Datasheet1_A novel αB-crystallin R123W variant drives hypertrophic cardiomyopathy by promoting maladaptive calcium-dependent signal transduction.pdf by Chun Chou (16444026)

“…Recently, we identified a novel variant of the alpha-crystallin B chain (CRYAB^R123W) in a pair of monozygotic twins who developed concordant HCM phenotypes that manifested over a nearly identical time course. …”

Hydrogel particles remain in the lungs for multiple days without overt signs of inflammation. by Reid A. Roberts (334465)

“…<b>F)</b> All types of hydrogel particles can still be seen in BALF cells seven days after treatment, though there is a marked decrease in the number of particles present as compared to the 2 day time point. …”

KLK6 promotes survival of Jurkat T cells in part by slowing the apoptotic cascade. by Isobel A. Scarisbrick (354022)

“…Under resting conditions (A), and in the presence of camptothecin (B, 1.0 µM), ConA (C, 5 µg/ml), or ConA plus camptothecin (D), KLK6 (10 µg/ml) promoted an increase in the percentage of live cells (unlabeled) and a decrease in the percentage of dead cells (Annexin V⁺ and 7AAD⁺) at both acute (4 hr), subacute (24 hr), and in some cases the more chronic time point examined (48 hr). …”

Effect of TAC on left ventricular hypertrophy and function as measured by Echocardiography. by Eman A. Hamad (316682)

“…*p<0.01 vs WT TAC at the same time point. (B &C) WT mice developed into a significant increase in end systolic dimensions (B) and a higher heart weight to body weight ratio (C).…”

Data_Sheet_1_Role of hypothetical protein PA1-LRP in antibacterial activity of endolysin from a new Pantoea phage PA1.docx by Ye Tian (220278)

“…After 24 h of incubation, compared to pET28a-LRP, the OD₆₀₀ value of pET28a-Lys-LRP decreased by 0.444, while the OD₄₂₀ value increased by 3.121. …”

Transgenic expression of lamin A in <i>Lmna</i>^−/− cardiomyocytes partially restores ERK1/2 activation and gap junction protein localization. by Richard L. Frock (143372)

“…<p>(A) Western blot analysis of <i>Lmna</i>^+/+, <i>Lmna</i>^−/−, and <i>Lmna</i>^−/−; Tg mouse heart lysates. …”

Probability of localization in 93.5 dB re 1 <i>μ</i>Pa root median square noise. by Regina A. Guazzo (4543420)

“…<p>This map shows the probability of localization of a call produced at locations close to the hydrophone array in 93.5 dB re 1 <i>μ</i>Pa root median square background noise. …”

Operant self-stimulation of nigral dopamine neurons. by Mark A. Rossi (348414)

“…Self-stimulation behavior did not decrease when the animals received a second session immediately after the first. …”

The effect of brown rice compared to white rice on adiposity indices, lipid profile, and glycemic markers: a systematic review and meta-analysis of randomized controlled trials by Mahdieh Golzarand (10711904)

“…<p>A few randomized controlled trials (RCTs) have assessed the effect of brown rice consumption on metabolic parameters compared to white rice, with inconsistent findings. …”

Table_1_Efficacy of intra-arterial chemotherapy with sequential anti-PD-1 antibody in unresectable gastric cancer: A retrospective real-world study.docx by Xiaosong Xiang (14330715)

Table_1_Serum anti-Müllerian hormone levels are associated with perinatal outcomes in women undergoing IVF/ICSI: A multicenter retrospective cohort study.docx by Yi-Chen He (10726505)

“…</p>Results<p>Among women with singleton deliveries, low and high AMH levels increased the risk of intrahepatic cholestasis of pregnancy (ICP) (aOR1 = 6.02, 95%CI: 2.10-17.22; aOR2 = 3.65, 95%CI:1.32-10.08) and decreased the risk of macrosomia (aOR1 = 0.65, 95%CI:0.48-0.89; aOR2 = 0.72, 95%CI:0.57-0.96), while low AMH reduced the risk of large for gestational age (LGA, aOR=0.74, 95%CI:0.59-0.93) and premature rupture of membrane (PROM, aOR=0.50, 95%CI:0.31-0.79)compared with the average AMH group. …”

22C4 scFv inhibits Aβ_1-42 aggregation and neurotoxicity in vitro without binding to full length APP. by Susann Cattepoel (225693)

“…The addition of 22C4 scFv significantly decreased cell death indicating that it inhibited Aβ_1-42 neurotoxicity (*** p<0.005). …”

MYK-461 reduces contractility in feline HCM in an exposure-dependent manner. by Joshua A. Stern (819269)

Table_3_Efficacy of comprehensive unit-based safety program to prevent ventilator associated-pneumonia for mechanically ventilated patients in China: A propensity-matched analysis.... by Xiaomeng Yi (14262062)

