Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

Subjects:

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

Subjects:

GASP mutants initially reach a high population density and subsequently decrease population viability. by Felix J. H. Hol (475373)

Decrease in GABA_B expression in APP mice. by Ksenia V. Kastanenka (3692380)

Heart specific RNase Z variants show a mild decrease in longevity and locomotor response. by Ekaterina Migunova (15909887)

SIINFEKL-specific CD8⁺ T cells treated with anti-CXCR3 decreased the polyfunctionality. by Camila Pontes Ferreira (6194006)

5-FU induces a decrease in the total cell number in cultures of smooth muscle cells. by Marcelo de Carvalho Filgueiras (408321)

“…We found an initial reduction of 20% at 0.01 mM up to a reduction of 70% in 10 mM of 5-FU. …”

Decrease in cleavage score by randomly permuting string-of-beads vaccines. by Emilio Dorigatti (9558024)

“…<p>(a) For each vaccine in the Pareto frontier of each bootstrap, we created 50 new string-of-beads by randomly permuting its epitopes and compared the cleavage scores of the two vaccines. …”

Exogenous FGF4 decreases osteogenic differentiation of mESCs. by Sung-Ho Kook (445098)

h-GAAP Decreases Cell Susceptibility to Extrinsic Apoptosis Pathways by Caroline Gubser (24818)

Damsin (D) and ambrosin (A) treatment decreases the CSC population. by Wendy Soria Sotillo (4408105)

Ageing results in an abrupt decrease in overall neurogenesis in the mouse DG. by Joana Gil-Mohapel (462002)

“…Arrow in (E) indicates a BrdU/NeuN double-labeled cell in the DG of a 9 month-old mouse. …”

CDDO-Me radioprotection decreases with progressive oncogenic manipulations in HBECs and in a matched NSCLC line. by Mariam El-Ashmawy (678638)

“…(F) Increasing concentrations to 50 nM still enhances clonogenic survival of HBEC 30KT, but actually seems to decrease survival in HCC 4017 after 3 Gy radiation. …”

2-APB decreased the expression of maturation markers in human DC. by Romain Félix (586765)

Viability of microencapsulated FP ICCs decreased with time post-transplantation. by Vijayaganapathy Vaithilingam (390354)

“…B) Viability decreased with time post-transplantation. Values are mean ± SEM (n = 100 microcapsules/mice for each time point); *p&lt;0.05 viability for days 7 to 21 when compared to pre-transplantation control and days 1 and 3 post-transplantation; #p&lt;0.05 viability for days 14 and 21 when compared to day 7 post-transplantation (one-way ANOVA with post-hoc Tukey-Kramer Multiple-Comparison test).…”

Glutamate excitotoxicity decreases viability of cultured hippocampal GABAergic neurons. by Márcio S. Baptista (365618)

rAd-p53 induces apoptosis in HCC cell lines with increased Fbxw7 and decreased c-Myc and Cyclin E. by Kangsheng Tu (428934)

“…<p>A) MTT activity was measured after infecting Hep3B cells with rAd-p53 in an MOI gradient to determine their IC₅₀ after 48 h. …”

<i>roh</i> mutation results in Rh1 decrease. by Yu Huang (15093)

“…Scale bar, 50 μm. (B) Western blotting showing decreased Rh1 levels in the <i>roh</i>^{<i>EY04039</i>} mutant (<i>ey-flp Rh1</i>::<i>GFP; FRT42D roh</i>^{<i>EY04039</i>}<i>/ FRT42D GMR-hid CL</i>); the INAD and TRP levels are not affected compared to the wild-type. …”

Loss of HER3 expression decreases the sensitivity to elisidepsin treatment. by Cristina Teixidó (105298)

TNFα significantly decreases PRLR immunoreactivity in the outer root sheath of hair follicles. by Ewan A. Langan (405804)

“…<p>(A) PRLR IR in the outer root sheath of control hair follicles (black arrows) was reduced in comparison PRLR IR after treatment with TNFα at concentrations of (B) 0.5 ng/ml and (C) 5 ng/ml. …”