Acute leptin treatment in chronically food restricted mice does not significantly affect hypothalamic <i>Pomc</i> or <i>Agrp</i> mRNA between genotypes as demonstrated by qPCR. by Elisa S. Na (4114219)

“…<i>Agrp</i> mRNA is not substantially affected by leptin administration but there is a significant decrease in <i>Agrp</i> mRNA in all groups compared to the WT PBS-treated group. …”

Subthreshold responses are preserved by low-level illumination. by Sarah Jarvis (4925683)

“…<p>(A) The native response of L5PC when driven by presynaptic inputs of a fixed rate. …”

Robust and Porous β‑Diketiminate-Functionalized Metal–Organic Frameworks for Earth-Abundant-Metal-Catalyzed C–H Amination and Hydrogenation by Nathan C. Thacker (1522195)

Combination therapy restores wound neovascularization partially though PC-mediated vasculogenesis. by Robert J. Allen Jr. (540312)

“…<b>C</b>) BrdU-labeling of PCs in the presence of AMD3100 demonstrates only minor, non-significant, inhibition in PC proliferation (15.4±3.3% decrease, p = 0.06). <b>D</b>) When 2.5×10⁴ DiI-labeled PCs were intravascularly delivered to wounded animals on post-wounding day 1 and wounds were then harvested on post-wounding day 28 after lectin perfusion, we observe direct incorporation of PCs (red) into wound neovasculature (green) with DAPI counterstain (blue). …”

Late Quaternary evolution of the southern Brazilian Atlantic coast by Ciro Cerrone (14964274)

“…In particular, the Last Interglacial (LIG; Marine Isotope Stage 5e, ~ 125 ka) is considered a process analogue for understanding the current interglacial because during the LIG higher temperatures than the pre-industrial era led to an increase in the global sea level and decrease in ice sheets volume. …”

Table_1_Methane Reduction Potential of Two Pacific Coast Macroalgae During in vitro Ruminant Fermentation.DOCX by Charles G. Brooke (9133610)

“…At a dose rate of 5% dry matter (DM), California-sourced A. taxiformis and Z. farlowii reduced methane production by up to 74% (p < 0.05) and 11% (p < 0.05) during in vitro rumen fermentation, respectively. …”

Impact at the leaf assimilation level. by José C. Ramalho (493978)

“…For each parameter, the mean values ± SE (n = 5–8) followed by different letters express significant differences between temperature treatments for the same water availability level (a, b, c, d, e, f), or between water treatments for each temperature treatment (A, B, C), always separately for each genotype.…”

7-Valent Pneumococcal Conjugate Vaccination in England and Wales: Is It Still Beneficial Despite High Levels of Serotype Replacement? by Yoon Hong Choi (52781)

“…</p> <h3>Conclusion</h3><p>Our model suggests that PCV7 vaccination could result in a decrease in overall invasive pneumococcal disease, particularly in children, even in an environment of rapid replacement with non-PCV7 serotypes within 5 years of vaccine introduction at high coverage.…”

Plasmonic Bubbles in <i>n</i>‑Alkanes by Mikhail E. Zaytsev (6033155)

“…In this paper, we study the formation of microbubbles upon the irradiation of an array of plasmonic Au nanoparticles with a laser in <i>n</i>-alkanes (C_<i>n</i>H_2<i>n</i>+2, with <i>n</i> = 5–10). …”

Image_1_Breaking All the Rules: The First Recorded Hard Substrate Sessile Benthic Community Far Beneath an Antarctic Ice Shelf.JPEG by Huw J. Griffiths (9468143)

“…<p>The seafloor beneath floating ice shelves accounts roughly a third of the Antarctic’s 5 million km² of continental shelf. …”

Table 1_Evaluation of clopidogrel responsiveness using the Platelet Function Analyzer-200 (PFA-200) in dogs.docx by Joon-Ho Shin (2161726)

“…The reference interval for P2Y CT in healthy dogs was 40.0–141.5 s, with a mean of 63.9 ± 26.82 s. Hypercoagulable dogs showed a mean baseline P2Y CT of 77.4 ± 37.6 s. …”

Inhibiting mTORC2 down-regulated TRPC6 protein expression. by Fangrui Ding (659863)

“…(E, F) In podocytes exposed to ku0063794 for 2, 4, 8, 12, or 24 hours, the TRPC6 protein levels were decreased in a time-dependent manner. (G, H) The TRPC6 protein levels were decreased in a concentration-dependent manner following treatment with 0.5, 1, 2, 3, or 4 µmol/l ku0063794 compared to the control group. …”

HIMF-stimulated HMSC migration is PI-3K-dependent. by Daniel J. Angelini (363843)

“…<p>A: HMSCs (10⁵ cells) were cultured in the upper chamber of a transwell plate; the lower chamber held medium containing BSA (control) or HIMF (100 nM). …”

The Evolution of Carbon Nanotube Network Structure in Unidirectional Nanocomposites Resolved by Quantitative Electron Tomography by Bharath Natarajan (1360506)

“…The CNTs are observed to exhibit a nonlinear increase in bundling and alignment and a decrease in waviness as a function of increasing <i>V</i>_f. …”

Table_2_Early onset age increases the risk of musculoskeletal damage in patients with type 2 diabetes.docx by Biao Zheng (22390)

“…With the prolongation of the course of the disease, the risk of muscle mass and/or bone mineral density decrease in EOT2D increases.</p>Conclusion<p>EOT2D brings a greater risk of sarcopenia and/or osteoporosis, as well as a higher risk of reduced ASM and BMD. …”

I’m alone but not lonely. U-shaped pattern of perceived loneliness during the COVID-19 pandemic in the UK and Greece by Andrea Bizzego (9655259)

“…Subsequent statistical analysis showed a significant U-shaped curve for loneliness levels, with a decrease during the 4th and 5th lockdown weeks. …”

Systemic (S)-roscovitine displays neuroprotective efficacy in an adult mouse model of permanent MCAo. by Bénédicte Menn (243852)

“…Scale bar: A, B: 9.5 mm * p<0.01, <i>t</i>-test.</p>…”

DataSheet_1_Effects of water hyacinth biochar on lettuce growth in cadmium-contaminated soil.docx by Chunhuo Zhou (14072268)

“…Within a certain carbonization time (0.5~2 h) and carbonization temperature (300°C~700°C), the content of available Cd in the soil decreases with the increase of the carbonization temperature and time, which might be the main reason for the lower Cd concentration in lettuce after applying the biochar. …”

Table 1_UVH6 regulates osmotic and heat stress tolerance by modulating transcription.xlsx by Koya Kobayashi (17987995)

“…In Arabidopsis thaliana, UVH6 mutations impair DNA repair, enhance UV sensitivity, and decrease heat stress tolerance. We here isolated acquired osmotolerance–defective12 (aod12) mutant derived from osmotolerant Bu-5 accession; this mutant had pale green leaves and was osmosensitive and heat sensitive. …”

Loss of PLZF Expression in Prostate Cancer by Immunohistochemistry Correlates with Tumor Aggressiveness and Metastasis by Guang-Qian Xiao (711983)

“…Our results demonstrated that PLZF was strongly expressed in almost all (~100%) benign luminal cells (n=77) and low grade (Gleason pattern 3) PCa (n=70) and weak or absent (100%) in basal cells (n=70). Decreased or lost expression of PLZF was evidenced in 26% of high-grade (Gleason 4 and 5) primary PCa (n=70) and 84% metastatic PCa (n=43). …”