The effect of glibenclamide on channel activity at +20, 0 and -20 mV. by Sajjad Salari (736104)

“…Histogram bars show current amplitudes and P_o of reconstituted channels in absence or presence of glibenclamide. The addition of 50 μM glibenclamide resulted in a decreased current jump amplitude and a reduction in P_o. 100 μM glibenclamide caused a total channel inhibition at +20 and 0 mV (n = 5), but was ineffective at -20 mV. …”

Image_3_DNMT3A R882 Mutations Confer Unique Clinicopathologic Features in MDS Including a High Risk of AML Transformation.tif by Majd Jawad (12157533)

“…By data mining with publicly accessible cancer genomics databases and a clinical genomic database from a tertiary medical institution, DNMT3A R882 mutations were found to be enriched in AML (53% of all DNMT3A mutations) but decreased in frequency in clonal hematopoiesis of indeterminate potential (CHIP) (10.6%) or other myeloid neoplasms including MDS (27%) (p<.001). …”

Image_1_DNMT3A R882 Mutations Confer Unique Clinicopathologic Features in MDS Including a High Risk of AML Transformation.tif by Majd Jawad (12157533)

“…By data mining with publicly accessible cancer genomics databases and a clinical genomic database from a tertiary medical institution, DNMT3A R882 mutations were found to be enriched in AML (53% of all DNMT3A mutations) but decreased in frequency in clonal hematopoiesis of indeterminate potential (CHIP) (10.6%) or other myeloid neoplasms including MDS (27%) (p<.001). …”

Crystal Structure of YbCu₆In₆ and Mixed Valence Behavior of Yb in YbCu_6–<i>x</i>In_6+<i>x</i> (<i>x</i> = 0, 1, and 2) Solid Solution by Udumula Subbarao (1431364)

“…A deviation in inverse susceptibility data at 200 K suggests a valence transition from Yb²⁺ to Yb³⁺ as the temperature decreases. …”

Image_2_DNMT3A R882 Mutations Confer Unique Clinicopathologic Features in MDS Including a High Risk of AML Transformation.tif by Majd Jawad (12157533)

“…By data mining with publicly accessible cancer genomics databases and a clinical genomic database from a tertiary medical institution, DNMT3A R882 mutations were found to be enriched in AML (53% of all DNMT3A mutations) but decreased in frequency in clonal hematopoiesis of indeterminate potential (CHIP) (10.6%) or other myeloid neoplasms including MDS (27%) (p<.001). …”

Table_2_DNMT3A R882 Mutations Confer Unique Clinicopathologic Features in MDS Including a High Risk of AML Transformation.docx by Majd Jawad (12157533)

“…By data mining with publicly accessible cancer genomics databases and a clinical genomic database from a tertiary medical institution, DNMT3A R882 mutations were found to be enriched in AML (53% of all DNMT3A mutations) but decreased in frequency in clonal hematopoiesis of indeterminate potential (CHIP) (10.6%) or other myeloid neoplasms including MDS (27%) (p<.001). …”

Table_1_DNMT3A R882 Mutations Confer Unique Clinicopathologic Features in MDS Including a High Risk of AML Transformation.docx by Majd Jawad (12157533)

“…By data mining with publicly accessible cancer genomics databases and a clinical genomic database from a tertiary medical institution, DNMT3A R882 mutations were found to be enriched in AML (53% of all DNMT3A mutations) but decreased in frequency in clonal hematopoiesis of indeterminate potential (CHIP) (10.6%) or other myeloid neoplasms including MDS (27%) (p<.001). …”

Study flow and included patients. by Chung-Yeh Chuang (15285925)

“…In the multivariate analysis, being underweight (adjust OR [aOR], 3.80, compared to normoweight; 95% CI, 1.23–11.7) and lower maximal inspiratory airway pressure (aOR per one cmH₂O decrease, 1.05; 95% CI 1.00–1.09) remained significantly associated with extubation failure.…”

Weaning parameters before planned extubation. by Chung-Yeh Chuang (15285925)

