Image_2_Experimental evidence of the genetic hypothesis on the etiology of bicuspid aortic valve aortopathy in the hamster model.TIF by María Teresa Soto-Navarrete (3202896)

“…<p>Bicuspid aortopathy occurs in approximately 50% of patients with bicuspid aortic valve (BAV), the most prevalent congenital cardiac malformation. …”

Image 2_Proteome changes during in vitro culture adaptation of Toxoplasma gondii archetypal II and III field isolates.tif by Joachim Müller (265589)

“…Few reports exist on the molecular bases that govern this adaptation. Herein, we analyzed the T. gondii proteomes of different isolates at two timepoints during cell culture adaptation.…”

Table2_Data-driven analysis to identify prognostic immune-related biomarkers in BRAF mutated cutaneous melanoma microenvironment.DOC by Biao Huang (215504)

“…<p>Skin cutaneous melanoma is one of the deadly diseases, and more than 50% of the patients have BRAF gene mutations. Evidence suggests that oncogenic BRAF modulates the immune system’s ability to recognize SKCM cells. …”

Data_Sheet_1_Study on the effect and mechanism of Lacticaseibacillus rhamnosus AFY06 on inflammation-associated colorectal cancer induced by AOM/DSS in mice.ZIP by Jing Zhang (23775)

“…</p>Results<p>LR-AFY06 treatment alleviated weight loss, increased organ index, reduced intestinal tumor incidence, improved histopathological damage, decreased the levels of inflammatory cytokines such as interleukin-6 (IL-6), interleukin-1 beta (IL-1β), tumor necrosis factor alpha (TNF-α), nuclear factor κB (NF-κB), and inducible nitric oxide synthase (iNOS) in the serum and colon tissue, downregulated the mRNA expression of inhibitor of NF-κB beta (IκBβ), p65, p50, p52, B-cell lymphoma-2 (Bcl-2), and B-cell lymphoma-extra large (Bcl-xL) in colon tissues, and increased the mRNA expression of Bid and caspase-8. …”

Image_6_Experimental evidence of the genetic hypothesis on the etiology of bicuspid aortic valve aortopathy in the hamster model.TIF by María Teresa Soto-Navarrete (3202896)

“…<p>Bicuspid aortopathy occurs in approximately 50% of patients with bicuspid aortic valve (BAV), the most prevalent congenital cardiac malformation. …”

Image_4_Experimental evidence of the genetic hypothesis on the etiology of bicuspid aortic valve aortopathy in the hamster model.TIF by María Teresa Soto-Navarrete (3202896)

“…<p>Bicuspid aortopathy occurs in approximately 50% of patients with bicuspid aortic valve (BAV), the most prevalent congenital cardiac malformation. …”

Image 6_Proteome changes during in vitro culture adaptation of Toxoplasma gondii archetypal II and III field isolates.tif by Joachim Müller (265589)

“…Few reports exist on the molecular bases that govern this adaptation. Herein, we analyzed the T. gondii proteomes of different isolates at two timepoints during cell culture adaptation.…”

Supplementary Material for: Clinical and brain MRI characteristics of patients with Anti-N-Methyl-D-Aspartate Receptor Encephalitis: A 10-Year Retrospective Study by figshare admin karger (2628495)

“…Although 91% of patients with mRS >2 before treatment, statistically significant decreased mRS were observed after treatment (mRS: 3.50 ± 0.94 vs mRS: 1.91 ± 1.53, P < 0.001). …”

Image_8_Experimental evidence of the genetic hypothesis on the etiology of bicuspid aortic valve aortopathy in the hamster model.TIF by María Teresa Soto-Navarrete (3202896)

“…<p>Bicuspid aortopathy occurs in approximately 50% of patients with bicuspid aortic valve (BAV), the most prevalent congenital cardiac malformation. …”

