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ng decrease » nn decrease (Expand Search), _ decrease (Expand Search), we decrease (Expand Search)
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5 ht » 5 h (Expand Search)
5 ng » 5 mg (Expand Search), 5 g (Expand Search), 5 nm (Expand Search)
ng decrease » nn decrease (Expand Search), _ decrease (Expand Search), we decrease (Expand Search)
ht decrease » _ decrease (Expand Search), nn decrease (Expand Search), we decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
5 ht » 5 h (Expand Search)
5 ng » 5 mg (Expand Search), 5 g (Expand Search), 5 nm (Expand Search)
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The impact of excessive DNA amounts used for bisulfite conversion on the amplification efficiency and the methylation level of <i>LINE-1</i> and <i>Alu</i>.
Published 2024“…The ΔCT values significantly differ at input amounts from 500 ng to 0.5 ng. (<b>D, E</b>) An increase in methylation level of <i>LINE-1</i> (D) and <i>Alu</i> (E) was associated with a decrease in DNA input for bisulfite conversion. …”
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NgR1 KO mice exhibited an increase in excitatory synapses and a decrease in inhibitory synapses, indicating an imbalance of synaptic transmission.
Published 2025“…The inhibitory synaptic density of NgR1 mice showed a significant decrease when compared to WT mice (***P < 0.001). …”
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Image1_The serotonin receptor 5-HT2A modulates lifespan and protein feeding in Drosophila melanogaster.pdf
Published 2022“…Loss of the 5-HT2A receptor extends lifespan and induces a resistance to changes in dietary protein that are normally detrimental to lifespan. 5-HT2A<sup>−/−</sup> null mutant flies also display decreased protein feeding and protein content in the body. …”
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Image2_The serotonin receptor 5-HT2A modulates lifespan and protein feeding in Drosophila melanogaster.pdf
Published 2022“…Loss of the 5-HT2A receptor extends lifespan and induces a resistance to changes in dietary protein that are normally detrimental to lifespan. 5-HT2A<sup>−/−</sup> null mutant flies also display decreased protein feeding and protein content in the body. …”
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Image3_The serotonin receptor 5-HT2A modulates lifespan and protein feeding in Drosophila melanogaster.pdf
Published 2022“…Loss of the 5-HT2A receptor extends lifespan and induces a resistance to changes in dietary protein that are normally detrimental to lifespan. 5-HT2A<sup>−/−</sup> null mutant flies also display decreased protein feeding and protein content in the body. …”
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Video_5_Contribution of 5-HT2 Receptors to the Control of the Spinal Locomotor System in Intact Rats.WMV
Published 2020“…Little is known about the role of 5-HT receptors in the control of voluntary locomotion, so we administered inverse agonists of 5-HT<sub>2</sub> (Cyproheptadine; Cypr), 5-HT<sub>2A</sub> neutral antagonist (Volinanserin; Volin), 5-HT<sub>2C</sub> neutral antagonist (SB 242084), and 5-HT<sub>2B/2C</sub> inverse agonist (SB 206553) receptors intrathecally in intact rats and monitored their effects on unrestrained locomotion. …”
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Structure-Based Design of a Chemical Probe Set for the 5‑HT<sub>5A</sub> Serotonin Receptor
Published 2022“…Docking over 6 million molecules against a 5-HT<sub>5A</sub>R homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT<sub>5A</sub>R with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”
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Structure-Based Design of a Chemical Probe Set for the 5‑HT<sub>5A</sub> Serotonin Receptor
Published 2022“…Docking over 6 million molecules against a 5-HT<sub>5A</sub>R homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT<sub>5A</sub>R with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”
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