569)

“…<p>Osteosarcoma (OS) is the most common primary malignant bone tumor in children and adolescents. Convallatoxin, a natural cardiac glycoside, exhibits potent anti-tumor activities. …”

Table_1_Lactose-Induced Chronic Diarrhea Results From Abnormal Luminal Microbial Fermentation and Disorder of Ion Transport in the Colon.XLS by Hong Xue (28736)

“…The concentrations of lactose, galactose and lactic acid of the cecal content were markedly increased (P < 0.01) and SCFA concentration was significantly decreased (P < 0.01). This was associated with depletion of the Lachnospiraceae NK4A136 group and Ruminococcaceae UCG-005 and increased relative abundance of Lactobacillus, escherichia-shigella and megamonas in the cecal microbiota. …”

Data Sheet 1_High intensity human activity limits ultra-high altitude soil microbial community dispersal and keystone taxa distribution in southeastern Tibetan Plateau.docx by Wenzu Liu (22364023)

“…Human activities increase the complexity of microbial networks but decrease the stability of soil micro-ecosystems. As elevtation increases, the dispersal limitation of microbial communities decreases (total effect size: bacterial = −0.705, fungal = −0.745). …”

Histological analysis for neurons and myelin. by Svitlana Garbuzova-Davis (81764)

“…Contralateral striatosomes also showed size decreases similar to striatosomes within infarct area. …”

An <i>in-silico</i> analysis to identify structural, functional and regulatory role of SNPs in <i>hMRE11</i> by Bhoomi Tarapara (11977197)

“…<p>Meiotic recombination 11 (<i>MRE11</i>) is a component of the tri-molecular <i>MRE11</i>-RAD50-NBS1 (MRN) complex, which functions as an exonuclease and endonuclease which is involved in identifying, signalling, protecting and repairing double-strand breaks in DNA (DSBs). …”

DataSheet_1_Effects of the neurotoxin β-N-methylamino-L-alanine (BMAA) on the early embryonic development of marine shellfish and fish.docx by Yilei Fu (14287574)

“…A sustained and dose-dependent decrease in heart rate was apparent in marine medaka embryos at 9-days post fertilization following BMAA exposure. …”

Data Sheet 3_Cepharanthine may inhibit the proliferation of prostate cells by blocking the EGFR/PI3K/AKT signaling pathway: comprehensive network analysis, molecular docking, and e... by Yin Huang (179237)

“…In vitro experiments showed that CEP inhibited WPMY-1 (IC₅₀ = 6.396 μM) and BPH-1 (IC₅₀ = 2.355 μM) proliferation in a dose-dependent manner. …”

Data Sheet 4_Cepharanthine may inhibit the proliferation of prostate cells by blocking the EGFR/PI3K/AKT signaling pathway: comprehensive network analysis, molecular docking, and e... by Yin Huang (179237)

“…In vitro experiments showed that CEP inhibited WPMY-1 (IC₅₀ = 6.396 μM) and BPH-1 (IC₅₀ = 2.355 μM) proliferation in a dose-dependent manner. …”

Table_5_Systemic immunological profile of children with B-cell acute lymphoblastic leukemia: performance of cell populations and soluble mediators as serum biomarkers.docx by Maria Perpétuo Socorro Sampaio Carvalho (7300568)

Data Sheet 2_Cepharanthine may inhibit the proliferation of prostate cells by blocking the EGFR/PI3K/AKT signaling pathway: comprehensive network analysis, molecular docking, and e... by Yin Huang (179237)

“…In vitro experiments showed that CEP inhibited WPMY-1 (IC₅₀ = 6.396 μM) and BPH-1 (IC₅₀ = 2.355 μM) proliferation in a dose-dependent manner. …”

Data Sheet 1_Cepharanthine may inhibit the proliferation of prostate cells by blocking the EGFR/PI3K/AKT signaling pathway: comprehensive network analysis, molecular docking, and e... by Yin Huang (179237)

“…In vitro experiments showed that CEP inhibited WPMY-1 (IC₅₀ = 6.396 μM) and BPH-1 (IC₅₀ = 2.355 μM) proliferation in a dose-dependent manner. …”

Table 1_Body mass index influences Antimüllerian Hormone and inhibin B in adult males.xls by Wen Zhou (49050)

“…In the fully adjusted model, the increase in BMI in Q4 was linked to decreases of 1.62 ng ml-1 in AMH and 18.20 pg ml^-1 in INHB, but these associations were not statistically significant (P>0.05). …”

Synaptic boutons located on the same axon have similar endogenous Ca²⁺ buffering capacity. by Yaroslav S. Ermolyuk (135824)

“…Right, peak-scaled Ca²⁺ fluorescence traces illustrating an increase of the fast fluorescence decay component and a decrease of the slow fluorescence decay component with the increase of the endogenous Ca²⁺ buffer concentration. …”

Data_Sheet_1_Response of Nitrate Processing to Bio-labile Dissolved Organic Matter Supply Under Variable Oxygen Conditions in a Sandy Beach Seepage Face.PDF by Shan Jiang (121292)

“…Sediment microbiota information suggests that nitrification (e.g., Nitrosomonas and Nitrososphaera) and denitrification (e.g., Marinobacter and Bacillus) were dominant pathways for benthic NO₃^– production and removal in the studied sediment. …”

Data_Sheet_2_The burden of epilepsy in the People’s Republic of China from 1990 to 2019: epidemiological trends and comparison with the global burden of epilepsy.PDF by Yun Shu (2016445)

“…Background<p>Epilepsy is associated with a significant global burden of disease, affecting over 50 million people worldwide. …”

Comparison of autonomic stress reactivity in young healthy versus aging subjects with heart disease by Nil Z. Gurel (6681047)

“…</p><p>Results</p><p>Mental stress reduced PEP in both groups (p<0.01), although the decrease was 50% greater in the healthy group. Mean HF HRV decreased significantly in the aging group only (p = 0.01).…”

fdata-01-00004-g0006_Systematic Lab Knowledge Integration for Management of Lipid Excess in High-Risk Patients: Rationale and Design of the SKIM LEAN Project.tif by Chiara Pavanello (4846771)

“…Metrics to verify the project achievements include web-site visits, the number of alerts generated, numbers of patients referred by GPs, the proportion of secondary prevention patients who achieve LDL-C <100 mg/dl or a >50% decrease from baseline.</p>…”