Effect of forskolin (FSK) on cAMP (A) and cGMP (B) concentrations in <i>C. elegans</i>. by Ulrike Beckert (450918)

“…<p>3-day-old, adult animals were incubated with 50 µM FSK for the indicated times. After 1 h, 2 h or 4 h, the animals were washed with M9 buffer and processed for HPLC-MS/MS quantitation. …”

The nature of lung histopathology in hamsters after intranasal inoculation with B.1 (614G), B.1.427 and B.1.429 is similar. by Timothy Carroll (3762841)

Distribution of SARS-CoV-2 RNA+ cells in lungs of hamsters after intranasal inoculation with B.1 (614G), B.1.427 and B.1.429 by in-situ hybridization (ISH). by Timothy Carroll (3762841)

Gender and T cell responses. by Annemarie Namuniina (16496648)

“…The rates of cross-reactive T-cell populations in this exploratory Ugandan population appears higher than previous estimates from resource-rich countries like the United States (20–50% reactivity). It is unclear what role, if any, this cross-reactivity played in decreasing COVID-19 related mortality in Uganda and other African countries, but does suggest that a better understanding of global pre-existing immunological cross-reactivity could be an informative data of epidemiological intelligence moving forward.…”

A combination of CPI-613 and chloroquine significantly suppressed tumor growth in an orthotropic metastatic tumor model of CCS. by Yuki Egawa (5349512)

“…Intraperitoneal administration of CPI-613 (25 mg/kg) and chloroquine (50 mg/kg) significantly decreased tumor growth at the injection site compared to control (Student's <i>t</i>-test, <i>P</i> < 0.01 at days 18 and 23). …”

Clade III N-AChR show similar agonist affinities. by Jennifer D. Noonan (14117157)

“…<p>Concentration- response curves were measured to determine if declining maximal response is due to decreasing ligand affinity. Concentration-response curves for clade III N-AChRs for (A) acetylcholine and (B) nicotine. …”

Rates of hospital admission stratified by gender. by Abdallah Y. Naser (4856113)

“…Rates of same-day hospital admission decreased by 13.3% [from 50.55 (95%CI 49.54–51.57) in 1998 to 43.81 (95%CI 43.00–44.63) in 2019 per 100,000 persons]. …”

Supplementary Material for: Comparison of Insulin, Metformin, and Glyburide on Perinatal Complications of Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis by Wang X. (2828795)

“…<b><i>Conclusions:</i></b> This review suggests that metformin can decrease the incidence of perinatal complications, and it should be considered as a generally safe alternative to insulin.…”

Celecoxib activates SIRT1 in a biochemical, <i>in silico</i> and <i>in vitro</i> cell-based assay. by Madhavi Annamanedi (580922)

“…Right - Model showing the interactions of Celecoxib with SIRT1 protein. C. A representative Western blot showing a dose-dependent decrease of Ac-H3K9 levels in presence of celecoxib. * p-value<0.01 compared to Control. …”

The formation of a negative image mediated by anti-Hebbian burst time dependent plasticity reduces signal but not noise correlations. by Benjamin Simmonds (682287)

“…<p><b>A</b>) One cycle of the 4 Hz sinusoidal stimulus (top, red trace) and synaptic weights (bottom, blue traces) as a function of time for (black traces from top to bottom), t = 0, t = 0.5 sec, t = 1 sec, t = 1.5 sec, t = 2 sec, t = 2.5 sec, t = 3 sec, t = 3.5 sec, t = 4 sec, t = 4.5 sec, t = 5 sec, t = 5.5 sec. …”

Table_1_Relationship Between Dairy Products Intake and Risk of Endometriosis: A Systematic Review and Dose-Response Meta-Analysis.docx by Xiangying Qi (9989599)

“…<p>Objective: Diet lifestyle can influence the risk of endometriosis. Therefore, we conducted a systematic meta-analysis to investigate the association between dairy products and the risk of endometriosis. …”

S6 Fig - by Abishek Balakumar (20189865)

Are Environmental Levels of Nonsteroidal Anti-Inflammatory Drugs a Reason for Concern? Chronic Life-Cycle Effects of Naproxen in Zebrafish by Susana Barros (586042)

“…The nonsteroidal anti-inflammatory drug naproxen (NPX) is among the most consumed pharmaceuticals worldwide, being detected in surface waters within the ng to μg/L range. Considering the limited chronic ecotoxicity data available for NPX in aquatic ecosystems, the present study aimed at evaluating its impact in the model organism Danio rerio, following a full life-cycle exposure to environmentally relevant concentrations (0.1 to 5.0 μg/L). …”

Dual action of novel 5-nitroguaiacol-based hydrazones: Targeting aldolase-a and inducing apoptosis in lung cancer by Mürvet Tümenci (22474400)

“…Compounds <b>3d</b> and <b>3k</b> exhibited selective and potent cytotoxicity (IC₅₀ = 10.24 µM and 4.99 µM, respectively) and strong aldolase A (ALDOA) inhibition at 10 µM (89.89% and 75.19%). …”

Study of <i>n</i>-Butylcyclohexane/Air Ignition over a Broad Range of Temperatures in Shock Tube by Dexiang Zhang (3554777)

“…<p>Measurements of ignition delay times for <i>n</i>-butylcyclohexane/air were performed over temperatures of 707–1458 K, pressures of 2.0, 5.0, and 15.0 atm, and equivalence ratios of 0.5, 1.0, and 2.0 in a heated shock tube. …”

In vivo analysis of the δ-GABA_A-Rs in the cerebellar granule layer in WT and TTR-/- mice. by Li Zhou (54356)

“…The total δ protein level showed no difference, while the biotinylated surface δ protein level decreased significantly in TTR-/- mice. Both total and the surface γ2 GABA_A-Rs have no difference between WT and TTR-/- mice. …”

Sexual function after total laparoscopic hysterectomy or transabdominal hysterectomy for benign uterine disorders: a retrospective cohort by Yiqun Wang (2804704)

“…Both TLH and TAH had comparable negative effects on sexual function in women treated for benign uterine tumors in China, with a decreased frequency of sexual activity, reduced libido, orgasm dysfunction, and increased dyspareunia.…”

Constant temperature effects on germination percent data were analyzed using a segmented regression (a) and germination rate data were analyzed using linear regression (b) for 6 po... by Michael C. Beall (18764654)

DFMG attenuates angiogenesis induced by oxidative stress injury in endothelial cells. by Pingjuan Bai (18404486)

PAR1 or PAR4 activation reduces urothelial MIF in mouse bladder. by Dimitrios E. Kouzoukas (746678)

“…White arrows point to intraluminal surface of the urothelia. MIF immunofluorescent labeling localized to urothelium (<b>A, D</b>) and a decrease in urothelial MIF immunofluorescence was observed after PAR1-AP (<b>B</b>) or PAR-4-AP (<b>E</b>) treatment when compared to control peptide-treated groups (<b>A</b>, <b>D</b>). …”