Novel Allosteric Inhibitors of Deoxyhypusine Synthase against Malignant Melanoma: Design, Synthesis, and Biological Evaluation by Kai-li Liu (11378101)

“…Furthermore, by western blot analysis, compound <b>8m</b> effectively activated caspase 3 and decreased the expressions of GP-100, tyrosinase, eIF5A2, MMP2, and MMP9. …”

TPX2 is constitutively associated with chromatin and impacts the DAPI staining pattern and H4K16ac levels. by Gernot Neumayer (77179)

“…(E) Quantification of H3K9ac and H3K56ac levels from MCF7 cells transfected with control or TPX2 siRNA (n = 4 independent experiments each; p(<i>t</i> test)>0.05; NS: non significant; Error bars represent SE). …”

Temporal and spatial variation of potassium balance in agricultural land at national and regional levels in China by Yingxia Liu (792213)

“…<div><p>Linking potassium (K) balance to soil fertility creates a valuable indicator for sustainability assessment in agricultural land-use systems. …”

Activation of the AMPK/mTOR signaling pathway correlates with curcumin-activated autophagy to restore D-gal-induced tight junction damage in SCs. by Chen Xue (699418)

Hemodynamic parameters. by Paulina Kania-Olejnik (19797617)

“…Anteroposterior diameter increased from 36.5±5.0mm to 38.4±5.5mm (<i>p</i> = 0.05). TA contraction decreased from 7±2% in SR to 2±1% in AF (p = 0.001). …”

Tricuspid annular dimensions. by Paulina Kania-Olejnik (19797617)

“…Anteroposterior diameter increased from 36.5±5.0mm to 38.4±5.5mm (<i>p</i> = 0.05). TA contraction decreased from 7±2% in SR to 2±1% in AF (p = 0.001). …”

Regional tricuspid annular perimeter. by Paulina Kania-Olejnik (19797617)

“…Anteroposterior diameter increased from 36.5±5.0mm to 38.4±5.5mm (<i>p</i> = 0.05). TA contraction decreased from 7±2% in SR to 2±1% in AF (p = 0.001). …”

DataSheet_1_Spliceostatin C, a component of a microbial bioherbicide, is a potent phytotoxin that inhibits the spliceosome.docx by Joanna Bajsa-Hirschel (3902302)

“…SPC inhibited the growth of Arabidopsis thaliana seedlings with an IC50 value of 2.2 µM. The seedlings exposed to SPC displayed a significant response with decreased root length and number and inhibition of gravitropism. …”

Summary of IHC staining of human and mouse tissues. by Soo Jung Lee (8313594)

“…Color codes and letters represent cases of non-conservation between cell types or species that are as follows: purple highlights show proteins expressed in VSMC but not in non-vascular SMC of the same organ in humans only; green highlights show proteins with clearcut differences in cellular staining between human and mouse tissues; blue highlights show proteins that exhibit differences in cardiomyoctes between human and mouse tissues; and red highlights show proteins that exhibited heterogeneity in cardiomyocytes. a: decreased in brain (vs. peripheral) VSMC, b: increased in brain (vs. peripheral) VSMC, c: heterogeneous in VSMC, d: heterogeneous in non-vascular SMC, e: weak, equivocal. …”

Effect of OP2113 on infarct size. by Dominique Detaille (3768979)

Detection of <i>EGFR</i>-mutant CTC and treatment outcome in patients with NSCLC harboring <i>EGFR</i> DelEx19 mutation. by Frank Breitenbuecher (511627)

Recursive sites aid in efficient splicing of long <i>Drosophila</i> introns. by Athma A. Pai (119315)

“…<b>(E)</b> Distribution of the highest maximum entropy score for an internal 5' splice site motif (<i>x-axis</i>) for initial recursive segments (not expected to contain an RS-exon; <i>yellow</i>); non-first recursive segments (potentially contain RS-exons; <i>gold</i>), and non-recursive introns matched for intron length (<i>grey</i>). …”

Effects of functionalized multi-walled carbon nanotubes on toxicity and bioaccumulation of lead in <i>Daphnia magna</i> by Min-Hee Jang (827908)

“…The negatively charged C-MWCNT showed a notable decrease in lead toxicity (LC₅₀ value increased from 0.15 mg L^-1 to 1.08 mg L^-1 in the presence of 10 mg L^-1 C-MWCNT), whereas the positively charged N-MWCNT had only a slight effect on lead toxicity (LC₅₀ value increased from 0.15 mg L^-1 to 0.16 mg L^-1 in the presence of 10 mg L^-1 N-MWCNT). …”

Specific effects of OP2113 on ROS/H₂O₂ production at different sites in isolated rat heart mitochondria. by Dominique Detaille (3768979)

Representative images. by Allan R. Martin (3772705)

The lack of an effect of OP2113 on mitochondrial oxidative phosphorylation. by Dominique Detaille (3768979)

TGF-β signaling modulates miR-181a/b action in the assembly of retinal circuitry. by Sabrina Carrella (404731)

“…Treatment of control-MOs embryos with 80μM SB432542 (m) phenocopied the miR-181a/b-morphant optic nerve length decrease (l). Addition of TGF-β for 24 h (from St30 to St32) to miR-181a/b morphants (n) was sufficient to rescue correct optic nerve growth in Ath5:eGFP morphant embryos. …”

OP2113 improves the recovery of the contractile performance of Langendorff-perfused rat heart during the reperfusion phase following ischemia. by Dominique Detaille (3768979)

Table9_SNX20AR/MiRNA-301a-3p/SNX20 Axis Associated With Cell Proliferation and Immune Infiltration in Lung Adenocarcinoma.xlsx by Yixiao Yuan (11447560)

Table8_SNX20AR/MiRNA-301a-3p/SNX20 Axis Associated With Cell Proliferation and Immune Infiltration in Lung Adenocarcinoma.xlsx by Yixiao Yuan (11447560)