“…In the multivariate analysis, being underweight (adjust OR [aOR], 3.80, compared to normoweight; 95% CI, 1.23–11.7) and lower maximal inspiratory airway pressure (aOR per one cmH₂O decrease, 1.05; 95% CI 1.00–1.09) remained significantly associated with extubation failure.…”

S1 Data - by Chung-Yeh Chuang (15285925)

“…In the multivariate analysis, being underweight (adjust OR [aOR], 3.80, compared to normoweight; 95% CI, 1.23–11.7) and lower maximal inspiratory airway pressure (aOR per one cmH₂O decrease, 1.05; 95% CI 1.00–1.09) remained significantly associated with extubation failure.…”

Baseline characteristics of enrolled patients. by Chung-Yeh Chuang (15285925)

“…In the multivariate analysis, being underweight (adjust OR [aOR], 3.80, compared to normoweight; 95% CI, 1.23–11.7) and lower maximal inspiratory airway pressure (aOR per one cmH₂O decrease, 1.05; 95% CI 1.00–1.09) remained significantly associated with extubation failure.…”

Inhibition of Acetyl-CoA Carboxylase 1 (ACC1) and 2 (ACC2) Reduces Proliferation and <i>De Novo</i> Lipogenesis of EGFRvIII Human Glioblastoma Cells by Jessica E. C. Jones (541168)

Depletion of SAMHD1 leads to increased DNA damage. by Kiwon Park (6492266)

S1 Data - by Mariana Paschoalini (8748660)

Fig 7 - by Cristoforo Simonetto (563944)

Relative abundances of <i>L</i>. <i>iners</i> proteins in cervicovaginal lavages of women with positive <i>L</i>. <i>iners</i> 16S rDNA microarray results (n = 31) among three cerv... by Hanneke Borgdorff (620183)

“…Outliers are plotted as points. *p-value<0.05; ** p-value<0.01; ***p-value<0.001. …”

Melanoregulin levels influence melanosome characteristics in the choroid of <i>Hps5^ru2J</i> and <i>Oa1</i> mutant mice. by Rivka A. Rachel (137639)

“…<p>Quantitation and analysis of the data shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0042446#pone-0042446-g004" target="_blank">Figure 4</a>. Data points are mean values ± SEM. A. Melanosome number and B. …”

Demonstration that SP-1 and SP-3 negatively regulates the PP2A-Aα promoter. by He-Ge Chen (90952)

“…Expression of the exogenous pCMV-SP-1 in both types of ocular cells attenuated expression of the endogenous gene coding for PP2A-Aα. F. Expression of the exogenous SP-3 in both types of ocular cells induced only slight decrease in the luciferase reporter gene activity within 0 to 500 ng of the pCMV-SP-3 plasmid, which is not statistically significant. …”

Modulation of Aβ-induced deleterious signaling. by Tao Yang (184280)

“…(H) In DIV 21–22 hippocampal neuronal cultures examined at the 3 hour time point, Aβ significantly decreased CREB phosphorylation by 43%, while this decrease was prevented by LM11A-24 and -31 (n = 10 separate Western blots from 5 independent protein preparations).…”

Charge Distribution in Cationic Molybdenum Imido Alkylidene <i>N</i>‑Heterocyclic Carbene Complexes: A Combined X‑ray, XAS, XES, DFT, Mössbauer, and Catalysis Approach by Mathis Benedikter (9726148)

“…The binding situation in the corresponding cationic complexes Mo­(<i>N</i>-2,6-Me₂C₆H₃)­(CHCMe₂Ph)­(NHC)­(OC­(CF₃)₃)⁺ B­(Ar^F)₄^– (NHC = IMes (<b>1</b>), IMesCl₂ (<b>2</b>), IMesMe₂ (<b>3</b>), and IMesH₂ (<b>4</b>) was compared to that of the analogous neutral Schrock catalyst Mo­(<i>N</i>-2,6-Me₂C₆H₃)­(CHCMe₂Ph)­((OC­(CF₃)₃))₂ (<b>5</b>). Single-crystal X-ray data were used as a starting point for the optimization of the geometries of the catalysts at the PBE0-D3BJ/def2-SVP level of theory; the obtained data were compared to those obtained from X-ray absorption (XAS) and emission spectroscopy (XES). …”