Macroeconomic burden of NMHs for the whole South American region over the period 2020–2050 across various scenarios. by Maddalena Ferranna (9969446)

“…<i>Larger treatment cost impact scenario</i> = treatment costs reduce physical capital investments by a proportion 50% greater than the saving rate; all other assumptions as in the baseline scenario. …”

Reduction of branchiovisceral motor neurons in rhombomere 7 of the Nkx2.2; Nkx2.9 double-null mutant mouse embryo. by Wassan Jarrar (731261)

“…Scale bar in E represents 50 μm and applies to all figure panels.</p>…”

Dys regulates <i>rpr</i> expression and apoptosis. by Sergio Córdoba (645937)

“…Asterisk marks the tip of the leg where endogenous high levels of DCas-3 are observed. (E–F) Close sagittal view of one tarsal joint in a wild type (E) and <i>dys²/dys³</i> mutant prepupal legs where the domains of <i>E(spl)mβ-CD2</i> (red) and the “fold” domain (between the two <i>E(spl)mβ-CD2</i>) are visible. …”

Lead Optimization of Androgen Receptor-HSP27 Disrupting Agents in Glioblastoma by Yaxin Li (312731)

“…Compounds <b>4</b> and <b>6</b> exhibit IC₅₀s of 35 and 23 nM, respectively, to inhibit cell proliferation and also show significant activity to decrease the tumor growth <i>in vivo</i>.…”

Image_1_Extracellular Vesicles Carry lncRNA SNHG16 to Promote Metastasis of Breast Cancer Cells via the miR-892b/PPAPDC1A Axis.TIFF by Wenfei Xia (5055482)

High blood glucose levels in rats after exposure to STZ. by Shatw Khalid Ali (13020885)

Depletion of TPX2 causes defects in 53BP1 ionizing radiation-induced foci formation. by Gernot Neumayer (77179)

“…<p>(A) The protein level of 53BP1 is not affected by miRNA-mediated depletion of TPX2. …”

The effects of metformin, donepezil, insulin glargine, and glibenclamide on brain biomarkers: Amyloid β 42, nitric oxide, acetylcholinesterase, malondialdehyde, β secretase, and pM... by Shatw Khalid Ali (13020885)

Management of Recurrent Bronchopleural Fistula: A Multidisciplinary Approach for A Reconstructive Challenge by Karishma Chandarana (4607131)

“…<p> </p> <p>Urgent pneumonectomy for benign disease is rare but highly morbid, with a perioperative mortality approaching 50 percent. …”

Sample means, SDs, and selected correlations. by Erik Lykke Mortensen (7239170)

“…Educational attainment was a particularly strong predictor of status attainment. …”

A trial of seven footfalls in which the subject (emu) underwent a gradual deceleration. by P. J. Bishop (4219759)

Validation of NUMB as a target for <i>miR-146a</i>. by Pei-Shi Hung (489732)

Novel Antagonist of the Type 2 Lysophosphatidic Acid Receptor (LPA₂), UCM-14216, Ameliorates Spinal Cord Injury in Mice by Nora Khiar-Fernández (8130210)

“…Toward validating this receptor as a target in SCI, we have developed a new series of LPA₂ antagonists, among which compound <b>54</b> (UCM-14216) stands out as a potent and selective LPA₂ receptor antagonist (<i>E</i>_max = 90%, IC₅₀ = 1.9 μM, <i>K</i>_D = 1.3 nM; inactive at LPA_1,3–6 receptors). …”

Novel Antagonist of the Type 2 Lysophosphatidic Acid Receptor (LPA₂), UCM-14216, Ameliorates Spinal Cord Injury in Mice by Nora Khiar-Fernández (8130210)

“…Toward validating this receptor as a target in SCI, we have developed a new series of LPA₂ antagonists, among which compound <b>54</b> (UCM-14216) stands out as a potent and selective LPA₂ receptor antagonist (<i>E</i>_max = 90%, IC₅₀ = 1.9 μM, <i>K</i>_D = 1.3 nM; inactive at LPA_1,3–6 receptors). …”

Image_1_The P2X7 Receptor 489C>T Gain of Function Polymorphism Favors HHV-6A Infection and Associates With Female Idiopathic Infertility.tif by Anna Pegoraro (8213589)

“…We show that functional P2X7R increases while its blockade decreases viral load. …”

Synthesis and Biological Evaluation of Peripheral 5HT_2B Antagonists for Liver Fibrosis by Jihyeon Yoon (8705706)

“…<b>19c</b> markedly reduced fibrotic deposition, with a decrease in fibrosis stage and area in the CCl₄-induced liver fibrosis mouse model. …”

Synthesis and Biological Evaluation of Peripheral 5HT_2B Antagonists for Liver Fibrosis by Jihyeon Yoon (8705706)

“…<b>19c</b> markedly reduced fibrotic deposition, with a decrease in fibrosis stage and area in the CCl₄-induced liver fibrosis mouse model. …”

NADPH oxidation and H₂O₂ production by Bs3 and Bs3_S211A. by Christina Krönauer (11301989)

“…NADPH oxidation was monitored via decrease of absorbance at 340 nm. Yucasin and methimazole (MMI) were dissolved in DMSO and added at a final concentration of 50 μM. …”

The effect of glibenclamide on channel activity at +20, 0 and -20 mV. by Sajjad Salari (736104)

“…Histogram bars show current amplitudes and P_o of reconstituted channels in absence or presence of glibenclamide. The addition of 50 μM glibenclamide resulted in a decreased current jump amplitude and a reduction in P_o. 100 μM glibenclamide caused a total channel inhibition at +20 and 0 mV (n = 5), but was ineffective at -20 mV. …”

Image_3_DNMT3A R882 Mutations Confer Unique Clinicopathologic Features in MDS Including a High Risk of AML Transformation.tif by Majd Jawad (12157533)

“…By data mining with publicly accessible cancer genomics databases and a clinical genomic database from a tertiary medical institution, DNMT3A R882 mutations were found to be enriched in AML (53% of all DNMT3A mutations) but decreased in frequency in clonal hematopoiesis of indeterminate potential (CHIP) (10.6%) or other myeloid neoplasms including MDS (27%) (p<.001). …”