zCFTR shows different responses to ATP and phosphate analogues. by Jingyao Zhang (241197)

“…<b>(C)</b> A real time recording of WT-zCFTR shows a slight decrease of the macroscopic current upon switching the ligand from 2 mM ATP to 50 μM P-ATP. …”

Data presented in the paper "Consumer and host body size effects on the removal of trematode cercariae by ambient communities" by J. (Jennifer) Welsh (9158432)

“…One individual was The effect of dilutor size on removal rates of cercariae was investigated in laboratory experiments by determining removal rates of five size categories of each dilutor species (Table 1). In addition, a sixth treatment without dilutors served as a control to account for potential loses of cercariae due other factors (knowing the number of added cercariae was 50) and to test for the presence of a dilution effect (control vs. dilutor size treatments). …”

Expression of Ring1B is influenced by the 5′ UTR. by Erwin Boutsma (377558)

“…All constructs were based on pcDNA3.1 and expression analyses were done with transient transfections in 293 cells, except construct #4, which was based on the retroviral vector MSCV-Puro and was infected in primary MEFs. 50 ng of EGFP-expressing plasmid was cotransfected to be able to judge by fluorescent microscopy whether transfection was comparably efficient. …”

Red Blood Cell Transfusion and Mortality in Trauma Patients: Risk-Stratified Analysis of an Observational Study by Pablo Perel (102217)

“…Transfusion was associated with an increase in all-cause mortality among patients with &lt;6% and 6%–20% predicted risk of death (odds ratio [OR] 5.40, 95% CI 4.08–7.13, <i>p&lt;</i>0.0001, and OR 2.31, 95% CI 1.96–2.73, <i>p&lt;</i>0.0001, respectively), but with a decrease in all-cause mortality in patients with &gt;50% predicted risk of death (OR 0.59, 95% CI 0.47–0.74, <i>p&lt;</i>0.0001). …”

Data_Sheet_1_Molybdenum and Cadmium Co-induce Mitochondrial Quality Control Disorder via FUNDC1-Mediated Mitophagy in Sheep Kidney.doc by Yunhui Wu (2995374)

“…Forty-eight 2-month-old sheep were stochastically divided into four groups, as shown below: control group, Mo [45 mg/kg body weight (BW)] group, Cd (1 mg/kg BW) group and Mo (45 mg/kg BW)+Cd (1 mg/kg BW) group, with 50 days feed technique. The results showed that Mo or/and Cd attract an unbalance of trace minerals and vacuoles and granular degeneration of renal tubular epithelial cells, and increase the number of mitophagosomes and vacuole-mitochondria and LC3 puncta and MDA and H₂O₂ contents, and decrease ATP content in the kidney. …”

Depletion of free PI(3)P, PI(4,5)P₂ and PI(3,4,5)P₃ binding sites in <i>G</i>. <i>lamblia</i> trophozoites elicits uptake and morphological phenotypes. by Lenka Cernikova (2885315)

Equilibrium binding of single strand DNA (P1) from promoter with mNdK by Praveen Kumar (8242)

“…CD spectra of P1 (4 μM) shows decrease in ellipticity at 285 nm with increasing mNdK (0–0.5 μM) in 50 mM Tris-MES-acetate pH 6.5, 1 mM MgCl, 75 mM NaCl within 30 min of incubation, after each addition, at 37°C. () Enzymatic (phosphotransfer) activity of mNdK at pH 6.5. …”

HepR21 cells have increased resilience to nutrient deprivation compared to HepG2 cells. by Paramita Saha (473954)

“…A set of cells were kept as control. The survivability of HepR21 cells was found to remain unaffected while HepG2 cells were highly sensitive upon prolonged starvation with an overall 50% decrease in growth after 36 h of starvation. …”

Gene expression profiles in wildtype, <i>Tnfr1</i>- and <i>Tnfr2-</i>deficient glomeruli after TNF stimulation ex vivo. by Anela Taubitz (433585)

“…<p>Expression profiling by microarrays was performed on isolated glomeruli from wildtype, <i>Tnfr1</i>−/− and <i>Tnfr2</i>−/− mice 12 after stimulation with 50 ng/ml TNF for 12 hours ex vivo. A negativ “fold change” (black to green) indicates decreased expression and a postive “fold change” (black to red) indicates increased expression in a glomerular sample compared with the average of all analyzed samples. …”

