A refinement approach in a mouse model of rehabilitation research. Analgesia strategy, reduction approach and infrared thermography in spinal cord injury by Veronica Redaelli (7586621)

“…The aims of this investigation were 1- to assess acute surgical pain in mice subjected to SCI, 2- to compare the efficacy of commonly used analgesia (three buprenorphine subcutaneous injection in 48 hours, 0,15 mg/kg each) with a combination of opioid and NSAID (one subcutaneous injection of 5 mg/kg carprofen before surgery followed by three buprenorphine subcutaneous injection in 48 hours, 0,15 mg/kg each) and 3- to test if Infrared Thermography (IRT) could be a potential new Refinement method to easily assess thermoregulation, an important metabolic parameter. …”

Detoxifying enzyme activities of slug larvae and adults treated with LC₅₀ for 24 and 48 h, respectively. by Haojun Li (11007721)

Protective enzyme activities of slug larvae and adults treated with LC₅₀ for 24 and 48 h, respectively. by Haojun Li (11007721)

A Dietary Supplement Containing Cinnamon, Chromium and Carnosine Decreases Fasting Plasma Glucose and Increases Lean Mass in Overweight or Obese Pre-Diabetic Subjects: A Randomized... by Yuejun Liu (800012)

“…</p><p>Results</p><p>Four-month treatment with the dietary supplement decreased FPG compared to placebo (-0.24±0.50 <i>vs</i> +0.12±0.59 mmol/L, respectively, p = 0.02), without detectable significant changes in HbA1c. …”

Effect of contamination on animal food-contact zone and their types after porcine epidemic diarrhea virus (PEDV) inoculated animal food manufacturing^†. by Loni L. Schumacher (3666775)

Effect of different doses of FA-SnO₂ NPs (50 mg/kg for group B, 100 mg/kg for group C and 200 mg/kg for group D) on biochemical profiling of the tested male Wistar rats... by Demiana H. Hanna (11512956)

Effect of different doses of FA-SnO₂ NPs (50 mg/kg for group B, 100 mg/kg for group C and 200 mg/kg for group D) on hematological parameters of the tested male Wistar ra... by Demiana H. Hanna (11512956)

Diet composition of porcine epidemic diarrhea virus (PEDV) inoculated animal food, as fed basis. by Loni L. Schumacher (3666775)

Layout of research facility. by Loni L. Schumacher (3666775)

IRT measurements. by Veronica Redaelli (7586621)

Pain score based on ear position according to MGS method. by Veronica Redaelli (7586621)

Study design. by Veronica Redaelli (7586621)

A refinement approach in a mouse model of rehabilitation research. Analgesia strategy, reduction approach and infrared thermography in spinal cord injury - Fig 2 by Veronica Redaelli (7586621)

Gene clustering identifies up- and down-regulated groups that control development, pluripotency, and cell division. by Michael Shelton (382572)

“…<p>Pluripotent H9 hESCs were differentiated for 50 days as previously described [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0222946#pone.0222946.ref012" target="_blank">12</a>], beginning with high (7.5 μM or 10 μM) CHIR99021 concentrations. mRNA samples from the indicated time points were subjected to gene expression profiling. …”

<i>M</i>. <i>leprae</i> was detected in the liver of a multibacillary patient and can decrease ApoA-I expression in HepG2 cells. by Robertha Mariana R. Lemes (8635935)

DN Rab1 and Rab8 decrease plasma membrane expression of KCa3.1 in polarized epithelia. by Claudia A. Bertuccio (309866)

Administration of γPGA attenuates Th2 immune responses elicited by the cysteine protease papain through a decrease in basophils. by Hyun Jung Park (116737)

Induction of peripheral neuropathy after long-term exposure to oxaliplatin. by Jin-Hee Park (732531)

“…<p>5% dextrose (Cont) and oxaliplatin (3 mg/kg; Oxal) were administered by i.p. injection for 60 days as shown in the schedule (a). …”

The minimum inhibitory concentrations (µg/mL) and the minimum bactericidal concentrations (µg/mL) of synthesized 1,2,3,5-tetrazine derivatives. by Jean Paul Dzoyem (6424445)

Subjects:

Percentages of inhibition of biofilm formation and eradication of synthesized 1,2,3,5-tetrazine derivatives. by Jean Paul Dzoyem (6424445)

Subjects: