Data_Sheet_1_SUMOylation of Alpha-Synuclein Influences on Alpha-Synuclein Aggregation Induced by Methamphetamine.doc by Lin-nan Zhu (5681939)

“…Levels of the ubiquitin-proteasome system (UPS)-related makers ubiquitin (Ub) and UbE1, as well as the autophagy-lysosome pathway (ALP)-related markers LC3, P62 and lysosomal associated membrane protein 2A (LAMP2A), were also measured in SH-SY5Y cells transfected with lentivirus and mice injected with adenovirus. …”

Image_2_P300/CBP Associated Factor (PCAF) Deficiency Enhances Diet-Induced Atherosclerosis in ApoE3*Leiden Mice via Systemic Inhibition of Regulatory T Cells.JPEG by Alwin de Jong (4012250)

“…Expression of FoxP3 by systemic CD4⁺ T cells decreased 1.8 fold in ApoE3^*LeidenxPCAF^−/− after 5 months HFD and remained significantly reduced after 5 months of HFD. …”

Molecular Characterization of Acquired Tolerance of Tumor Cells to Picropodophyllin (PPP) by Jamileh Hashemi (131207)

“…Using Nexus software analysis we combined the array-CGH data with data from gene expression profilings and identified genes that were altered in both inputs. A subset of genes identified as downregulated (<em>ALDH1A3</em>, <em>ANXA1</em>, <em>TLR4</em> and <em>RAB5A</em>) or upregulated (<em>COX6A1</em>, <em>NFIX</em>, <em>ME1</em>, <em>MAPK</em> and <em>TAP2</em>) were validated by siRNA in the tolerant or parental cells to alter sensitivity to PPP and confirmed to alter sensitivity to PPP in further cell lines.…”

Table_1_Regulation of miRNA expression in the prefrontal cortex by fecal microbiota transplantation in anxiety-like mice.docx by Simin Chen (9549665)

“…MiRNA analysis identified five key miRNAs affecting GAD pathogenesis, including mmu-miR-10a-5p, mmu-miR-1224-5p, mmu-miR-218-5p, mmu-miR-10b-5p, and mmu-miR-488-3p. …”

Image_1_P300/CBP Associated Factor (PCAF) Deficiency Enhances Diet-Induced Atherosclerosis in ApoE3*Leiden Mice via Systemic Inhibition of Regulatory T Cells.JPEG by Alwin de Jong (4012250)

“…Expression of FoxP3 by systemic CD4⁺ T cells decreased 1.8 fold in ApoE3^*LeidenxPCAF^−/− after 5 months HFD and remained significantly reduced after 5 months of HFD. …”

<i>Sphagnum</i> Mosses - Masters of Efficient N-Uptake while Avoiding Intoxication by Christian Fritz (507612)

“…</p><p>We investigated the effects of N-concentration (1, 5, 10, 50, 100, 500 µM), N-form (¹⁵N - ammonium or nitrate) and exposure time (0.5, 2, 72 h) on uptake kinetics for <i>Sphagnum magellanicum</i> from a pristine bog in Patagonia (Argentina) and from a Dutch bog exposed to decades of N-pollution.…”

The STIM2-TM domain activates the cytosolic region of STIMs less efficiently than that of STIM1. by Sisi Zheng (1574473)

“…Left: average time course of whole-cell I_CRAC currents measured at –100 mV. Currents mediated by STIM1121-ΔK developed significantly more slowly than control (time to peak, 72 ± 7 s versus 147 ± 9 s, <i>n</i> = 7, ****<i>P</i> < 0.0001, <i>t</i> test), with the maximal current density also reduced (–5.5 ± 0.8 pA/pF versus –1.5 ± 0.1 pA/pF, <i>n</i> = 7, *****<i>P</i> < 0.0004, <i>t</i> test). …”

DataSheet_1_Sexual reproduction and biometry of the non-zooxanthellate papillose cup coral Paracyathus pulchellus.docx by Chiara Marchini (819726)

“…<p>Basic information on the reproductive biology of many scleractinian corals species is limited or entirely lacking, particularly from temperate zones, though it is essential for a better understanding of their ecology. This study describes the morphological aspects and the annual cycle of gametogenesis and biometric parameterss of the papillose cup coral Paracyathus pulchellus collected at Palinuro (Italy, Southern Tyrrhenian Sea), filling a knowledge gap about the reproductive biology of a widespread Mediterranean and Northern Atlantic coral. …”

SPO11-dependent and -independent RAD51 foci in mouse meiocytes. by Fabrizia Carofiglio (418861)

“…<p>(A–C) The number of RAD51 foci decreases from leptotene to zygotene in <i>Spo11^+/+</i> and <i>Spo11^+/YF</i> spermatocytes, whereas a few foci are detected in <i>Spo11^YF/YF</i> spermatocytes and oocytes at both stages. …”

Data_Sheet_1_Use of magnetic source imaging to assess recovery after severe traumatic brain injury—an MEG pilot study.PDF by Anand Karthik Sarma (17331364)

“…</p>Methods<p>In this study, we explored the feasibility of conducting resting state magnetoencephalography (MEG) in a case series of sTBI patients acutely after injury (~7 days), and then about 1.5 and 8 months after injury. …”

Image1_Ameliorative Effects of Osthole on Experimental Renal Fibrosis in vivo and in vitro by Inhibiting IL-11/ERK1/2 Signaling.pdf by Fan Wu (43375)

Kidneys grown in the low volume glass system show normal responses to known morphogens. by David D. R. Sebinger (364856)

Building Strain with Large Macrocycles and Using It To Tune the Thermal Half-Lives of Hydrazone Photochromes by Quan Li (157017)

“…Strain has been used as a tool to modulate the reactivity (e.g., mechanochemistry) and thermal isomerization kinetics of photochromic compounds. …”

Building Strain with Large Macrocycles and Using It To Tune the Thermal Half-Lives of Hydrazone Photochromes by Quan Li (157017)

“…Strain has been used as a tool to modulate the reactivity (e.g., mechanochemistry) and thermal isomerization kinetics of photochromic compounds. …”

Probing Interaction between ssDNA and Carbon Nanotubes by Raman Scattering and Electron Microscopy by Masayuki Shoda (2380057)

“…We report experimental results of Raman scattering showing that single-stranded DNA (ssDNA) effectively modifies the electronic structure of metallic carbon nanotubes with the diameter of 1.5−1.6 nm but not for the same diameter class of semiconducting tubes. …”

Endothelial density analysis by age group of corneal donors in an eye bank in Paraná State, Brazil by Karla Mulinari Vicini (10371090)

“…In the evaluation from the second to the sixth decade, there was no pattern, sometimes there was an increase, sometimes a decrease in the average endothelial density.</p><p></p>…”

Reduced but functional CD8+ T-cell compartment after fully-mismatched HLA class I thymus transplantation. by Adriana S. Albuquerque (323475)

“…<p>(A) Circulating CD8+ αβ T-cells analysed 58 months post-transplantation (5% of total lymphocytes; 83cells/µl) by flow cytometry in terms of: naïve/memory/effector phenotype assessed by CD45RA and CD27 expression; levels of activation markers (CD38 and HLA-DR); IFN-γ and IL-2 production upon PMA+ionomycin stimulation; <i>ex vivo</i> frequency of cycling cells (Ki-67+); and <i>ex vivo</i> frequency of apoptotic cells assessed by annexin V staining. …”

Nephrin deletion in adult mature glomerulus results in focal segmental glomerulosclerosis and proteinuria. by Rakesh Verma (151646)

“…<p>(A) Mice with tamoxifen-induced nephrin deletion develop proteinuria at 6–8 weeks following tamoxifen. …”

Building Strain with Large Macrocycles and Using It To Tune the Thermal Half-Lives of Hydrazone Photochromes by Quan Li (157017)

“…Strain has been used as a tool to modulate the reactivity (e.g., mechanochemistry) and thermal isomerization kinetics of photochromic compounds. …”

Schematic representation of dsRNA- and virus-induced beta cell apoptosis. by Maikel L. Colli (179059)