“…The results of the joinpoint regression analysis confirmed that the implementation of CUSP significantly decreased the incidences of VAP. After propensity score matching in TICU setting, the CUSP group reported a lower incidence of VAP (30.4 vs. 9.7‰, P = 0.003; adjusted OR = 0.26, 95% CI: 0.10–0.76), lower wound infection (3.4 vs. 0.9%, P = 0.048; adjusted OR = 0.73, 95% CI: 0.50–0.95), shorter ICU LOS [3.5(2.3–5.3) vs. 2.5(2.0–4.5) days; P = 0.003, adjusted estimate = −0.34, 95% CI: −0.92 to −0.14], and higher safety culture score (149.40 ± 11.74 vs. 153.37 ± 9.74; P = 0.002). …”

Table_4_Efficacy of comprehensive unit-based safety program to prevent ventilator associated-pneumonia for mechanically ventilated patients in China: A propensity-matched analysis.... by Xiaomeng Yi (14262062)

“…The results of the joinpoint regression analysis confirmed that the implementation of CUSP significantly decreased the incidences of VAP. After propensity score matching in TICU setting, the CUSP group reported a lower incidence of VAP (30.4 vs. 9.7‰, P = 0.003; adjusted OR = 0.26, 95% CI: 0.10–0.76), lower wound infection (3.4 vs. 0.9%, P = 0.048; adjusted OR = 0.73, 95% CI: 0.50–0.95), shorter ICU LOS [3.5(2.3–5.3) vs. 2.5(2.0–4.5) days; P = 0.003, adjusted estimate = −0.34, 95% CI: −0.92 to −0.14], and higher safety culture score (149.40 ± 11.74 vs. 153.37 ± 9.74; P = 0.002). …”

Table_2_Efficacy of comprehensive unit-based safety program to prevent ventilator associated-pneumonia for mechanically ventilated patients in China: A propensity-matched analysis.... by Xiaomeng Yi (14262062)

“…The results of the joinpoint regression analysis confirmed that the implementation of CUSP significantly decreased the incidences of VAP. After propensity score matching in TICU setting, the CUSP group reported a lower incidence of VAP (30.4 vs. 9.7‰, P = 0.003; adjusted OR = 0.26, 95% CI: 0.10–0.76), lower wound infection (3.4 vs. 0.9%, P = 0.048; adjusted OR = 0.73, 95% CI: 0.50–0.95), shorter ICU LOS [3.5(2.3–5.3) vs. 2.5(2.0–4.5) days; P = 0.003, adjusted estimate = −0.34, 95% CI: −0.92 to −0.14], and higher safety culture score (149.40 ± 11.74 vs. 153.37 ± 9.74; P = 0.002). …”

Table_1_Efficacy of comprehensive unit-based safety program to prevent ventilator associated-pneumonia for mechanically ventilated patients in China: A propensity-matched analysis.... by Xiaomeng Yi (14262062)

“…The results of the joinpoint regression analysis confirmed that the implementation of CUSP significantly decreased the incidences of VAP. After propensity score matching in TICU setting, the CUSP group reported a lower incidence of VAP (30.4 vs. 9.7‰, P = 0.003; adjusted OR = 0.26, 95% CI: 0.10–0.76), lower wound infection (3.4 vs. 0.9%, P = 0.048; adjusted OR = 0.73, 95% CI: 0.50–0.95), shorter ICU LOS [3.5(2.3–5.3) vs. 2.5(2.0–4.5) days; P = 0.003, adjusted estimate = −0.34, 95% CI: −0.92 to −0.14], and higher safety culture score (149.40 ± 11.74 vs. 153.37 ± 9.74; P = 0.002). …”

DataSheet_1_Biomarkers predicting clinical outcomes in nasopharyngeal cancer patients receiving immune checkpoint inhibitors: A systematic review and meta-analysis.docx by Xiaoyan Qian (1572298)

“…Patients with lower plasma EBV DNA level at baseline obtained a significant benefit on PFS than those with higher plasma EBV DNA level (HR = 0.52, 95% CI: 0.42-0.63, P < 0.001). …”

DataSheet_2_Biomarkers predicting clinical outcomes in nasopharyngeal cancer patients receiving immune checkpoint inhibitors: A systematic review and meta-analysis.pdf by Xiaoyan Qian (1572298)

“…Patients with lower plasma EBV DNA level at baseline obtained a significant benefit on PFS than those with higher plasma EBV DNA level (HR = 0.52, 95% CI: 0.42-0.63, P < 0.001). …”

Table 1_Evaluating biomass and carbon stock responses to thinning and pruning in mature Larix principis-rupprechtii Mayr stands: a case study from Northern China.docx by Jamshid Ali (20981393)