Image_1_Osmotic Imbalance, Cytoplasm Acidification and Oxidative Stress Induction Support the High Toxicity of Chloride in Acidophilic Bacteria.PNG by Javier Rivera-Araya (7554596)

“…On the other hand, the intracellular pH significantly decreased from 6.7 to pH 5.5 and oxygen consumption increased significantly when the cells were exposed to NaCl stress. …”

Presentation_2_Integrated Analysis of the Transcriptome and Metabolome Revealed the Molecular Mechanisms Underlying the Enhanced Salt Tolerance of Rice Due to the Application of Ex... by Ziyan Xie (9927878)

“…However, the molecular basis of melatonin-mediated salt tolerance in rice remains unclear. In the present study, we performed an integrated transcriptome and metabolome profiling of rice seedlings treated with salt, melatonin, or salt + melatonin. …”

Genomic driver underlies clonal shift of methicillin-resistant <i>Staphylococcus aureus</i> in the healthcare setting by Shuangshuang Li (441516)

“…We conducted a longitudinal analysis of 3,410 clinical HA-MRSA isolates collected between 2005 and 2020 to assess clonal prevalence and genomic changes. …”

DataSheet1_Effects of modified Danggui Sini Decoction as adjuvant therapy for angina pectoris in coronary heart disease: a systematic review and meta-analysis based on randomised c... by He Wang (250350)

“…The quality of included studies was assessed using the Cochrane Handbook version 5.1, and meta-analysis was executed via RevMan 5.4 software.…”

Supplementary Material for: Antiplatelet Therapy after Intracerebral Hemorrhage and Subsequent Clinical Events: A 12-Year South Korean Cohort Study by Moon J.Y. (10539137)

“…Among 220 patients with a history of using antiplatelet medication, the resumption rate was 0.5% at discharge, 5% after a month, 12.7% after 3 months, and 29.1% after a year. …”

DataSheet1_Movement and diving behavior of satellite-tagged male sperm whales in the Gulf of Alaska.pdf by Lauren A. Wild (8529753)

“…Whales exhibited slower horizontal movement (1.4 km/hr) within GOA waters compared to south of the GOA (5.5 km/hr), indicating tagged whales sped up when they left the region. …”

Image 4_Behavioral alterations in antibiotic-treated mice associated with gut microbiota dysbiosis: insights from 16S rRNA and metabolomics.tiff by Asma Bibi (12057986)

“…The concentration of serotonin, L-Tyrosine, 5-Hydroxy-L-tryptophan, L-Glutamic acid, L-Glutamate, 5-Hydroxyindole acetic acid, and dopaminergic synapsis was comparatively low, while adenosine was high in antibiotic-treated mice. …”

Image_2_Skeletal Muscle Shape Change in Relation to Varying Force Requirements Across Locomotor Conditions.jpeg by Nicolai Konow (207226)

“…During stance, as the muscle contracts, muscle force increases linearly with respect to gait–slope combinations, and both shortening and lengthening fiber strains increase from approximately 5 to 15% resting length. Contractile change in muscle thickness (thickness strain) decreases (r² = 0.86; p = 0.001); whereas, the change in muscle width (width strain) increases (r² = 0.88; p = 0.001) and tendon strain increases (r² = 0.77; p = 0.015). …”

Cannabinoformins: Designing Biguanide-Embedded, Orally Available, Peripherally Selective Cannabinoid‑1 Receptor Antagonists for Metabolic Syndrome Disorders by Szabolcs Dvorácskó (14767447)

“…We have designed orally bioavailable, non-brain-penetrant antagonists of the cannabinoid-1 receptor (CB₁R) with a built-in biguanide sensor to mimic 5′-adenosine monophosphate kinase (AMPK) activation for treating obesity-associated co-morbidities. …”

DataSheet_1_Body composition and testosterone in men: a Mendelian randomization study.docx by Yoshihiro Ikehata (15993890)

“…Genetically predicted whole body fat mass was negatively associated with TT (β=-0.24, P=5.2×10-³³), BT (β=-0.18, P=5.8×10-²⁰) and SHBG (β=-0.06, P=8.0×10-⁹). …”

Image 3_Behavioral alterations in antibiotic-treated mice associated with gut microbiota dysbiosis: insights from 16S rRNA and metabolomics.tif by Asma Bibi (12057986)

“…The concentration of serotonin, L-Tyrosine, 5-Hydroxy-L-tryptophan, L-Glutamic acid, L-Glutamate, 5-Hydroxyindole acetic acid, and dopaminergic synapsis was comparatively low, while adenosine was high in antibiotic-treated mice. …”

