ACY-1083 improves the epithelial integrity in fully differentiated HBEC ALI cultures challenged with different barrier disruptors. by Jenny Horndahl (10478701)

Trichopsistides A and B: Two Highly Oxygenated Pentacyclic Polyketides with Promising Inhibitory Effects on the NF-κB Signaling Pathway from the Fungus <i>Trichoderma koningiopsis<... by Li Feng (77923)

“…Two highly oxygenated pentacyclic polyketides with two new carbon skeletons, trichopsistide A (<b>1</b>) and trichopsistide B (<b>2</b>), were isolated from the plant endophyte <i>Trichoderma koningiopsis</i> WZ-196 derived from the leaf of <i>Rubia podantha</i> Diels. …”

A study of the abundance of species in grassland-to-pond transition zone and impermeable ground habitats by Helen Musulan (3119433)

“…The survey involved running a transect for 50m (parallel to the pond) and a surveyor visually inspecting and counting for the above listed species in an area within a 50m radius of the transect start point. …”

Clinical outcomes and mortality in old and very old patients undergoing cardiac resynchronization therapy by Luiz Eduardo Montenegro Camanho (8066762)

“…<div><p>Aim</p><p>Cardiac resynchronization therapy (CRT) is a valid therapeutic option for patients with heart failure (HF). …”

Table_1_Guanidine acetic acid exhibited greater growth performance in younger (13–30 kg) than in older (30–50 kg) lambs under high-concentrate feedlotting pattern.docx by Wen-Juan Li (1444948)

“…In a brief, the results obtained in the present study suggested that GAA (UGAA and CGAA; 1 g/kg DM) could be applied to improve growth performance in younger (13–30 kg) instead of older (30–50 kg) lambs in high-concentrate feedlotting practice.…”

Discovery of PMSA Derivative <b>11</b> as a Novel Lead Compound for Therapeutic Treatment of Osteoporosis <i>In Vitro</i> and <i>In Vivo</i> by Zhihao Chen (513264)

“…Additionally, <b>11</b> blocked the formation of F-action belts and bone resorption in a concentration-dependent manner. Mechanistically, <b>11</b> decreased the expression of genes required for osteoclastogenesis by blocking NFATc1 translocation from the cytoplasm to nucleus. …”

Penidaleodiolides A and B, Cage-Like Polyketides with Neurotransmission-Regulating Activity from the Soil Fungus <i>Penicillium daleae</i> L3SO by Qing-Yuan Wang (11571890)

“…The hypothetical biosynthetic pathways for <b>1</b> and <b>2</b> were postulated and were supported by CRISPR/Cas9 genome editing results. Penidaleodiolide A (<b>1</b>) showed a significant inhibitory effect on the action potentials of murine hippocampal basket neurons and decreased the frequency of spontaneous excitatory postsynaptic currents in a concentration-dependent manner (the inhibition ratios were 0.30 ± 0.02 for 1 μM, 0.37 ± 0.03 for 10 μM, and 0.50 ± 0.07 for 20 μM) while being devoid of cytotoxicity against the nerve cells.…”

Analysis of fatty infiltration in muscle MRIs. by Sebastián Figueroa-Bonaparte (3202491)

“…We observed predominant fatty infiltration in the posterior muscles of the thighs producing decreased strength in the knee flexion test. (C) There was a strong correlation between knee flexion strength and the degree of muscle fatty infiltration calculated both using 3-point Dixon (left) and the Mercuri scale (right). …”

A novel second-generation platinum derivative and evaluation of its anti-cancer potential by Habibe Yilmaz (4865200)

“…In this study, cis-4-hydroxyphenylplatinum (II) diamine was synthesized with a yield of 62%. The MTT assay on A549-Luc and SKOV3-Luc cell lines resulted in IC50 values of 17.82 and 7.81 μM, respectively. …”

Flow chart of study cohort undergoing open or minimally invasive colostomy reversal from 2012–2022. by Kevin Tabibian (21601494)

Mitochondrial Dysfunction in Human Leukemic Stem/Progenitor Cells upon Loss of RAC2 by Marta E. Capala (652765)

“…Downregulation of SAM50 also impaired the proliferation and replating capacity of BCR-ABL-expressing cells, again associated with a decreased mitochondrial membrane potential. …”

Failure time prediction results of thawed sandstone with different freezing temperatures: by Liang Zhang (41392)

MOLM14 cells incubated with Eltrombopag for 6 hours show higher expression of stress response genes. by Anna Kalota (7415)

Analysis of Research Activity in Gastroenterology: Pancreatitis Is in Real Danger - Fig 2 by Andrea Szentesi (3239193)

High-frequency (HF) EP DBS produces frequency band-specific and time-dependent increases and decreases in LFP oscillation power in primary motor cortex (M1), striatum (STR) and ven... by Clinton B. McCracken (599113)

Measuring gut motility using kymography. by Jessica C. M. Hui (20370522)

Effects of the selective TrkA agonist gambogic amide on pigmentation and growth of human hair follicles <i>in vitro</i> - Fig 4 by Remo Campiche (3714208)

“…Hair follicles treated with lower concentrations of Gambogic Amide kept their anagen-like appearance. Bars = 50 μm. <b>E: Immunohistochemical quantification of melanocytes with p16, a marker for mature and senescent melanocytes</b>. …”

Effects of GLSF and GLS gastrointestinal juice extracts on cell viability and transformation in JB6 P+ cell line. by Ayaz Shahid (12269599)

DataSheet_1_Decreased monocyte-to-lymphocyte ratio was associated with satisfied outcomes of first-line PD-1 inhibitors plus chemotherapy in stage IIIB-IV non-small cell lung cance... by Liang Zheng (206933)

“…Patients with decreased MLR had a significantly higher ORR in the univariate (P<0.001) and multivariate (P<0.001) Cox proportional hazards models. …”

Cilostazol inhibits endothelin-induced calcium increase and vasoconstriction in mouse intracranial arteries. a. by Yoshifumi Kawanabe (308848)

“…Arrows denote basilar artery constriction. Bar = 50 µm <b>c.</b> Cilostazol significantly decreases endothelin-induced cytosolic calcium increase. …”