Table_2_DNMT3A R882 Mutations Confer Unique Clinicopathologic Features in MDS Including a High Risk of AML Transformation.docx by Majd Jawad (12157533)

“…By data mining with publicly accessible cancer genomics databases and a clinical genomic database from a tertiary medical institution, DNMT3A R882 mutations were found to be enriched in AML (53% of all DNMT3A mutations) but decreased in frequency in clonal hematopoiesis of indeterminate potential (CHIP) (10.6%) or other myeloid neoplasms including MDS (27%) (p<.001). …”

Table_1_DNMT3A R882 Mutations Confer Unique Clinicopathologic Features in MDS Including a High Risk of AML Transformation.docx by Majd Jawad (12157533)

“…By data mining with publicly accessible cancer genomics databases and a clinical genomic database from a tertiary medical institution, DNMT3A R882 mutations were found to be enriched in AML (53% of all DNMT3A mutations) but decreased in frequency in clonal hematopoiesis of indeterminate potential (CHIP) (10.6%) or other myeloid neoplasms including MDS (27%) (p<.001). …”

Inhibition of Acetyl-CoA Carboxylase 1 (ACC1) and 2 (ACC2) Reduces Proliferation and <i>De Novo</i> Lipogenesis of EGFRvIII Human Glioblastoma Cells by Jessica E. C. Jones (541168)

DataSheet1_Calmodulin mutations affecting Gly114 impair binding to the NaV1.5 IQ-domain.docx by Malene Brohus (840080)

“…A non-arrhythmogenic I10T variant in CaM did not impair Na_V1.5 IQ binding. …”

Depletion of SAMHD1 leads to increased DNA damage. by Kiwon Park (6492266)

S1 Data - by Mariana Paschoalini (8748660)

Inflammatory markers in serum from SHR and SHR-CRP transgenic rats treated with placebo or with salsalate. by Jaroslava Trnovská (715998)

Tet2 and Tet3 function upstream of the Notch and Wnt pathways during RGC differentiation and morphogenesis. by Pawat Seritrakul (4445662)

“…(I-L) Wnt signaling was upregulated by exposing wild-type embryos from 24hpf to 72hpf with 2μM BIO, a GSK3β inhibitor. (I,J) BIO-treated wild-type embryos showed reduced lamination, (K) a decreased percentage of <i>isl2b</i>:GFP⁺ RGCs per retina, and (L) decreased optic nerve diameter relative to DMSO-treated controls, (p = 0.00236 and p<0.0001). …”

Identification of druggable small molecule antagonists of the <i>Plasmodium falciparum</i> hexose transporter PfHT and assessment of ligand access to the glucose permeation pathway... by Monique R. Heitmeier (6686069)

“…WU-1 showed comparable potency in blocking 2-DG uptake in freed parasites and inhibiting parasite growth, with an IC₅₀ of 6.1 ± 0.8 μM and EC₅₀ of 5.5 ± 0.6 μM, respectively. …”

Supplementary Material for: Ectopic ACTH-dependent Cushing’s syndrome Emerging at a Late Stage of a Mixed Histology Neuroendocrine Neoplasm: a case report by Meyers M. (19672471)

“…Laboratory investigations revealed severe hypokalemia (2.3 mmol/L), elevated serum cortisol (1726 nmol/L) and ACTH (194 ng/L) levels. Urinary free cortisol (UFC) measurement was 21-fold the upper limit of the reference range (3614.0 nmol/24h), and cortisol concentration did not decreases after 1mg-dexamethasone suppression test (1812 nmol/L for an expected value < 50 nmol/L), confirming the ACTH-dependent Cushing's syndrome (CS). …”

The BBB neocentromere contains a major and a minor centromere chromatin domain by Alicia Alonso (45373)

“…The adjacent megabase on either side of the central region, shown at a 10 fold reduced scale, was covered by PCR fragments at decreasing density. …”

DataSheet1_Chemical composition, sources and evolution of wintertime inorganic and organic aerosols in urban Shanghai, China.docx by Yijie Qian (15431963)

“…Herein, we present the characterization of non-refractory submicron aerosol (NR-PM₁) in urban Shanghai during winter 2017 by applying an Aerosol Chemical Speciation Monitor (ACSM, Aerodyne Research Inc.). …”

