Epigallocatechin-3-Gallate as a Potential Therapeutic Drug for TTR-Related Amyloidosis: “In Vivo” Evidence from FAP Mice Models by Nelson Ferreira (188837)

“…However, less invasive and more reliable therapeutic approaches have been proposed for FAP therapy, namely based on drugs acting as inhibitors of amyloid formation or as amyloid disruptors. We have recently reported that epigallocatechin-3-gallate (EGCG), the most abundant catechin in green tea, is able to inhibit TTR aggregation and fibril formation, “in vitro” and in a cellular system, and is also able to disrupt pre-formed amyloid fibrils “in vitro”.…”

Conceptual scheme illustrating the sCSC algorithm. by Brooke E. Husic (5921924)

Proposed Model of generating nonmotility-related mutants. by Mei Luo (773169)

Enhanced Biological Behavior of <i>In Vitro</i> Human Gingival Fibroblasts on Cold Plasma-Treated Zirconia by Miao Zheng (812392)

“…Fibroblasts density, morphology, morphometry and attachment-related genes expression were measured at different time points from 3 to 72 h.</p><p>Results</p><p>After plasma treatment, the surface morphology and roughness remained the same, while the contact angle decreased from 78.31° to 43.71°, and the surface C/O ratio decreased from 3.17 to 0.89. …”

Nakasone. AJP supple Table1, 2, 3 by Toru Aizawa (9001298)

“…<em>Hazard ratio and 95%CI of HGI and HbA1c to incident CKD</em></p> <p>  </p> <p>The data was obtained in Aizawa cohort, in which QR of HGI and HbA1c was almost the same as 0.48 and 0.50 (Table 1) so that scaling was omitted. …”

Apoptotic gene expression induced by propofol. by Yali Ge (417371)

Apoptotic gene expression without significant changes induced by propofol. by Yali Ge (417371)

Differentially expressed genes involved in Wnt signaling pathway in zebrafish spinal cord after injury and validation of <i>wnt8a</i>, <i>wnt4b</i>, <i>wnt7a</i> and <i>b- catenin<... by Subhra Prakash Hui (510710)

“…The color chart indicates mean fold change of gene expression in each time points. Red and green colors represent increased and decreased expression respectively. …”

Supplemental data about the effect of M₄N on energy metabolism. by Kotohiko Kimura (1888807)

<i>C</i>. <i>sinensis</i> promoted the expressions of cytokines in liver and BECs through TLR2 pathway. by Yuru Wang (846969)

Evaluating competitive inhibition by gcn5-F221A using a synthetic pPHO5-yECitrine construct. by Amanda M. Lanza (168454)

“…Increasing expression of <i>gcn5-F221A</i> resulted in decreased mean fluorescence. …”

The impact of nano-curcumin on cell viability and proliferation in breast cancer cells. by Taraneh Givi (22793530)

“…Cell viability significantly decreased at all tested time points. (E, F) mRNA Expression levels <i>PI3K</i>, <i>AKT1</i>, <i>mTOR</i>, <i>NF-KB</i>, <i>Cyclin D1</i>, <i>DILA1</i> and <i>PTEN</i> in breast cancer cells. …”

VER-155008 caused a significant reduction in viral transcripts in HEK-293T rKSHV.219 cells. by Belinda Baquero-Pérez (706834)

“…(C) At 4 h AcD treatment <i>SRAG</i> mRNA levels were reduced by 50% showing a relatively short stability. (D) <i>H2A</i>.…”

PIF4 protein level regulates <i>PIF4</i> promoter activity in a temperature-dependent manner. by Sreya Das (20531295)

TLR2 deficiency alleviated liver fibrosis in <i>C</i>. <i>sinensis-</i>infected mice. by Yuru Wang (846969)

<i>C</i>. <i>sinensis</i> ESPs increased the production of IL-6 via TLR2-mediated AKT and p38 pathways. by Yuru Wang (846969)

Table_1_Predictive Value of Geriatric Nutritional Risk Index in Patients With Coronary Artery Disease: A Meta-Analysis.pdf by Yu Fan (111503)

“…Furthermore, per point decrease in GNRI was associated with 8 and 10% additional risk of all-cause mortality and MACEs. …”

<i>fahd-1(tm5005) C</i>. <i>elegans</i> have a locomotion deficit. by Andrea Taferner (782532)

“…(B) 4-day old wild type and <i>fahd-1(tm5005)</i> worms were put in the center of an NGM plate seeded with <i>E</i>. <i>coli</i> OP50. The radial dispersal rate (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0134161#sec002" target="_blank">Materials and Methods</a>) was determined for three different time points (30 sec, 1 min, 2 min). …”

Image_1_Exploring the potential of pheophorbide A, a chlorophyll-derived compound in modulating GLUT for maintaining glucose homeostasis.pdf by Saptadipa Paul (18132904)

“…To assess how pheophorbide A mechanistically acts on GLUT1 in pancreatic β cell, we transfected INS-1 cells with GLUT1–enhanced green fluorescent protein and checked how the treatment of pheophorbide A (0.50 µM) modulates GLUT1 trafficking using live-cell imaging. …”

Impact of age on sharing of top 5000 TCRβ clones. by Sarah A. Johnson (11355817)