3-Nitropropionic Acid Induces Ovarian Oxidative Stress and Impairs Follicle in Mouse by Jia-Qing Zhang (520605)

“…Female ICR mice were dosed with 3-nitropropionic acid (3-NPA) at three different concentrations (6.25, 12.5 and 25 mg/kg) and saline (control) via continuous intraperitoneal injection for 7 days. …”

DataSheet1_Dissecting the importance and origin of circulating myokines in gastric cancer cachexia.docx by Marek Sierzega (3846406)

“…Cachexia was defined as weight loss >5% or weight loss >2% with either BMI <20 kg/m2 or sarcopenia. …”

Image 1_Behavioral alterations in antibiotic-treated mice associated with gut microbiota dysbiosis: insights from 16S rRNA and metabolomics.tif by Asma Bibi (12057986)

“…The concentration of serotonin, L-Tyrosine, 5-Hydroxy-L-tryptophan, L-Glutamic acid, L-Glutamate, 5-Hydroxyindole acetic acid, and dopaminergic synapsis was comparatively low, while adenosine was high in antibiotic-treated mice. …”

Data_Sheet_1_Experimental warming increases fungal alpha diversity in an oligotrophic maritime Antarctic soil.docx by Kevin K. Newsham (9870623)

“…The substrates reduced alpha and beta diversity metrics by 18–63%, altered community composition and elevated soil fungal DNA concentrations by 1–2 orders of magnitude after 5 years. In glycine-amended soil, OTCs decreased DNA concentrations by 57% and increased the relative abundance of the yeast Vishniacozyma by 45-fold. …”

Image_2_Chicken CH25H inhibits ALV-J replication by promoting cellular autophagy.tif by Tingting Xie (837869)

“…Our results found that overexpression of CH25H and treatment with 25HC promoted the autophagic markers microtubule-associated protein 1 light chain 3 II (LC3II) and autophagy-related gene 5(ATG5), while decreased autophagy substrate p62/SQSTM1 (p62) expression in ALV-J infection DF-1 cells. …”

Table_4_Network pharmacology analysis and experimental verification reveal the mechanism of the traditional Chinese medicine YU-Pingfeng San alleviating allergic rhinitis inflammat... by Zhen Liu (74646)

“…Finally, three hub gene targeting epidermal growth factor receptor (EGFR), mitogen-activated protein kinase 1 (MAPK1), and protein kinase B1 (AKT1) related to YPFS and AR were identified by network pharmacology analysis. YPFS treatment decreased the expression of EGFR, MAPK1, and AKT1 in ovalbumin (OVA)-induced AR mice and impaired the production of inflammatory factors interleukin (IL)-4, IL-5, and IL-13, thus alleviating immunoglobulin E (IgE) production and the symptoms of scratching nose in AR. …”

Data_Sheet_2_CsbZIP2-miR9748-CsNPF4.4 Module Mediates High Temperature Tolerance of Cucumber Through Jasmonic Acid Pathway.PDF by Lan Li (73597)

“…Transcriptome analysis revealed that miR9748 might mediate high temperature tolerance through plant hormone signal pathway. 5′ RNA ligase-mediated rapid amplification of cDNA ends (5′ RLM-RACE) and transient transformation technology demonstrated that CsNPF4.4 was the target gene of miR9748. …”

Supplementary Material for: Comparative efficacy of mesalazine and ozanimod following induction treatment in mesalazine-exposed advanced therapy-naïve in adult ulcerative colitis p... by figshare admin karger (2628495)

“…Results: The two cohorts had similar age (45 ± 14 years vs 44 ± 13.5 years) and baseline disease severity (total Mayo score; 8.5 ± 0.8 vs 8.6 ± 1.1) for mesalazine and ozanimod-treated patients, respectively. …”

Image_1_Is Penicillin Plus Gentamicin Synergistic Against Sessile Group B Streptococcal Isolates? An in Vivo Study With an Experimental Model of Foreign-Body Infection.TIF by Corinne Ruppen (5216951)

“…In a rat tissue cage model, we evaluated the efficacy of adjunctive gentamicin (GEN) administered systemically (5 mg/kg body weight) every 24 h, or locally (12.5 mg/L tissue cage concentration) every 24 or 72 h, in combination with penicillin (PEN) administered systemically (250,000 IU/kg body weight three times per day). …”