DataSheet_1_microRNA-145-5p inhibits prostate cancer bone metastatic by modulating the epithelial-mesenchymal transition.csv by Bingfeng Luo (13718917)

“…</p>Results<p>Levels of miRNA-145-5p were decreased in Pca bone metastases and miRNA-145-5p inhibited cell proliferation, migration and invasion. miRNA-145-5p inhibited the expression of basic fibroblast growth factor (bFGF), insulin-like growth factor (IGF) and transforming growth factor-β (TGF-β) in PC3 cells. miR-145-5p increased the expression of the epithelial marker E-cadherin and reduced the expression of matrix metalloproteinase 2 and 9 (MMP-2 and MMP-9). …”

Table_1_microRNA-145-5p inhibits prostate cancer bone metastatic by modulating the epithelial-mesenchymal transition.xlsx by Bingfeng Luo (13718917)

“…</p>Results<p>Levels of miRNA-145-5p were decreased in Pca bone metastases and miRNA-145-5p inhibited cell proliferation, migration and invasion. miRNA-145-5p inhibited the expression of basic fibroblast growth factor (bFGF), insulin-like growth factor (IGF) and transforming growth factor-β (TGF-β) in PC3 cells. miR-145-5p increased the expression of the epithelial marker E-cadherin and reduced the expression of matrix metalloproteinase 2 and 9 (MMP-2 and MMP-9). …”

<b>L-Tryptophan as a Frontier in Diabetes Management: A Pilot Study</b> by dr.gayathri M rao (22045067)

“…On 11th day after sacrifice, Intestinal absorption of glucose, Pancreatic and intestinal Na+-K+ ATPase (NKA) activity, intestinal Nitric Oxide (NO), Blood & pancreatic Glucagon like peptide-1(GLP-1), serum total protein, urea and cholesterol, liver and pancreatic histology were studied.</p><p dir="ltr">A significant decrease in the glucose absorption and blood glucose level in the tryptophan treated diabetic group in comparison with diabetic controls. …”

Image_1_Distinct sociodemographic differences in incidence and survival rates for human papillomavirus (HPV)-like, non-HPV-like, and “other”-like oral cavity and pharynx cancers: A... by Kelsey H. Jordan (12316121)

“…Purpose<p>Oral cavity and pharynx cancer (OCPC) cases are traditionally dichotomized into human papillomavirus (HPV) and non-HPV types. Using a proxy for HPV status, the objective was to evaluate differences in incidence and survival rates of OCPC anatomic sub-sites identified as: 1) HPV-like; 2) non-HPV-like (i.e., tobacco/alcohol-related); and 3) “other”-like (i.e., not predominantly HPV-like nor tobacco/alcohol-like) OCPCs.…”

Image_1_Distinct sociodemographic differences in incidence and survival rates for human papillomavirus (HPV)-like, non-HPV-like, and “other”-like oral cavity and pharynx cancers: A... by Kelsey H. Jordan (12316121)

“…Purpose<p>Oral cavity and pharynx cancer (OCPC) cases are traditionally dichotomized into human papillomavirus (HPV) and non-HPV types. Using a proxy for HPV status, the objective was to evaluate differences in incidence and survival rates of OCPC anatomic sub-sites identified as: 1) HPV-like; 2) non-HPV-like (i.e., tobacco/alcohol-related); and 3) “other”-like (i.e., not predominantly HPV-like nor tobacco/alcohol-like) OCPCs.…”

Diseases or functions annotation of thyroid and plasma using IPA. by Malin Larsson (1616557)

Data_Sheet_1_Risk factors associated with the prevalence of Shiga-toxin-producing Escherichia coli in manured soils on certified organic farms in four regions of the USA.pdf by Alda F. A. Pires (5464475)

“…Untreated manure (cattle, horse, and poultry), soil, and irrigation water samples were collected and enrichment cultured for non-O157 STEC. Mixed effects logistic regression models were used to analyze the predictors of non-O157 STEC in the soil up to 180 days post-manure application.…”

Gaussian statistics for buried fragments: The thermal exponent and the Kuhn length. by Stefano Zamuner (715494)