Data_Sheet_1_A Label-Free Quantitative Proteomic Analysis of Mouse Neutrophil Extracellular Trap Formation Induced by Streptococcus suis or Phorbol Myristate Acetate (PMA).XLS by Xiaoping Wang (110673)

“…Of these peptidases, MMP-8 expression was obviously decreased in response to PMA, but it was not significantly changed in response to S. suis. …”

Image_7_Experimental evidence of the genetic hypothesis on the etiology of bicuspid aortic valve aortopathy in the hamster model.TIF by María Teresa Soto-Navarrete (3202896)

“…<p>Bicuspid aortopathy occurs in approximately 50% of patients with bicuspid aortic valve (BAV), the most prevalent congenital cardiac malformation. …”

Data_Sheet_1_Activity-State Dependent Reversal of Ketamine-Induced Resting State EEG Effects by Clozapine and Naltrexone in the Freely Moving Rat.docx by Christien Bowman (12007985)

“…Naltrexone inhibited frequencies above 50 Hz and significantly reduced the ketamine-induced increase in high frequency oscillations. …”

Image_2_Positive Effects of Neutrophil Elastase Inhibitor (Sivelestat) on Gut Microbiome and Metabolite Profiles of Septic Rats.tif by Yali Sun (2099593)

“…</p>Results<p>Sivelestat administration significantly improved the survival of septic rats (80% vs 50%, P = 0.047). Microbiome analysis showed that the microbiota composition of rats in the CLP group was significantly disturbed, as potential pathogens such as Escherichia-Shigella and Gammaproteobacteria became dominant, and the beneficial microbiota represented by Lactobacillus decreased. …”

<i>CDKN3</i> mRNA as a Biomarker for Survival and Therapeutic Target in Cervical Cancer by Eira Valeria Barrón (796117)

“…<div><p>The cyclin-dependent kinase inhibitor 3 (<i>CDKN3</i>) gene, involved in mitosis, is upregulated in cervical cancer (CC). We investigated <i>CDKN3</i> mRNA as a survival biomarker and potential therapeutic target for CC. …”

Data Sheet 2_Assessing the evolution of infectious disease preparedness among a province with poor economy in China in the wake of COVID-19.docx by Huaying Liu (8312517)

“…</p>Methods<p>Utilizing random sampling, we conducted questionnaire surveys among primary care physicians from Guangxis primary medical institutions in June 2019 and October 2022, and analyzed the data with SPSS software.…”

Image_10_Experimental evidence of the genetic hypothesis on the etiology of bicuspid aortic valve aortopathy in the hamster model.TIF by María Teresa Soto-Navarrete (3202896)

“…<p>Bicuspid aortopathy occurs in approximately 50% of patients with bicuspid aortic valve (BAV), the most prevalent congenital cardiac malformation. …”

A Porphodimethene Chemical Inhibitor of Uroporphyrinogen Decarboxylase by Kenneth W. Yip (257594)

“…Because there is no known chemical UROD inhibitor suitable for use in translational studies, we aimed to design, synthesize, and characterize such a compound. …”

Table_6_Species-specific metabolome changes during salinity downshift in sub-Arctic populations of Mytilus edulis and M. trossulus.docx by Inna M. Sokolova (3857770)

“…Taurine emerged as the dominant osmolyte, comprising over 50% of the total free amino acid pool, with aspartate and glycine contributing 15–30%. …”

Diversity of a wall-associated kinase gene in wild and cultivated barley by Beata I. Czajkowska (466314)

“…To begin to address the latter hypothesis we studied the diversity of <i>HvWAK1</i>, a wall-associated kinase gene involved in root proliferation, in 220 wild barley accessions and 200 domesticated landraces. …”

Image_3_Experimental evidence of the genetic hypothesis on the etiology of bicuspid aortic valve aortopathy in the hamster model.TIF by María Teresa Soto-Navarrete (3202896)

“…<p>Bicuspid aortopathy occurs in approximately 50% of patients with bicuspid aortic valve (BAV), the most prevalent congenital cardiac malformation. …”