Predictive validity. by Roberta Maria Lorenzi (16920886)

“…Simulations last 500 ms with a time resolution of 0.1 ms and <i>υ</i>drive is a step at 50 Hz lasting 250 ms starting at 125 ms. …”

Video_1_Robustness and Scalability of Regional Climate Projections Over Europe.mp4 by Dominic Matte (6270914)

“…<p>Climate change projections for Europe consistently indicate a future decrease in summer precipitation over southern Europe and an increase over northern Europe. …”

Forage yield and structural responses of spineless cactus ‘Orelha de Elefante Mexicana’ at different planting densities by Juliana de Souza Pereira (10442366)

“…The evaluated densities were 20,000; 25,000; 33,333; 50,000; and 100,000 plants ha-1. The increase in planting density caused a linear reduction in plant height, width, and mass, as well as in number of primary, secondary, tertiary, and overall cladodes. …”

Increased proteolysis of YY1 is observed in post-mortem Alzheimer’s disease (AD) brain tissue. by Soline Aubry (507157)

“…Densitometric analysis of immunoblots from BA38 shows (<i>C</i>) a significant decrease (<i>p</i> = 0.02) in the full-length YY1 protein (60 kDa) in AD (<i>n</i> = 15, mAD + sAD) and (<i>D</i>) a significant increase (<i>p</i> = 0.002) in the proportion of proteolytic fragments (35–50 kDa) compared to controls (<i>n</i> = 9). …”

NF-κB activity is required for head formation. by Neil J. Armstrong (323599)

“…(<b>D</b>) Graphical representation of dorsoanterior index (DAI) of control embryos (blue columns) versus embryos injected dorsally with 50 pg of ΔNIκBα (red columns). (<b>E</b>) Time course analysis of embryos injected dorsally with a total of 500 pg ΔNIκBα RNA at the two, four, eight, 16- and 32-cell stage; the accompanying decrease in cell size was compensated by injecting multiple dorsal cells from the 8-cell stage on (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0036136#s4" target="_blank">materials and methods</a>). …”

Accelerated Immunodeficiency by Anti-CCR5 Treatment in HIV Infection by Ariel D. Weinberger (169848)

“…The model shows that the R5-to-X4 switch occurs as CD4⁺ T cell activation levels increase above a threshold and as CD4⁺ T cell counts decrease below a threshold during late-stage HIV infection. …”

Table_2_Small molecules to regulate the GH/IGF1 axis by inhibiting the growth hormone receptor synthesis.xlsx by Lieke M. van der Velden (8841629)

“…In preclinical xenografted experiments, BM001 showed a strong decrease in tumor volume in mice transplanted with MDA‐MB‐231 breast cancer cells. …”

Supplementary Material for: Effect of Dupilumab on Depression in Asthma with Eosinophilic Chronic Rhinosinusitis in the Japanese Population by Koya T. (4155160)

“…In the evaluation 4 months after dupilumab treatment, the PHQ-9 score was significantly reduced, and the decrease was remarkable in patients whose nasal symptom score was reduced by 50% or more. …”

Video_2_Robustness and Scalability of Regional Climate Projections Over Europe.MP4 by Dominic Matte (6270914)

“…<p>Climate change projections for Europe consistently indicate a future decrease in summer precipitation over southern Europe and an increase over northern Europe. …”

Impaired Sprouting and Axonal Atrophy in Cerebellar Climbing Fibres following <em>In Vivo</em> Silencing of the Growth-Associated Protein GAP-43 by Giorgio Grasselli (217929)

“…We show that lack of GAP-43 causes an atrophy of the CF in non-traumatic conditions, consisting in a decrease of its length, branching and number of synaptic boutons. …”

PHOSPHORUS FERTILIZATION AND SOIL TEXTURE AFFECT POTATO YIELD by JÉSSYCA DELLINHARES LOPES MARTINS (6117419)

“…<div><p>ABSTRACT Potato (Solanum tuberosum L.) is a nutritionally demanding crop, and phosphorus (P) is a nutrient that exerts a large effect on tuber yield. …”